pyrvinium-2957 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the pyrvinium-2957 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACOT11 acyl-CoA thioesterase 11
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
AURKA aurora kinase A
AVPI1 arginine vasopressin-induced 1
BCL3 B-cell CLL/lymphoma 3
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BTG2 BTG family, member 2
C5AR1 complement component 5a receptor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CD70 CD70 molecule
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP72 centrosomal protein 72kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCF1 cardiotrophin-like cytokine factor 1
CNTN1 contactin 1
COL4A2 collagen, type IV, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EPHB6 EPH receptor B6
EXD3 exonuclease 3'-5' domain containing 3
FCMR Fc fragment of IgM receptor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FRY furry homolog (Drosophila)
FTH1 ferritin, heavy polypeptide 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPR183 G protein-coupled receptor 183
GRAMD3 GRAM domain containing 3
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA5 homeobox A5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IL23A interleukin 23, alpha subunit p19
IL24 interleukin 24
INHBA inhibin, beta A
JAG1 jagged 1
JUNB jun B proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MCF2L MCF.2 cell line derived transforming sequence-like
MT2A metallothionein 2A
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OSM oncostatin M
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PLAUR plasminogen activator, urokinase receptor
PRDM1 PR domain containing 1, with ZNF domain
QPRT quinolinate phosphoribosyltransferase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RHOB ras homolog family member B
RHOD ras homolog family member D
RND1 Rho family GTPase 1
RTCA RNA 3'-terminal phosphate cyclase
RUFY3 RUN and FYVE domain containing 3
RXRA retinoid X receptor, alpha
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SH2D2A SH2 domain containing 2A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIK1 salt-inducible kinase 1
SKIL SKI-like proto-oncogene
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SOCS3 suppressor of cytokine signaling 3
STON1 stonin 1
STX11 syntaxin 11
TAPT1 transmembrane anterior posterior transformation 1
TARP TCR gamma alternate reading frame protein
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TYMP thymidine phosphorylase

decreased expression

Symbol Name
ADM adrenomedullin
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C21ORF59 chromosome 21 open reading frame 59
C2CD2 C2 calcium-dependent domain containing 2
CCDC51 coiled-coil domain containing 51
CCNE1 cyclin E1
CCNE2 cyclin E2
CCR2 chemokine (C-C motif) receptor 2
CHMP7 charged multivesicular body protein 7
COA7 cytochrome c oxidase assembly factor 7 (putative)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBRD1 cytochrome b reductase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHRS9 dehydrogenase/reductase (SDR family) member 9
EGLN1 egl-9 family hypoxia-inducible factor 1
ENO2 enolase 2 (gamma, neuronal)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM57A family with sequence similarity 57, member A
FASTKD5 FAST kinase domains 5
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GCHFR GTP cyclohydrolase I feedback regulator
GCLM glutamate-cysteine ligase, modifier subunit
GIMAP6 GTPase, IMAP family member 6
GJA1 gap junction protein, alpha 1, 43kDa
HCAR3 hydroxycarboxylic acid receptor 3
HELLS helicase, lymphoid-specific
HILPDA hypoxia inducible lipid droplet-associated
HSPA4L heat shock 70kDa protein 4-like
INSIG2 insulin induced gene 2
KDM3A lysine (K)-specific demethylase 3A
KLHL26 kelch-like family member 26
LINS lines homolog (Drosophila)
LRRC42 leucine rich repeat containing 42
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM3AP-AS1 MCM3AP antisense RNA 1
MCMBP minichromosome maintenance complex binding protein
METTL8 methyltransferase like 8
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MOSPD3 motile sperm domain containing 3
MSRB1 methionine sulfoxide reductase B1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFE2 nuclear factor, erythroid 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OXSM 3-oxoacyl-ACP synthase, mitochondrial
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PBX3 pre-B-cell leukemia homeobox 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PHACTR1 phosphatase and actin regulator 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAG1 pleiomorphic adenoma gene 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNOC prepronociceptin
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRDM13 PR domain containing 13
PTGES2 prostaglandin E synthase 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RFXAP regulatory factor X-associated protein
RGS13 regulator of G-protein signaling 13
RLF rearranged L-myc fusion
RRAGA Ras-related GTP binding A
SALL2 spalt-like transcription factor 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPP1 secreted phosphoprotein 1
STBD1 starch binding domain 1
TCTN1 tectonic family member 1
TMEM45A transmembrane protein 45A
TSFM Ts translation elongation factor, mitochondrial
TUBB6 tubulin, beta 6 class V
UBE2O ubiquitin-conjugating enzyme E2O
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VGLL4 vestigial-like family member 4
WDR3 WD repeat domain 3
WT1-AS WT1 antisense RNA
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZNF395 zinc finger protein 395
ZNF574 zinc finger protein 574
ZNF654 zinc finger protein 654