psoriatic arthritis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A syndrome that occurs in humans with psoriasis who also experience symptoms similar to arthritis. (Human Disease Ontology, DOID_9008)
Similar Terms
Downloads & Tools

Genes

166 genes co-occuring with the disease psoriatic arthritis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.71702
TNF tumor necrosis factor 1.81465
MRAP melanocortin 2 receptor accessory protein 1.70497
PHB2 prohibitin 2 1.56844
TRAF3IP2 TRAF3 interacting protein 2 1.48867
CRP C-reactive protein, pentraxin-related 1.4834
FBXL19 F-box and leucine-rich repeat protein 19 1.38909
HLA-C major histocompatibility complex, class I, C 1.35986
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.18324
HLA-A major histocompatibility complex, class I, A 1.14857
ERAP1 endoplasmic reticulum aminopeptidase 1 1.1367
TNIP1 TNFAIP3 interacting protein 1 1.1367
LCE3C late cornified envelope 3C 1.12867
LCE3B late cornified envelope 3B 1.12277
MICA MHC class I polypeptide-related sequence A 1.08412
RNF114 ring finger protein 114 1.02524
ZNF816 zinc finger protein 816 1.01976
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.987271
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 0.9717
IL17A interleukin 17A 0.963309
LCE3D late cornified envelope 3D 0.948269
MMP3 matrix metallopeptidase 3 0.934141
HLA-E major histocompatibility complex, class I, E 0.922561
COG6 component of oligomeric golgi complex 6 0.891308
CD4 CD4 molecule 0.887208
COMP cartilage oligomeric matrix protein 0.8741
IL1RN interleukin 1 receptor antagonist 0.8741
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3 0.862228
HLA-B major histocompatibility complex, class I, B 0.824948
CD79A CD79a molecule, immunoglobulin-associated alpha 0.800333
IL1B interleukin 1, beta 0.795002
S100A12 S100 calcium binding protein A12 0.794181
IL23R interleukin 23 receptor 0.756971
USP8 ubiquitin specific peptidase 8 0.720865
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.715215
PDE4A phosphodiesterase 4A, cAMP-specific 0.707961
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.691495
PLCL2 phospholipase C-like 2 0.678701
CCHCR1 coiled-coil alpha-helical rod protein 1 0.635528
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.631598
LTA lymphotoxin alpha 0.625319
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 0.623359
CD58 CD58 molecule 0.614356
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.609666
CDSN corneodesmosin 0.606543
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.6003
SLC12A8 solute carrier family 12, member 8 0.597181
IL22 interleukin 22 0.591727
CARD14 caspase recruitment domain family, member 14 0.589779
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.587054
IFNLR1 interferon, lambda receptor 1 0.575383
S100A9 S100 calcium binding protein A9 0.562169
DHODH dihydroorotate dehydrogenase (quinone) 0.562169
CD68 CD68 molecule 0.554791
AFF3 AF4/FMR2 family, member 3 0.552463
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.541217
SELE selectin E 0.540055
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.528449
KIAA1109 KIAA1109 0.523816
IL6 interleukin 6 0.523816
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.522273
S100A8 S100 calcium binding protein A8 0.518805
MIA melanoma inhibitory activity 0.510344
CRTAC1 cartilage acidic protein 1 0.509192
IL17RA interleukin 17 receptor A 0.507273
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 0.504207
RNF39 ring finger protein 39 0.504207
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.493885
C3 complement component 3 0.469197
PSME4 proteasome (prosome, macropain) activator subunit 4 0.456355
SPPL2A signal peptide peptidase like 2A 0.455978
RBM38 RNA binding motif protein 38 0.448817
IL2 interleukin 2 0.44129
DYNLT1 dynein, light chain, Tctex-type 1 0.428891
NOD2 nucleotide-binding oligomerization domain containing 2 0.42814
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.42289
RAN RAN, member RAS oncogene family 0.416147
IL1A interleukin 1, alpha 0.413153
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.397471
LHFP lipoma HMGIC fusion partner 0.396725
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.392629
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.392629
ZNF395 zinc finger protein 395 0.388538
RPTOR regulatory associated protein of MTOR, complex 1 0.387051
IL2RA interleukin 2 receptor, alpha 0.386308
SAA1 serum amyloid A1 0.385565
UST uronyl-2-sulfotransferase 0.363347
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.357814
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.353395
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.353395
HBA2 hemoglobin, alpha 2 0.346409
CXCL10 chemokine (C-X-C motif) ligand 10 0.344941
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.342739
MSLNL mesothelin-like 0.342006
SFTPA1 surfactant protein A1 0.335412
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.33066
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.327375
GPC4 glypican 4 0.325552
MT4 metallothionein 4 0.317909
JAK3 Janus kinase 3 0.312464
MMP1 matrix metallopeptidase 1 0.301615
CCL20 chemokine (C-C motif) ligand 20 0.300173
IL11RA interleukin 11 receptor, alpha 0.294053
ACAN aggrecan 0.293334
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.292975
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.287593
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.283655
KLK8 kallikrein-related peptidase 8 0.272953
ELOVL6 ELOVL fatty acid elongase 6 0.270464
NUP62 nucleoporin 62kDa 0.270108
TLR2 toll-like receptor 2 0.267267
MTX3 metaxin 3 0.264077
TYK2 tyrosine kinase 2 0.254888
ANGPT2 angiopoietin 2 0.253831
ICAM1 intercellular adhesion molecule 1 0.249257
JCHAIN joining chain of multimeric IgA and IgM 0.24715
MATN3 matrilin 3 0.246799
IFIH1 interferon induced with helicase C domain 1 0.241196
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 0.23945
LYZ lysozyme 0.23945
RAB4A RAB4A, member RAS oncogene family 0.237009
CCL21 chemokine (C-C motif) ligand 21 0.233183
TARS threonyl-tRNA synthetase 0.227642
FLG filaggrin 0.226952
CD80 CD80 molecule 0.226952
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.22145
CXCL8 chemokine (C-X-C motif) ligand 8 0.220081
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 0.218374
KLK1 kallikrein 1 0.217693
PRL prolactin 0.217352
TIMP1 TIMP metallopeptidase inhibitor 1 0.216332
GJB2 gap junction protein, beta 2, 26kDa 0.214975
IFNA1 interferon, alpha 1 0.213283
SST somatostatin 0.211597
FN1 fibronectin 1 0.20658
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.200331
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 0.197099
KLK13 kallikrein-related peptidase 13 0.196459
SPINK5 serine peptidase inhibitor, Kazal type 5 0.195501
CXCL9 chemokine (C-X-C motif) ligand 9 0.1936
IRAK1 interleukin-1 receptor-associated kinase 1 0.192657
IL23A interleukin 23, alpha subunit p19 0.184424
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.183835
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.183541
C7ORF49 chromosome 7 open reading frame 49 0.183541
MEFV Mediterranean fever 0.182957
PRTN3 proteinase 3 0.181222
CD8B CD8b molecule 0.177851
CSF1R colony stimulating factor 1 receptor 0.175679
CCL2 chemokine (C-C motif) ligand 2 0.173832
TLR4 toll-like receptor 4 0.171785
BGLAP bone gamma-carboxyglutamate (gla) protein 0.170544
SDC3 syndecan 3 0.170299
AGK acylglycerol kinase 0.169812
NCAM1 neural cell adhesion molecule 1 0.169571
PTTG1 pituitary tumor-transforming 1 0.169571
RUNX1 runt-related transcription factor 1 0.16933
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.16933
FGF1 fibroblast growth factor 1 (acidic) 0.167915
KLK6 kallikrein-related peptidase 6 0.167452
FOXP3 forkhead box P3 0.163938
STIP1 stress-induced phosphoprotein 1 0.163729
CXCR3 chemokine (C-X-C motif) receptor 3 0.161716
NOD1 nucleotide-binding oligomerization domain containing 1 0.158951
TTK TTK protein kinase 0.158434
VCAM1 vascular cell adhesion molecule 1 0.157929