purkinje layer Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The cerebellar cortex is divided into three layers. At the bottom lies the thick granular layer. In the middle lies the Purkinje layer, a narrow zone that contains only the cell bodies of Purkinje cells. At the top lies the molecular layer. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004909)
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Genes

187 proteins co-occuring with the tissue purkinje layer in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CALB1 calbindin 1, 28kDa 1.29399
RLIM ring finger protein, LIM domain interacting 1.194
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 1.1869
WDR81 WD repeat domain 81 1.11376
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.99586
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.981084
MPRIP myosin phosphatase Rho interacting protein 0.97285
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.968955
FBXO25 F-box protein 25 0.96636
CSAD cysteine sulfinic acid decarboxylase 0.964199
PLXDC2 plexin domain containing 2 0.963767
FJX1 four jointed box 1 (Drosophila) 0.954703
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.947809
SOX1 SRY (sex determining region Y)-box 1 0.939206
SSTR3 somatostatin receptor 3 0.915642
PEX13 peroxisomal biogenesis factor 13 0.908814
TTBK2 tau tubulin kinase 2 0.908387
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.887981
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.887133
NCDN neurochondrin 0.882051
GFAP glial fibrillary acidic protein 0.869373
ATCAY ataxia, cerebellar, Cayman type 0.860521
SYBU syntabulin (syntaxin-interacting) 0.858837
SYP synaptophysin 0.837414
LRRC4 leucine rich repeat containing 4 0.822339
NCS1 neuronal calcium sensor 1 0.817322
CRH corticotropin releasing hormone 0.803544
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 0.803544
TECTA tectorin alpha 0.79146
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.780648
CERS6 ceramide synthase 6 0.774834
FGF9 fibroblast growth factor 9 0.765296
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.764882
PLXDC1 plexin domain containing 1 0.736382
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.703127
PITPNB phosphatidylinositol transfer protein, beta 0.70108
PURA purine-rich element binding protein A 0.692493
PITPNA phosphatidylinositol transfer protein, alpha 0.688
FGF14 fibroblast growth factor 14 0.660304
NEU1 sialidase 1 (lysosomal sialidase) 0.654618
PLXNB2 plexin B2 0.652589
GDF10 growth differentiation factor 10 0.651777
KIRREL3 kin of IRRE like 3 (Drosophila) 0.639619
PRNP prion protein 0.63719
EDN2 endothelin 2 0.632335
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.631527
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.62991
DLAT dihydrolipoamide S-acetyltransferase 0.624254
EN2 engrailed homeobox 2 0.621831
UGT8 UDP glycosyltransferase 8 0.619007
FIG4 FIG4 phosphoinositide 5-phosphatase 0.6182
TNK2 tyrosine kinase, non-receptor, 2 0.61578
CDH8 cadherin 8, type 2 0.611346
ZNF423 zinc finger protein 423 0.598067
KIRREL2 kin of IRRE like 2 (Drosophila) 0.593649
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.591641
CLIC4 chloride intracellular channel 4 0.590839
RERE arginine-glutamic acid dipeptide (RE) repeats 0.588832
MAP1A microtubule-associated protein 1A 0.584422
KCNIP4 Kv channel interacting protein 4 0.578016
BEAN1 brain expressed, associated with NEDD4, 1 0.559254
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.558856
GRID2 glutamate receptor, ionotropic, delta 2 0.55607
PLCB4 phospholipase C, beta 4 0.553683
EN1 engrailed homeobox 1 0.552093
CLN5 ceroid-lipofuscinosis, neuronal 5 0.545739
SOX9 SRY (sex determining region Y)-box 9 0.529113
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.52556
CALCA calcitonin-related polypeptide alpha 0.522405
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.518072
SGCE sarcoglycan, epsilon 0.514924
WNT8B wingless-type MMTV integration site family, member 8B 0.513743
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.51335
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.502357
PLCD1 phospholipase C, delta 1 0.500398
NGFR nerve growth factor receptor 0.499615
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.496483
ATXN2 ataxin 2 0.494136
STK26 serine/threonine protein kinase 26 0.492963
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.479312
NES nestin 0.473869
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.471539
SPTBN1 spectrin, beta, non-erythrocytic 1 0.466111
BLVRA biliverdin reductase A 0.462626
GAL3ST1 galactose-3-O-sulfotransferase 1 0.460692
SIM2 single-minded family bHLH transcription factor 2 0.459532
MANF mesencephalic astrocyte-derived neurotrophic factor 0.458759
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.457987
RYR1 ryanodine receptor 1 (skeletal) 0.4576
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.456055
FNDC3A fibronectin type III domain containing 3A 0.45567
CXCR5 chemokine (C-X-C motif) receptor 5 0.454898
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.451042
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.448731
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.445653
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.443347
SDC3 syndecan 3 0.437972
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.437205
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.432991
NOTCH2NL notch 2 N-terminal like 0.42993
PTPRB protein tyrosine phosphatase, receptor type, B 0.429547
NOTCH2 notch 2 0.426872
GPR17 G protein-coupled receptor 17 0.416957
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.412391
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.405935
TH tyrosine hydroxylase 0.405555
HYOU1 hypoxia up-regulated 1 0.40328
SNAP25 synaptosomal-associated protein, 25kDa 0.402901
GAS1 growth arrest-specific 1 0.401007
PDYN prodynorphin 0.397222
PENK proenkephalin 0.394197
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.394197
SNRPN small nuclear ribonucleoprotein polypeptide N 0.391176
ADRA2C adrenoceptor alpha 2C 0.388158
CHAT choline O-acetyltransferase 0.387404
SNED1 sushi, nidogen and EGF-like domains 1 0.38552
SST somatostatin 0.382131
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.372743
DHH desert hedgehog 0.36825
MT3 metallothionein 3 0.366381
TTPA tocopherol (alpha) transfer protein 0.357802
ERCC5 excision repair cross-complementation group 5 0.357058
NOTCH1 notch 1 0.352227
VIM vimentin 0.351856
STK4 serine/threonine kinase 4 0.350743
GFRA1 GDNF family receptor alpha 1 0.342602
RICTOR RPTOR independent companion of MTOR, complex 2 0.341495
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.337808
PTN pleiotrophin 0.336214
DPYSL2 dihydropyrimidinase-like 2 0.328262
ANXA6 annexin A6 0.326432
RELN reelin 0.326432
TNC tenascin C 0.326067
SSTR4 somatostatin receptor 4 0.320591
ACP2 acid phosphatase 2, lysosomal 0.319863
PDE5A phosphodiesterase 5A, cGMP-specific 0.315861
GALR1 galanin receptor 1 0.313683
HSPE1 heat shock 10kDa protein 1 0.312957
GABARAP GABA(A) receptor-associated protein 0.311507
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.311507
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.310783
RYR3 ryanodine receptor 3 0.307889
GRM7 glutamate receptor, metabotropic 7 0.30464
CXCL14 chemokine (C-X-C motif) ligand 14 0.303919
EFNA1 ephrin-A1 0.303919
BTNL2 butyrophilin-like 2 0.302118
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.29996
CRY2 cryptochrome circadian clock 2 0.294223
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.293508
OPA1 optic atrophy 1 (autosomal dominant) 0.293151
CA8 carbonic anhydrase VIII 0.291722
NPS neuropeptide S 0.290652
LYN LYN proto-oncogene, Src family tyrosine kinase 0.288158
BMP3 bone morphogenetic protein 3 0.287803
JAG1 jagged 1 0.286499
CALB2 calbindin 2 0.285316
PRIMA1 proline rich membrane anchor 1 0.283545
CUL1 cullin 1 0.275794
GDNF glial cell derived neurotrophic factor 0.2723
GRM1 glutamate receptor, metabotropic 1 0.270909
GAL galanin/GMAP prepropeptide 0.269867
FOS FBJ murine osteosarcoma viral oncogene homolog 0.269174
CRHR1 corticotropin releasing hormone receptor 1 0.267791
SHH sonic hedgehog 0.264696
PLAT plasminogen activator, tissue 0.263327
NGF nerve growth factor (beta polypeptide) 0.262645
HGFAC HGF activator 0.259591
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.242363
ATOH1 atonal homolog 1 (Drosophila) 0.236921
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.23604
PHYH phytanoyl-CoA 2-hydroxylase 0.23459
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.233162
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.23011
DLL1 delta-like 1 (Drosophila) 0.229121
PVALB parvalbumin 0.226411
EFNA5 ephrin-A5 0.222699
FYN FYN proto-oncogene, Src family tyrosine kinase 0.22246
PCNA proliferating cell nuclear antigen 0.220152
CA4 carbonic anhydrase IV 0.219485
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.217762
SKP1 S-phase kinase-associated protein 1 0.216528
APOD apolipoprotein D 0.21573
CHGB chromogranin B 0.215147
GPHN gephyrin 0.214765
DCX doublecortin 0.212528
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.198487
PGF placental growth factor 0.196232