protein serine/threonine kinase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. (Gene Ontology, GO_0004674)
External Link http://amigo.geneontology.org/amigo/term/GO:0004674
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Genes

429 genes performing the protein serine/threonine kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
AAK1 AP2 associated kinase 1
AATK apoptosis-associated tyrosine kinase
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADCK1 aarF domain containing kinase 1
ADCK2 aarF domain containing kinase 2
ADCK4 aarF domain containing kinase 4
ADCK5 aarF domain containing kinase 5
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK1 alpha-kinase 1
ALPK2 alpha-kinase 2
ALPK3 alpha-kinase 3
AMHR2 anti-Mullerian hormone receptor, type II
ANKK1 ankyrin repeat and kinase domain containing 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
BCKDK branched chain ketoacid dehydrogenase kinase
BCR breakpoint cluster region
BMP2K BMP2 inducible kinase
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAB39 calcium binding protein 39
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCL3 chemokine (C-C motif) ligand 3
CCND3 cyclin D3
CCNH cyclin H
CCNK cyclin K
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC7 cell division cycle 7
CDK1 cyclin-dependent kinase 1
CDK10 cyclin-dependent kinase 10
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK12 cyclin-dependent kinase 12
CDK13 cyclin-dependent kinase 13
CDK14 cyclin-dependent kinase 14
CDK15 cyclin-dependent kinase 15
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK19 cyclin-dependent kinase 19
CDK2 cyclin-dependent kinase 2
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CDKL3 cyclin-dependent kinase-like 3
CDKL4 cyclin-dependent kinase-like 4
CDKL5 cyclin-dependent kinase-like 5
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CIT citron rho-interacting serine/threonine kinase
CLK1 CDC-like kinase 1
CLK2 CDC-like kinase 2
CLK3 CDC-like kinase 3
CLK4 CDC-like kinase 4
CPNE3 copine III
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CSNK2B casein kinase 2, beta polypeptide
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DCLK1 doublecortin-like kinase 1
DCLK2 doublecortin-like kinase 2
DCLK3 doublecortin-like kinase 3
DCX doublecortin
DMPK dystrophia myotonica-protein kinase
DSTYK dual serine/threonine and tyrosine protein kinase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM20C family with sequence similarity 20, member C
FASTK Fas-activated serine/threonine kinase
GAK cyclin G associated kinase
GRK1 G protein-coupled receptor kinase 1
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GRK7 G protein-coupled receptor kinase 7
GSG2 germ cell associated 2 (haspin)
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
HIPK3 homeodomain interacting protein kinase 3
HIPK4 homeodomain interacting protein kinase 4
HMGA2 high mobility group AT-hook 2
HUNK hormonally up-regulated Neu-associated kinase
ICK intestinal cell (MAK-like) kinase
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ILK integrin-linked kinase
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKA inositol-trisphosphate 3-kinase A
KALRN kalirin, RhoGEF kinase
KIAA1804 mixed lineage kinase 4
KSR1 kinase suppressor of ras 1
KSR2 kinase suppressor of ras 2
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LMTK2 lemur tyrosine kinase 2
LMTK3 lemur tyrosine kinase 3
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LTBP1 latent transforming growth factor beta binding protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAK male germ cell-associated kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST1 microtubule associated serine/threonine kinase 1
MAST2 microtubule associated serine/threonine kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MASTL microtubule associated serine/threonine kinase-like
MELK maternal embryonic leucine zipper kinase
MINK1 misshapen-like kinase 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOK MOK protein kinase
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYLK myosin light chain kinase
MYLK2 myosin light chain kinase 2
MYLK3 myosin light chain kinase 3
MYLK4 myosin light chain kinase family, member 4
MYO3A myosin IIIA
MYO3B myosin IIIB
NEK1 NIMA-related kinase 1
NEK10 NIMA-related kinase 10
NEK11 NIMA-related kinase 11
NEK2 NIMA-related kinase 2
NEK3 NIMA-related kinase 3
NEK4 NIMA-related kinase 4
NEK5 NIMA-related kinase 5
NEK6 NIMA-related kinase 6
NEK7 NIMA-related kinase 7
NEK8 NIMA-related kinase 8
NEK9 NIMA-related kinase 9
NEXN nexilin (F actin binding protein)
NIM1K NIM1 serine/threonine protein kinase
NLK nemo-like kinase
NRK Nik related kinase
NUAK1 NUAK family, SNF1-like kinase, 1
NUAK2 NUAK family, SNF1-like kinase, 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OXSR1 oxidative stress responsive 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PASK PAS domain containing serine/threonine kinase
PBK PDZ binding kinase
PDIK1L PDLIM1 interacting kinase 1 like
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHKB phosphorylase kinase, beta
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN1 protein kinase N1
PKN2 protein kinase N2
PKN3 protein kinase N3
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PPP4C protein phosphatase 4, catalytic subunit
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PRKX protein kinase, X-linked
PRPF4B pre-mRNA processing factor 4B
PSKH1 protein serine kinase H1
PSKH2 protein serine kinase H2
PTK2B protein tyrosine kinase 2 beta
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RIOK1 RIO kinase 1
RIOK2 RIO kinase 2
RIOK3 RIO kinase 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RPS6KL1 ribosomal protein S6 kinase-like 1
SBK1 SH3 domain binding kinase 1
SBK2 SH3 domain binding kinase family, member 2
SBK3 SH3 domain binding kinase family, member 3
SGK1 serum/glucocorticoid regulated kinase 1
SGK2 serum/glucocorticoid regulated kinase 2
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SLK STE20-like kinase
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNRK SNF related kinase
SNX15 sorting nexin 15
SPEG SPEG complex locus
SQSTM1 sequestosome 1
SRPK1 SRSF protein kinase 1
SRPK2 SRSF protein kinase 2
SRPK3 SRSF protein kinase 3
STK10 serine/threonine kinase 10
STK11 serine/threonine kinase 11
STK16 serine/threonine kinase 16
STK17A serine/threonine kinase 17a
STK17B serine/threonine kinase 17b
STK19 serine/threonine kinase 19
STK24 serine/threonine kinase 24
STK25 serine/threonine kinase 25
STK26 serine/threonine protein kinase 26
STK3 serine/threonine kinase 3
STK31 serine/threonine kinase 31
STK32A serine/threonine kinase 32A
STK32B serine/threonine kinase 32B
STK32C serine/threonine kinase 32C
STK33 serine/threonine kinase 33
STK35 serine/threonine kinase 35
STK36 serine/threonine kinase 36
STK38 serine/threonine kinase 38
STK38L serine/threonine kinase 38 like
STK39 serine threonine kinase 39
STK4 serine/threonine kinase 4
STK40 serine/threonine kinase 40
STRADA STE20-related kinase adaptor alpha
STRADB STE20-related kinase adaptor beta
SYK spleen tyrosine kinase
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TBK1 TANK-binding kinase 1
TESK1 testis-specific kinase 1
TESK2 testis-specific kinase 2
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TLK1 tousled-like kinase 1
TLK2 tousled-like kinase 2
TNIK TRAF2 and NCK interacting kinase
TNK2 tyrosine kinase, non-receptor, 2
TP53RK TP53 regulating kinase
TRIO trio Rho guanine nucleotide exchange factor
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSSK1B testis-specific serine kinase 1B
TSSK2 testis-specific serine kinase 2
TSSK3 testis-specific serine kinase 3
TSSK4 testis-specific serine kinase 4
TSSK6 testis-specific serine kinase 6
TTBK1 tau tubulin kinase 1
TTBK2 tau tubulin kinase 2
TTK TTK protein kinase
TTN titin
UHMK1 U2AF homology motif (UHM) kinase 1
ULK1 unc-51 like autophagy activating kinase 1
ULK2 unc-51 like autophagy activating kinase 2
ULK3 unc-51 like kinase 3
ULK4 unc-51 like kinase 4
VPRBP Vpr (HIV-1) binding protein
VRK1 vaccinia related kinase 1
VRK2 vaccinia related kinase 2
VRK3 vaccinia related kinase 3
WEE1 WEE1 G2 checkpoint kinase
WEE2 WEE1 homolog 2 (S. pombe)
WNK1 WNK lysine deficient protein kinase 1
WNK2 WNK lysine deficient protein kinase 2
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4
XRCC6BP1 XRCC6 binding protein 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK