pterygium Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed) (Experimental Factor Ontology, EFO_0000678)
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Genes

61 genes co-occuring with the biological term pterygium in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ANG angiogenin, ribonuclease, RNase A family, 5
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CREB1 cAMP responsive element binding protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
ELN elastin
ENG endoglin
EPOR erythropoietin receptor
ERCC2 excision repair cross-complementation group 2
F3 coagulation factor III (thromboplastin, tissue factor)
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
GBE1 glucan (1,4-alpha-), branching enzyme 1
GSTM1 glutathione S-transferase mu 1
HES3 hes family bHLH transcription factor 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
IPO13 importin 13
IRF6 interferon regulatory factor 6
KDR kinase insert domain receptor
LACRT lacritin
MIR145 microRNA 145
MIR200A microRNA 200a
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR221 microRNA 221
MKI67 marker of proliferation Ki-67
MMP3 matrix metallopeptidase 3
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYCBP MYC binding protein
NES nestin
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
PCNA proliferating cell nuclear antigen
PLAUR plasminogen activator, urokinase receptor
PRDX2 peroxiredoxin 2
PROX1 prospero homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RIPK4 receptor-interacting serine-threonine kinase 4
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XPA xeroderma pigmentosum, complementation group A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6