protein k63-linked ubiquitination Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair. (Gene Ontology, GO_0070534)
External Link http://amigo.geneontology.org/amigo/term/GO:0070534
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Genes

32 genes participating in the protein k63-linked ubiquitination biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BFAR bifunctional apoptosis regulator
ITCH itchy E3 ubiquitin protein ligase
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
PARK2 parkin RBR E3 ubiquitin protein ligase
PELI3 pellino E3 ubiquitin protein ligase family member 3
PRPF19 pre-mRNA processing factor 19
RNF115 ring finger protein 115
RNF126 ring finger protein 126
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM27 tripartite motif containing 27
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2N ubiquitin-conjugating enzyme E2N
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UBE2S ubiquitin-conjugating enzyme E2S
UBE2T ubiquitin-conjugating enzyme E2T
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFP91 ZFP91 zinc finger protein