protein k48-linked ubiquitination Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. (Gene Ontology, GO_0070936)
External Link http://amigo.geneontology.org/amigo/term/GO:0070936
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Genes

45 genes participating in the protein k48-linked ubiquitination biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BFAR bifunctional apoptosis regulator
CDC34 cell division cycle 34
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
ITCH itchy E3 ubiquitin protein ligase
KLHL3 kelch-like family member 3
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PARK2 parkin RBR E3 ubiquitin protein ligase
PELI1 pellino E3 ubiquitin protein ligase 1
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RNF115 ring finger protein 115
RNF126 ring finger protein 126
RNF146 ring finger protein 146
RNF152 ring finger protein 152
RNF187 ring finger protein 187
RNF216 ring finger protein 216
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM38 tripartite motif containing 38
TTC3 tetratricopeptide repeat domain 3
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2K ubiquitin-conjugating enzyme E2K
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2T ubiquitin-conjugating enzyme E2T
UBE3A ubiquitin protein ligase E3A
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase