protein heterodimerization activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. (Gene Ontology, GO_0046982)
External Link http://amigo.geneontology.org/amigo/term/GO:0046982
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Genes

386 genes performing the protein heterodimerization activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADCY2 adenylate cyclase 2 (brain)
ADCY5 adenylate cyclase 5
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADORA1 adenosine A1 receptor
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALX1 ALX homeobox 1
ALX4 ALX homeobox 4
ANO1 anoctamin 1, calcium activated chloride channel
ANO2 anoctamin 2, calcium activated chloride channel
AOC3 amine oxidase, copper containing 3
APOA2 apolipoprotein A-II
ARNT aryl hydrocarbon receptor nuclear translocator
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BDKRB2 bradykinin receptor B2
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD11 BTB (POZ) domain containing 11
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPN2 calpain 2, (m/II) large subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CENPA centromere protein A
CENPT centromere protein T
CENPW centromere protein W
CHRAC1 chromatin accessibility complex 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLCF1 cardiotrophin-like cytokine factor 1
CLCN3 chloride channel, voltage-sensitive 3
CLNS1A chloride channel, nucleotide-sensitive, 1A
CREB3L3 cAMP responsive element binding protein 3-like 3
CRLF1 cytokine receptor-like factor 1
CUL3 cullin 3
CUL5 cullin 5
CXCL13 chemokine (C-X-C motif) ligand 13
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DDIT3 DNA-damage-inducible transcript 3
DGKD diacylglycerol kinase, delta 130kDa
DLK2 delta-like 2 homolog (Drosophila)
DMBX1 diencephalon/mesencephalon homeobox 1
DMRT1 doublesex and mab-3 related transcription factor 1
DMRT3 doublesex and mab-3 related transcription factor 3
DMRTA2 DMRT-like family A2
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRD2 dopamine receptor D2
DVL3 dishevelled segment polarity protein 3
EGFR epidermal growth factor receptor
ENO3 enolase 3 (beta, muscle)
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FOXP2 forkhead box P2
FOXP4 forkhead box P4
FZD4 frizzled class receptor 4
FZD9 frizzled class receptor 9
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GABPB2 GA binding protein transcription factor, beta subunit 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCA grancalcin, EF-hand calcium binding protein
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2A2 general transcription factor IIA, 2, 12kDa
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUCY2F guanylate cyclase 2F, retinal
H2AFB1 H2A histone family, member B1
H2AFJ H2A histone family, member J
H2AFV H2A histone family, member V
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
H2AFY2 H2A histone family, member Y2
H2AFZ H2A histone family, member Z
H2BFM H2B histone family, member M
H2BFWT H2B histone family, member W, testis-specific
H3F3C H3 histone, family 3C
HAND1 heart and neural crest derivatives expressed 1
HAND2 heart and neural crest derivatives expressed 2
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H2AA histone cluster 1, H2aa
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H2BD histone cluster 1, H2bd
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H4G histone cluster 1, H4g
HIST2H2AB histone cluster 2, H2ab
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST2H2BF histone cluster 2, H2bf
HIST3H2A histone cluster 3, H2a
HIST3H2BB histone cluster 3, H2bb
HIST3H3 histone cluster 3, H3
HMG20A high mobility group 20A
HMG20B high mobility group 20B
HNF1B HNF1 homeobox B
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HYPM huntingtin interacting protein M
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF2 IKAROS family zinc finger 2 (Helios)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IKZF4 IKAROS family zinc finger 4 (Eos)
IL12A interleukin 12A
IL12B interleukin 12B
INHA inhibin, alpha
INHBA inhibin, beta A
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA7 integrin, alpha 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAM2 junctional adhesion molecule 2
JAM3 junctional adhesion molecule 3
JDP2 Jun dimerization protein 2
KATNA1 katanin p60 (ATPase containing) subunit A 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNIP1 Kv channel interacting protein 1
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LOC102724334 histone H2B type F-S-like
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAPK4 mitogen-activated protein kinase 4
MAPK6 mitogen-activated protein kinase 6
MAX MYC associated factor X
MCL1 myeloid cell leukemia 1
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MEIS1 Meis homeobox 1
MICU1 mitochondrial calcium uptake 1
MICU2 mitochondrial calcium uptake 2
MID1 midline 1
MID2 midline 2
MLX MLX, MAX dimerization protein
MLXIPL MLX interacting protein-like
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MYF5 myogenic factor 5
MYF6 myogenic factor 6 (herculin)
MYOD1 myogenic differentiation 1
MYOG myogenin (myogenic factor 4)
NAE1 NEDD8 activating enzyme E1 subunit 1
NEUROD1 neuronal differentiation 1
NEUROD2 neuronal differentiation 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
NKX2-5 NK2 homeobox 5
NOTCH4 notch 4
NPAS4 neuronal PAS domain protein 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
OTX2 orthodenticle homeobox 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PANX1 pannexin 1
PBX1 pre-B-cell leukemia homeobox 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDX1 pancreatic and duodenal homeobox 1
PEF1 penta-EF-hand domain containing 1
PGF placental growth factor
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKNOX1 PBX/knotted 1 homeobox 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRMT5 protein arginine methyltransferase 5
PRMT8 protein arginine methyltransferase 8
PVALB parvalbumin
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RARA retinoic acid receptor, alpha
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROPN1B rhophilin associated tail protein 1B
RRAGA Ras-related GTP binding A
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
RXRA retinoid X receptor, alpha
SAE1 SUMO1 activating enzyme subunit 1
SCGB1D1 secretoglobin, family 1D, member 1
SCGB2A1 secretoglobin, family 2A, member 1
SCUBE1 signal peptide, CUB domain, EGF-like 1
SCX scleraxis basic helix-loop-helix transcription factor
SDCBP syndecan binding protein (syntenin)
SDCBP2 syndecan binding protein (syntenin) 2
SIM1 single-minded family bHLH transcription factor 1
SIM2 single-minded family bHLH transcription factor 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC51A solute carrier family 51, alpha subunit
SLC51B solute carrier family 51, beta subunit
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SOX14 SRY (sex determining region Y)-box 14
SOX15 SRY (sex determining region Y)-box 15
SOX17 SRY (sex determining region Y)-box 17
SOX18 SRY (sex determining region Y)-box 18
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX5 SRY (sex determining region Y)-box 5
SOX6 SRY (sex determining region Y)-box 6
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTB spectrin, beta, erythrocytic
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C
SRI sorcin
ST20 suppressor of tumorigenicity 20
STX1A syntaxin 1A (brain)
SUCLG1 succinate-CoA ligase, alpha subunit
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYCP2 synaptonemal complex protein 2
SYT10 synaptotagmin X
SYT14 synaptotagmin XIV
SYT16 synaptotagmin XVI
SYT5 synaptotagmin V
SYT6 synaptotagmin VI
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAL1 T-cell acute lymphocytic leukemia 1
TAS1R1 taste receptor, type 1, member 1
TAS1R2 taste receptor, type 1, member 2
TAS1R3 taste receptor, type 1, member 3
TBX15 T-box 15
TBX18 T-box 18
TCF12 transcription factor 12
TCF3 transcription factor 3
TCF4 transcription factor 4
TEF thyrotrophic embryonic factor
TENM1 teneurin transmembrane protein 1
TENM3 teneurin transmembrane protein 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP3 transcription factor Dp family, member 3
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TIMELESS timeless circadian clock
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR6 toll-like receptor 6
TLX1 T-cell leukemia homeobox 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TSC2 tuberous sclerosis 2
TTR transthyretin
TWIST1 twist family bHLH transcription factor 1
TXLNG taxilin gamma
TYR tyrosinase
TYRO3 TYRO3 protein tyrosine kinase
TYRP1 tyrosinase-related protein 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBA3 ubiquitin-like modifier activating enzyme 3
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
XBP1 X-box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB1 zinc finger and BTB domain containing 1
ZHX1 zinc fingers and homeoboxes 1
ZHX2 zinc fingers and homeoboxes 2
ZHX3 zinc fingers and homeoboxes 3