pterygium Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A fleshy mass of thickened conjunctiva that grows over part of the cornea usually from the inner side of the eyeball and causes a disturbance of vision. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005180)
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Genes

119 proteins co-occuring with the tissue pterygium in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.49819
CHRND cholinergic receptor, nicotinic, delta (muscle) 1.62008
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.34134
PSPHP1 phosphoserine phosphatase pseudogene 1 1.33048
DOK7 docking protein 7 1.25816
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.21757
TP53 tumor protein p53 1.18334
RAPSN receptor-associated protein of the synapse 1.16072
CCIN calicin 1.0828
CIB2 calcium and integrin binding family member 2 1.06912
TCTEX1D4 Tctex1 domain containing 4 1.03214
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.975015
IPO13 importin 13 0.972417
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.95729
KRT12 keratin 12, type I 0.924194
FLAD1 flavin adenine dinucleotide synthetase 1 0.905831
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.852948
TFF1 trefoil factor 1 0.845385
TFF3 trefoil factor 3 (intestinal) 0.778986
TNNI2 troponin I type 2 (skeletal, fast) 0.762397
PRDX2 peroxiredoxin 2 0.752884
TNNT3 troponin T type 3 (skeletal, fast) 0.731031
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.722398
MMP1 matrix metallopeptidase 1 0.703945
DEFA3 defensin, alpha 3, neutrophil-specific 0.70108
KRT15 keratin 15, type I 0.699035
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.693311
KRT6A keratin 6A, type II 0.671285
CDKN2A cyclin-dependent kinase inhibitor 2A 0.661929
HBA1 hemoglobin, alpha 1 0.654618
MMP2 matrix metallopeptidase 2 0.650966
HBA2 hemoglobin, alpha 2 0.641238
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.63719
TFF2 trefoil factor 2 0.626677
MMP9 matrix metallopeptidase 9 0.614974
S100A9 S100 calcium binding protein A9 0.607319
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.596058
CNTN1 contactin 1 0.596058
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.578016
NCF4 neutrophil cytosolic factor 4, 40kDa 0.568025
FOXE1 forkhead box E1 0.566828
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.564035
MMP3 matrix metallopeptidase 3 0.56005
VEGFC vascular endothelial growth factor C 0.544946
AK2 adenylate kinase 2 0.544152
KRT83 keratin 83, type II 0.538604
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.535042
S100A11 S100 calcium binding protein A11 0.52635
FBLN5 fibulin 5 0.523982
S100A8 S100 calcium binding protein A8 0.512171
REEP5 receptor accessory protein 5 0.492963
SYNE1 spectrin repeat containing, nuclear envelope 1 0.491009
VEGFA vascular endothelial growth factor A 0.489057
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.483206
LOXL1 lysyl oxidase-like 1 0.472704
CD68 CD68 molecule 0.460305
IRF6 interferon regulatory factor 6 0.452198
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.449886
PLD1 phospholipase D1, phosphatidylcholine-specific 0.447192
PDIA3 protein disulfide isomerase family A, member 3 0.446422
KRT17 keratin 17, type I 0.426872
KRT13 keratin 13, type I 0.421529
MKI67 marker of proliferation Ki-67 0.420004
SAT1 spermidine/spermine N1-acetyltransferase 1 0.416195
GSTM1 glutathione S-transferase mu 1 0.409351
ZMPSTE24 zinc metallopeptidase STE24 0.409351
KLK8 kallikrein-related peptidase 8 0.407453
KRT4 keratin 4, type II 0.404418
MLANA melan-A 0.397979
TCF12 transcription factor 12 0.395331
GP5 glycoprotein V (platelet) 0.391553
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.390799
FGF2 fibroblast growth factor 2 (basic) 0.388158
MIR221 microRNA 221 0.37687
SPN sialophorin 0.371994
TPM2 tropomyosin 2 (beta) 0.367502
H2AFY H2A histone family, member Y 0.364139
FLT1 fms-related tyrosine kinase 1 0.354455
HBEGF heparin-binding EGF-like growth factor 0.351114
RIPK4 receptor-interacting serine-threonine kinase 4 0.34963
MIR145 microRNA 145 0.34963
FGF3 fibroblast growth factor 3 0.348889
FBN2 fibrillin 2 0.345928
KRT3 keratin 3, type II 0.341126
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.337072
DCN decorin 0.334865
EFNB1 ephrin-B1 0.33413
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.333396
MMP7 matrix metallopeptidase 7 0.325335
MSMB microseminoprotein, beta- 0.322779
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.319134
SCG5 secretogranin V 0.319134
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.318407
LRP6 low density lipoprotein receptor-related protein 6 0.312957
PCNA proliferating cell nuclear antigen 0.312595
EPHB4 EPH receptor B4 0.307889
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.306444
LOX lysyl oxidase 0.304279
S100A6 S100 calcium binding protein A6 0.302118
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.28213
TIMP1 TIMP metallopeptidase inhibitor 1 0.278603
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.264353
EGFR epidermal growth factor receptor 0.264353
DPT dermatopontin 0.258917
OGG1 8-oxoguanine DNA glycosylase 0.253248
TP63 tumor protein p63 0.248683
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.246442
USF1 upstream transcription factor 1 0.240216
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.239913
ITGB4 integrin, beta 4 0.236627
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.236332
TIMP2 TIMP metallopeptidase inhibitor 2 0.235167
JUN jun proto-oncogene 0.232317
TGFB1 transforming growth factor, beta 1 0.230931
MUC6 mucin 6, oligomeric mucus/gel-forming 0.227186
EFNB2 ephrin-B2 0.22415
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.223906
PLK1 polo-like kinase 1 0.217139
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.213291