proton-transporting two-sector atpase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. (Gene Ontology, GO_0016469)
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43 proteins co-occuring with the proton-transporting two-sector atpase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 1.03579
DNAH8 dynein, axonemal, heavy chain 8 0.947333
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.913443
AURKAIP1 aurora kinase A interacting protein 1 0.884244
FAF2 Fas associated factor family member 2 0.76726
PDCL3 phosducin-like 3 0.73287
MGAM maltase-glucoamylase 0.707039
VIT vitrin 0.706598
TMEM70 transmembrane protein 70 0.65388
NCF4 neutrophil cytosolic factor 4, 40kDa 0.628613
ATP11A ATPase, class VI, type 11A 0.612048
BFSP2 beaded filament structural protein 2, phakinin 0.497015
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.485693
SFTPA1 surfactant protein A1 0.477233
TXN thioredoxin 0.462398
EIF5A eukaryotic translation initiation factor 5A 0.447259
SLPI secretory leukocyte peptidase inhibitor 0.440916
CCL19 chemokine (C-C motif) ligand 19 0.388523
NNT nicotinamide nucleotide transhydrogenase 0.376202
PER1 period circadian clock 1 0.367771
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.365859
FBN2 fibrillin 2 0.365477
MCOLN1 mucolipin 1 0.359752
ZBTB16 zinc finger and BTB domain containing 16 0.321575
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.292157
IRF6 interferon regulatory factor 6 0.287352
SPX spexin hormone 0.27998
F9 coagulation factor IX 0.270434
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.250026
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.23776
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.236324
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.235966
OTC ornithine carbamoyltransferase 0.228464
SRSF1 serine/arginine-rich splicing factor 1 0.220673
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.218914
FTL ferritin, light polypeptide 0.209169
FTH1 ferritin, heavy polypeptide 1 0.207451
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.201335
HCRT hypocretin (orexin) neuropeptide precursor 0.183025
FBP1 fructose-1,6-bisphosphatase 1 0.173543
MT-ATP8 ATP synthase F0 subunit 8 0.172201
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.16477
TRH thyrotropin-releasing hormone 0.139222