protein tyrosine kinase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. (Gene Ontology, GO_0004713)
External Link http://amigo.geneontology.org/amigo/term/GO:0004713
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Genes

142 genes performing the protein tyrosine kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALK anaplastic lymphoma receptor tyrosine kinase
AXL AXL receptor tyrosine kinase
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCR breakpoint cluster region
BLK BLK proto-oncogene, Src family tyrosine kinase
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CLK1 CDC-like kinase 1
CLK2 CDC-like kinase 2
CLK3 CDC-like kinase 3
CLK4 CDC-like kinase 4
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DSTYK dual serine/threonine and tyrosine protein kinase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHA1 EPH receptor A1
EPHA10 EPH receptor A10
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EPHA6 EPH receptor A6
EPHA7 EPH receptor A7
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
EPHB4 EPH receptor B4
EPHB6 EPH receptor B6
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGFRL1 fibroblast growth factor receptor-like 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FRK fyn-related Src family tyrosine kinase
FYN FYN proto-oncogene, Src family tyrosine kinase
HCK HCK proto-oncogene, Src family tyrosine kinase
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
INSR insulin receptor
INSRR insulin receptor-related receptor
ITK IL2-inducible T-cell kinase
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
KIAA1804 mixed lineage kinase 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LTK leukocyte receptor tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MATK megakaryocyte-associated tyrosine kinase
MELK maternal embryonic leucine zipper kinase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MST1R macrophage stimulating 1 receptor
MUSK muscle, skeletal, receptor tyrosine kinase
NEK1 NIMA-related kinase 1
NPTN neuroplastin
NRP1 neuropilin 1
NRP2 neuropilin 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDGFRL platelet-derived growth factor receptor-like
PEAK1 pseudopodium-enriched atypical kinase 1
PKDCC protein kinase domain containing, cytoplasmic
PRKCD protein kinase C, delta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTK7 protein tyrosine kinase 7 (inactive)
RET ret proto-oncogene
RIPK2 receptor-interacting serine-threonine kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RYK receptor-like tyrosine kinase
SCYL1 SCY1-like 1 (S. cerevisiae)
SGK223 homolog of rat pragma of Rnd2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STK16 serine/threonine kinase 16
STYK1 serine/threonine/tyrosine kinase 1
SYK spleen tyrosine kinase
TEC tec protein tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TESK1 testis-specific kinase 1
TESK2 testis-specific kinase 2
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TNK1 tyrosine kinase, non-receptor, 1
TNK2 tyrosine kinase, non-receptor, 2
TRIM27 tripartite motif containing 27
TTK TTK protein kinase
TTN titin
TWF1 twinfilin actin binding protein 1
TXK TXK tyrosine kinase
TYK2 tyrosine kinase 2
TYRO3 TYRO3 protein tyrosine kinase
WEE1 WEE1 G2 checkpoint kinase
WEE2 WEE1 homolog 2 (S. pombe)
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa