protein processing Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. (Gene Ontology, GO_0016485)
External Link http://amigo.geneontology.org/amigo/term/GO:0016485
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Genes

205 genes participating in the protein processing biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACER2 alkaline ceramidase 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AFG3L2 AFG3-like AAA ATPase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANPEP alanyl (membrane) aminopeptidase
APAF1 apoptotic peptidase activating factor 1
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
APOH apolipoprotein H (beta-2-glycoprotein I)
ASPH aspartate beta-hydroxylase
ASPRV1 aspartic peptidase, retroviral-like 1
ATG4A autophagy related 4A, cysteine peptidase
ATG4B autophagy related 4B, cysteine peptidase
ATG4C autophagy related 4C, cysteine peptidase
ATG4D autophagy related 4D, cysteine peptidase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AZU1 azurocidin 1
BACE2 beta-site APP-cleaving enzyme 2
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BOK BCL2-related ovarian killer
C2CD3 C2 calcium-dependent domain containing 3
CAPN2 calpain 2, (m/II) large subunit
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCK cholecystokinin
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CIDEB cell death-inducing DFFA-like effector b
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN5 ceroid-lipofuscinosis, neuronal 5
CMA1 chymase 1, mast cell
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORIN corin, serine peptidase
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSE cathepsin E
CTSG cathepsin G
CTSH cathepsin H
CTSS cathepsin S
CTSV cathepsin V
CTSZ cathepsin Z
CUZD1 CUB and zona pellucida-like domains 1
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAP death-associated protein
DHCR24 24-dehydrocholesterol reductase
DIABLO diablo, IAP-binding mitochondrial protein
DLC1 DLC1 Rho GTPase activating protein
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECE1 endothelin converting enzyme 1
ECE2 endothelin converting enzyme 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERO1LB ERO1-like beta (S. cerevisiae)
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FKRP fukutin related protein
FSHB follicle stimulating hormone, beta polypeptide
FURIN furin (paired basic amino acid cleaving enzyme)
FXN frataxin
GGT1 gamma-glutamyltransferase 1
GLI3 GLI family zinc finger 3
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HIP1 huntingtin interacting protein 1
HIST1H2BA histone cluster 1, H2ba
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HTRA2 HtrA serine peptidase 2
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFT172 intraflagellar transport 172
IFT57 intraflagellar transport 57
IHH indian hedgehog
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
JAK2 Janus kinase 2
KLK13 kallikrein-related peptidase 13
KLK6 kallikrein-related peptidase 6
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LHB luteinizing hormone beta polypeptide
LONP2 lon peptidase 2, peroxisomal
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK9 mitogen-activated protein kinase 9
METAP2 methionyl aminopeptidase 2
MIPEP mitochondrial intermediate peptidase
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTCH1 mitochondrial carrier 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCSTN nicastrin
NGF nerve growth factor (beta polypeptide)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKX3-1 NK3 homeobox 1
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NMT2 N-myristoyltransferase 2
NOD1 nucleotide-binding oligomerization domain containing 1
OMA1 OMA1 zinc metallopeptidase
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARP1 poly (ADP-ribose) polymerase 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCSK2 proprotein convertase subtilisin/kexin type 2
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD2 programmed cell death 2
PDCD6 programmed cell death 6
PERP PERP, TP53 apoptosis effector
PIDD1 p53-induced death domain protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PLAT plasminogen activator, tissue
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS3 protease, serine, 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTCH1 patched 1
PTHLH parathyroid hormone-like hormone
PYCARD PYD and CARD domain containing
RCE1 Ras converting CAAX endopeptidase 1
REN renin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCG5 secretogranin V
SEC11A SEC11 homolog A (S. cerevisiae)
SEC11C SEC11 homolog C (S. cerevisiae)
SENP1 SUMO1/sentrin specific peptidase 1
SHH sonic hedgehog
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SRGN serglycin
STOML2 stomatin (EPB72)-like 2
TBC1D10A TBC1 domain family, member 10A
TMPRSS2 transmembrane protease, serine 2
TMPRSS9 transmembrane protease, serine 9
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TSG101 tumor susceptibility 101
TSHB thyroid stimulating hormone, beta
TYSND1 trypsin domain containing 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
USP17L2 ubiquitin specific peptidase 17-like family member 2
VCP valosin containing protein
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
XDH xanthine dehydrogenase
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMPSTE24 zinc metallopeptidase STE24