quinisocaine-4791 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the quinisocaine-4791 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR2 angiotensin II receptor, type 2
APC adenomatous polyposis coli
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARMC4 armadillo repeat containing 4
ASIC4 acid sensing (proton gated) ion channel family member 4
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C8ORF60 chromosome 8 open reading frame 60
CALCR calcitonin receptor
CCNG2 cyclin G2
CD300C CD300c molecule
CD46 CD46 molecule, complement regulatory protein
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHD1L chromodomain helicase DNA binding protein 1-like
CLUAP1 clusterin associated protein 1
DDIT3 DNA-damage-inducible transcript 3
DPY19L1P1 DPY19L1 pseudogene 1
DSCAM Down syndrome cell adhesion molecule
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EGR1 early growth response 1
EGR4 early growth response 4
EIF3F eukaryotic translation initiation factor 3, subunit F
EPOR erythropoietin receptor
FGF18 fibroblast growth factor 18
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRMD4B FERM domain containing 4B
FRMPD4 FERM and PDZ domain containing 4
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GPR1 G protein-coupled receptor 1
GPR68 G protein-coupled receptor 68
GSK3A glycogen synthase kinase 3 alpha
GULP1 GULP, engulfment adaptor PTB domain containing 1
GYPB glycophorin B (MNS blood group)
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H3B histone cluster 1, H3b
HOXC5 homeobox C5
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLK13 kallikrein-related peptidase 13
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MBD1 methyl-CpG binding domain protein 1
MCL1 myeloid cell leukemia 1
MYL10 myosin, light chain 10, regulatory
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRL neural retina leucine zipper
NTF3 neurotrophin 3
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2A olfactomedin-like 2A
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH11Y protocadherin 11 Y-linked
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER1 period circadian clock 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PICALM phosphatidylinositol binding clathrin assembly protein
PICK1 protein interacting with PRKCA 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
RAB11B RAB11B, member RAS oncogene family
RAD51 RAD51 recombinase
RPGR retinitis pigmentosa GTPase regulator
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA4 serum amyloid A4, constitutive
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMAD5 SMAD family member 5
SOS1 son of sevenless homolog 1 (Drosophila)
SPTB spectrin, beta, erythrocytic
SQLE squalene epoxidase
TBKBP1 TBK1 binding protein 1
TGFB2 transforming growth factor, beta 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM15 tripartite motif containing 15
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TUBA3C tubulin, alpha 3c
VARS valyl-tRNA synthetase
WDTC1 WD and tetratricopeptide repeats 1
WNT16 wingless-type MMTV integration site family, member 16
ZBTB17 zinc finger and BTB domain containing 17
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF280A zinc finger protein 280A
ZNF442 zinc finger protein 442
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
APOLD1 apolipoprotein L domain containing 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASB9 ankyrin repeat and SOCS box containing 9
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBS10 Bardet-Biedl syndrome 10
BCAS1 breast carcinoma amplified sequence 1
C2ORF44 chromosome 2 open reading frame 44
CD79B CD79b molecule, immunoglobulin-associated beta
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRABP1 cellular retinoic acid binding protein 1
CRYBG3 beta-gamma crystallin domain containing 3
DEAF1 DEAF1 transcription factor
DTX4 deltex 4, E3 ubiquitin ligase
E4F1 E4F transcription factor 1
ENO2 enolase 2 (gamma, neuronal)
EXD3 exonuclease 3'-5' domain containing 3
FAM222B family with sequence similarity 222, member B
FBXO22 F-box protein 22
FBXO46 F-box protein 46
FOCAD focadhesin
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GOLGA8B golgin A8 family, member B
GPATCH1 G patch domain containing 1
GTPBP2 GTP binding protein 2
HPN hepsin
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IQSEC2 IQ motif and Sec7 domain 2
KAT2A K(lysine) acetyltransferase 2A
KATNBL1 katanin p80 subunit B-like 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
LINS lines homolog (Drosophila)
LRRC8E leucine rich repeat containing 8 family, member E
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
MAGEF1 melanoma antigen family F1
MAMLD1 mastermind-like domain containing 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MRPS18C mitochondrial ribosomal protein S18C
MUC3B mucin 3B, cell surface associated
MXD3 MAX dimerization protein 3
NCAM2 neural cell adhesion molecule 2
NHEJ1 nonhomologous end-joining factor 1
NRTN neurturin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARD6A par-6 family cell polarity regulator alpha
PARP16 poly (ADP-ribose) polymerase family, member 16
PCNXL4 pecanex-like 4 (Drosophila)
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRICKLE3 prickle homolog 3 (Drosophila)
PRKX protein kinase, X-linked
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAI14 retinoic acid induced 14
RNF220 ring finger protein 220
RNF31 ring finger protein 31
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCAMP4 secretory carrier membrane protein 4
SDC3 syndecan 3
SKI SKI proto-oncogene
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPINK5 serine peptidase inhibitor, Kazal type 5
STEAP4 STEAP family member 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBL3 transducin (beta)-like 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGS1 trimethylguanosine synthase 1
TLR5 toll-like receptor 5
TMEM110 transmembrane protein 110
TMEM121 transmembrane protein 121
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
VAV1 vav 1 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
ZBTB25 zinc finger and BTB domain containing 25
ZNF324 zinc finger protein 324
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747