protein kinase binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. (Gene Ontology, GO_0019901)
External Link http://amigo.geneontology.org/amigo/term/GO:0019901
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Genes

435 genes performing the protein kinase binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACVRL1 activin A receptor type II-like 1
ADAM10 ADAM metallopeptidase domain 10
ADAM9 ADAM metallopeptidase domain 9
ADCY6 adenylate cyclase 6
ADIPOR1 adiponectin receptor 1
ADRA2A adrenoceptor alpha 2A
AKAP7 A kinase (PRKA) anchor protein 7
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANK2 ankyrin 2, neuronal
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APC adenomatous polyposis coli
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
ATF7 activating transcription factor 7
ATG13 autophagy related 13
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AURKA aurora kinase A
AVPR1A arginine vasopressin receptor 1A
AVPR1B arginine vasopressin receptor 1B
AXIN1 axin 1
AXIN2 axin 2
BAD BCL2-associated agonist of cell death
BAG5 BCL2-associated athanogene 5
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2L1 BCL2-like 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BORA bora, aurora kinase A activator
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
C1QBP complement component 1, q subcomponent binding protein
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACUL1 CDK2-associated, cullin domain 1
CADPS Ca++-dependent secretion activator
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC88A coiled-coil domain containing 88A
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNB3 cyclin B3
CCNC cyclin C
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNH cyclin H
CCNK cyclin K
CCNL1 cyclin L1
CCNL2 cyclin L2
CCNT1 cyclin T1
CCNT2 cyclin T2
CCNY cyclin Y
CCNYL1 cyclin Y-like 1
CD226 CD226 molecule
CD24 CD24 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD4 CD4 molecule
CD8A CD8a molecule
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPJ centromere protein J
CEP152 centrosomal protein 152kDa
CEP250 centrosomal protein 250kDa
CEP68 centrosomal protein 68kDa
CHEK2 checkpoint kinase 2
CLTC clathrin, heavy chain (Hc)
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTLN centlein, centrosomal protein
CRY1 cryptochrome circadian clock 1
CSPG4 chondroitin sulfate proteoglycan 4
CTNND1 catenin (cadherin-associated protein), delta 1
CYLD cylindromatosis (turban tumor syndrome)
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DACT3 dishevelled-binding antagonist of beta-catenin 3
DAXX death-domain associated protein
DBF4B DBF4 zinc finger B
DCX doublecortin
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIXDC1 DIX domain containing 1
DLG1 discs, large homolog 1 (Drosophila)
DNM1 dynamin 1
DOK7 docking protein 7
DPYSL2 dihydropyrimidinase-like 2
DSP desmoplakin
DUSP19 dual specificity phosphatase 19
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ELP2 elongator acetyltransferase complex subunit 2
EMP2 epithelial membrane protein 2
EPHA1 EPH receptor A1
ERRFI1 ERBB receptor feedback inhibitor 1
EXOC2 exocyst complex component 2
FAF1 Fas (TNFRSF6) associated factor 1
FAM58A family with sequence similarity 58, member A
FBXO5 F-box protein 5
FBXO7 F-box protein 7
FBXW5 F-box and WD repeat domain containing 5
FER fer (fps/fes related) tyrosine kinase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1OP FGFR1 oncogene partner
FGR FGR proto-oncogene, Src family tyrosine kinase
FLNA filamin A, alpha
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FZD5 frizzled class receptor 5
GATA6 GATA binding protein 6
GCSAM germinal center-associated, signaling and motility
GDF3 growth differentiation factor 3
GHR growth hormone receptor
GLRX3 glutaredoxin 3
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOLGA2 golgin A2
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GRK5 G protein-coupled receptor kinase 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GTF2I general transcription factor IIi
GYS1 glycogen synthase 1 (muscle)
H2AFY H2A histone family, member Y
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HINT1 histidine triad nucleotide binding protein 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB1 heat shock 27kDa protein 1
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFNAR2 interferon (alpha, beta and omega) receptor 2
IGBP1 immunoglobulin (CD79A) binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL12RB2 interleukin 12 receptor, beta 2
IL31RA interleukin 31 receptor A
ILK integrin-linked kinase
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JTB jumping translocation breakpoint
JUP junction plakoglobin
KAT2B K(lysine) acetyltransferase 2B
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF11 kinesin family member 11
KIF13B kinesin family member 13B
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIZ kizuna centrosomal protein
KSR1 kinase suppressor of ras 1
LAT linker for activation of T cells
LATS1 large tumor suppressor kinase 1
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LDB3 LIM domain binding 3
LIMS1 LIM and senescent cell antigen-like domains 1
LIPE lipase, hormone-sensitive
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAML1 mastermind-like 1 (Drosophila)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK4 mitogen-activated protein kinase 4
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPK9 mitogen-activated protein kinase 9
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MARVELD3 MARVEL domain containing 3
MAVS mitochondrial antiviral signaling protein
MEF2A myocyte enhancer factor 2A
MICALCL MICAL C-terminal like
MLKL mixed lineage kinase domain-like
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSH2 mutS homolog 2
MSN moesin
MVP major vault protein
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NBEA neurobeachin
NBR1 neighbor of BRCA1 gene 1
NCS1 neuronal calcium sensor 1
NEFH neurofilament, heavy polypeptide
NEK6 NIMA-related kinase 6
NEK9 NIMA-related kinase 9
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NSF N-ethylmaleimide-sensitive factor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARD3 par-3 family cell polarity regulator
PARD6A par-6 family cell polarity regulator alpha
PARK2 parkin RBR E3 ubiquitin protein ligase
PARN poly(A)-specific ribonuclease
PARP1 poly (ADP-ribose) polymerase 1
PAX6 paired box 6
PDCD10 programmed cell death 10
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM5 PDZ and LIM domain 5
PDPK1 3-phosphoinositide dependent protein kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGAM1 phosphoglycerate mutase 1 (brain)
PICK1 protein interacting with PRKCA 1
PIFO primary cilia formation
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PIWIL1 piwi-like RNA-mediated gene silencing 1
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKN1 protein kinase N1
PKP2 plakophilin 2
PLCG1 phospholipase C, gamma 1
PLEK pleckstrin
PLK1 polo-like kinase 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRC1 protein regulator of cytokinesis 1
PRDX3 peroxiredoxin 3
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PRKCDBP protein kinase C, delta binding protein
PRKCSH protein kinase C substrate 80K-H
PRKCZ protein kinase C, zeta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRR protein tyrosine phosphatase, receptor type, R
PXN paxillin
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB13 RAB13, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARA retinoic acid receptor, alpha
RB1CC1 RB1-inducible coiled-coil 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RGCC regulator of cell cycle
RGS14 regulator of G-protein signaling 14
RHEB Ras homolog enriched in brain
RHOD ras homolog family member D
RICTOR RPTOR independent companion of MTOR, complex 2
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RPS19 ribosomal protein S19
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPTOR regulatory associated protein of MTOR, complex 1
RYR2 ryanodine receptor 2 (cardiac)
SASH1 SAM and SH3 domain containing 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC4 syndecan 4
SDPR serum deprivation response
SFN stratifin
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHC4 SHC (Src homology 2 domain containing) family, member 4
SIRT1 sirtuin 1
SKAP1 src kinase associated phosphoprotein 1
SKI SKI proto-oncogene
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC22A8 solute carrier family 22 (organic anion transporter), member 8
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SNAP91 synaptosomal-associated protein, 91kDa
SOCS1 suppressor of cytokine signaling 1
SORBS1 sorbin and SH3 domain containing 1
SOX9 SRY (sex determining region Y)-box 9
SPAG16 sperm associated antigen 16
SPAG9 sperm associated antigen 9
SPDYA speedy/RINGO cell cycle regulator family member A
SPDYC speedy/RINGO cell cycle regulator family member C
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCIN1 SRC kinase signaling inhibitor 1
SREBF1 sterol regulatory element binding transcription factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11IP serine/threonine kinase 11 interacting protein
STK38 serine/threonine kinase 38
STK39 serine threonine kinase 39
STX17 syntaxin 17
STX1B syntaxin 1B
STXBP1 syntaxin binding protein 1
SUFU suppressor of fused homolog (Drosophila)
SV2A synaptic vesicle glycoprotein 2A
SYK spleen tyrosine kinase
SYN1 synapsin I
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK2 TAO kinase 2
TBC1D14 TBC1 domain family, member 14
TBL2 transducin (beta)-like 2
TCF3 transcription factor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDG thymine-DNA glycosylase
TEX14 testis expressed 14
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TMEM173 transmembrane protein 173
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNNI3 troponin I type 3 (cardiac)
TOM1L1 target of myb1 (chicken)-like 1
TOM1L2 target of myb1-like 2 (chicken)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP73 tumor protein p73
TPCN2 two pore segment channel 2
TPR translocated promoter region, nuclear basket protein
TPRKB TP53RK binding protein
TPX2 TPX2, microtubule-associated
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF4 TNF receptor-associated factor 4
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAP1 TNF receptor-associated protein 1
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSKS testis-specific serine kinase substrate
TTN titin
TWF2 twinfilin actin binding protein 2
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
ULK1 unc-51 like autophagy activating kinase 1
USF1 upstream transcription factor 1
USP37 ubiquitin specific peptidase 37
UTRN utrophin
VDAC1 voltage-dependent anion channel 1
WAS Wiskott-Aldrich syndrome
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB4 zinc finger and BTB domain containing 4
ZC3HC1 zinc finger, C3HC-type containing 1
ZFP36 ZFP36 ring finger protein