purine metabolism Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). (Gene Ontology, GO_0042278)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa00230.html
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Genes

139 proteins participating in the purine metabolism pathway from the KEGG Pathways dataset.

Symbol Name
ADA adenosine deaminase
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADK adenosine kinase
ADSL adenylosuccinate lyase
ADSS adenylosuccinate synthase
ADSSL1 adenylosuccinate synthase like 1
AK1 adenylate kinase 1
AK2 adenylate kinase 2
AK5 adenylate kinase 5
AK7 adenylate kinase 7
ALLC allantoicase
AMPD1 adenosine monophosphate deaminase 1
AMPD2 adenosine monophosphate deaminase 2
AMPD3 adenosine monophosphate deaminase 3
APRT adenine phosphoribosyltransferase
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
CANT1 calcium activated nucleotidase 1
DCK deoxycytidine kinase
DGUOK deoxyguanosine kinase
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
FHIT fragile histidine triad
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GDA guanine deaminase
GMPR guanosine monophosphate reductase
GMPR2 guanosine monophosphate reductase 2
GMPS guanine monphosphate synthase
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUCY2C guanylate cyclase 2C
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GUCY2F guanylate cyclase 2F, retinal
GUK1 guanylate kinase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
NME6 NME/NM23 nucleoside diphosphate kinase 6
NME7 NME/NM23 family member 7
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NT5C 5', 3'-nucleotidase, cytosolic
NT5C1A 5'-nucleotidase, cytosolic IA
NT5C1B 5'-nucleotidase, cytosolic IB
NT5C2 5'-nucleotidase, cytosolic II
NT5E 5'-nucleotidase, ecto (CD73)
NT5M 5',3'-nucleotidase, mitochondrial
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE10A phosphodiesterase 10A
PDE11A phosphodiesterase 11A
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDE7A phosphodiesterase 7A
PDE7B phosphodiesterase 7B
PDE8A phosphodiesterase 8A
PDE8B phosphodiesterase 8B
PDE9A phosphodiesterase 9A
PFAS phosphoribosylformylglycinamidine synthase
PKLR pyruvate kinase, liver and RBC
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPAT phosphoribosyl pyrophosphate amidotransferase
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRUNE prune exopolyphosphatase
RFC5 replication factor C (activator 1) 5, 36.5kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
XDH xanthine dehydrogenase
ZNRD1 zinc ribbon domain containing 1