quercetin-917 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the quercetin-917 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ADAM2 ADAM metallopeptidase domain 2
APOE apolipoprotein E
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATRX alpha thalassemia/mental retardation syndrome X-linked
C18ORF25 chromosome 18 open reading frame 25
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLCF1 cardiotrophin-like cytokine factor 1
CRYGC crystallin, gamma C
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DACH1 dachshund family transcription factor 1
DCAKD dephospho-CoA kinase domain containing
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK3 dedicator of cytokinesis 3
DSC3 desmocollin 3
EHD2 EH-domain containing 2
EPHB2 EPH receptor B2
FAM212B family with sequence similarity 212, member B
FBXO2 F-box protein 2
FBXO38 F-box protein 38
FGFR3 fibroblast growth factor receptor 3
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXL1 forkhead box L1
GIF gastric intrinsic factor (vitamin B synthesis)
GM2A GM2 ganglioside activator
GPATCH2L G patch domain containing 2-like
GSPT1 G1 to S phase transition 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXD13 homeobox D13
HSPB11 heat shock protein family B (small), member 11
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL23A interleukin 23, alpha subunit p19
KCTD12 potassium channel tetramerization domain containing 12
KIAA1109 KIAA1109
LHX6 LIM homeobox 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP1A microtubule-associated protein 1A
MAPK14 mitogen-activated protein kinase 14
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED25 mediator complex subunit 25
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR3 myotubularin related protein 3
NEBL nebulette
NF2 neurofibromin 2 (merlin)
OASL 2'-5'-oligoadenylate synthetase-like
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLTP phospholipid transfer protein
PRKCI protein kinase C, iota
PRLR prolactin receptor
PYY2 peptide YY, 2 (pseudogene)
RAB6A RAB6A, member RAS oncogene family
RCOR3 REST corepressor 3
RNF122 ring finger protein 122
RNF6 ring finger protein (C3H2C3 type) 6
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1 runt-related transcription factor 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3BP2 SH3-domain binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX4 SRY (sex determining region Y)-box 4
SPATA1 spermatogenesis associated 1
SPATS2L spermatogenesis associated, serine-rich 2-like
SPTBN1 spectrin, beta, non-erythrocytic 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STS steroid sulfatase (microsomal), isozyme S
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBX3 T-box 3
TENM4 teneurin transmembrane protein 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS4 transmembrane protease, serine 4
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPM2 tropomyosin 2 (beta)
TRAPPC9 trafficking protein particle complex 9
UBXN1 UBX domain protein 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VARS valyl-tRNA synthetase
VAV2 vav 2 guanine nucleotide exchange factor
ZNF211 zinc finger protein 211
ZNF682 zinc finger protein 682
ZNF816 zinc finger protein 816
ZNF821 zinc finger protein 821
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD36B ankyrin repeat domain 36B
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP13A2 ATPase type 13A2
AUNIP aurora kinase A and ninein interacting protein
BBC3 BCL2 binding component 3
CARD8 caspase recruitment domain family, member 8
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPO centromere protein O
CFD complement factor D (adipsin)
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CLDN9 claudin 9
CORT cortistatin
DMTN dematin actin binding protein
DTX4 deltex 4, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
F8 coagulation factor VIII, procoagulant component
FBXO22 F-box protein 22
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FLJ22184
GFOD1 glucose-fructose oxidoreductase domain containing 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
IPP intracisternal A particle-promoted polypeptide
JADE1 jade family PHD finger 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC100272216 uncharacterized LOC100272216
LYPD1 LY6/PLAUR domain containing 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MATK megakaryocyte-associated tyrosine kinase
MCOLN1 mucolipin 1
MNS1 meiosis-specific nuclear structural 1
MPI mannose phosphate isomerase
MRPS18C mitochondrial ribosomal protein S18C
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR6 progestin and adipoQ receptor family member VI
PHACTR4 phosphatase and actin regulator 4
PLA2G15 phospholipase A2, group XV
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRPH peripherin
PTK6 protein tyrosine kinase 6
RBM42 RNA binding motif protein 42
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
SART1 squamous cell carcinoma antigen recognized by T cells
SCAI suppressor of cancer cell invasion
SETD6 SET domain containing 6
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNIP1 Smad nuclear interacting protein 1
SPATA7 spermatogenesis associated 7
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
THAP7 THAP domain containing 7
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMEM183A transmembrane protein 183A
TRABD TraB domain containing
TRAPPC13 trafficking protein particle complex 13
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF160 zinc finger protein 160
ZNF189 zinc finger protein 189
ZNF268 zinc finger protein 268
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF430 zinc finger protein 430
ZNF510 zinc finger protein 510
ZNF7 zinc finger protein 7
ZNF721 zinc finger protein 721
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778
ZNF85 zinc finger protein 85
ZNF91 zinc finger protein 91