protein binding, bridging Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. (Gene Ontology, GO_0030674)
External Link http://amigo.geneontology.org/amigo/term/GO:0030674
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Genes

134 genes performing the protein binding, bridging molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ABI2 abl-interactor 2
ADAP2 ArfGAP with dual PH domains 2
ANK1 ankyrin 1, erythrocytic
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA1 annexin A1
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGAP1 Rho GTPase activating protein 1
ARHGAP4 Rho GTPase activating protein 4
ARHGAP6 Rho GTPase activating protein 6
BAIAP2 BAI1-associated protein 2
BCL3 B-cell CLL/lymphoma 3
BICD1 bicaudal D homolog 1 (Drosophila)
BIN3 bridging integrator 3
BLNK B-cell linker
CBX5 chromobox homolog 5
CD28 CD28 molecule
CHN1 chimerin 1
CHN2 chimerin 2
CLNK cytokine-dependent hematopoietic cell linker
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNTLN centlein, centrosomal protein
CNTNAP1 contactin associated protein 1
COL11A1 collagen, type XI, alpha 1
COL11A2 collagen, type XI, alpha 2
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL1A2 collagen, type I, alpha 2
COL8A2 collagen, type VIII, alpha 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSTA cystatin A (stefin A)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DOK2 docking protein 2, 56kDa
DSP desmoplakin
EPS8 epidermal growth factor receptor pathway substrate 8
EVPL envoplakin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCRL2 Fc receptor-like 2
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP4 FK506 binding protein 4, 59kDa
FLRT1 fibronectin leucine rich transmembrane protein 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FRMD4A FERM domain containing 4A
FRS2 fibroblast growth factor receptor substrate 2
FSCN1 fascin actin-bundling protein 1
FSCN2 fascin actin-bundling protein 2, retinal
FSCN3 fascin actin-bundling protein 3, testicular
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAS2L1 growth arrest-specific 2 like 1
GATAD2A GATA zinc finger domain containing 2A
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HSH2D hematopoietic SH2 domain containing
IRS1 insulin receptor substrate 1
IRS4 insulin receptor substrate 4
ITSN2 intersectin 2
IVL involucrin
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LASP1 LIM and SH3 protein 1
LAT linker for activation of T cells
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LOR loricrin
MEN1 multiple endocrine neoplasia I
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NEFH neurofilament, heavy polypeptide
NEFL neurofilament, light polypeptide
NMD3 NMD3 ribosome export adaptor
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OBSL1 obscurin-like 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPP4R2 protein phosphatase 4, regulatory subunit 2
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD50 RAD50 homolog (S. cerevisiae)
RUSC1 RUN and SH3 domain containing 1
SDCBP syndecan binding protein (syntenin)
SH2B2 SH2B adaptor protein 2
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SH2D3C SH2 domain containing 3C
SH3BGR SH3 domain binding glutamate-rich protein
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3BP2 SH3-domain binding protein 2
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKAP1 src kinase associated phosphoprotein 1
SKAP2 src kinase associated phosphoprotein 2
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOCS2 suppressor of cytokine signaling 2
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAP1 signal transducing adaptor family member 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX1A syntaxin 1A (brain)
TCAP titin-cap
TEX261 testis expressed 261
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TJP2 tight junction protein 2
TOB1 transducer of ERBB2, 1
TP53BP2 tumor protein p53 binding protein 2
TRAT1 T cell receptor associated transmembrane adaptor 1
TRDN triadin
VAV3 vav 3 guanine nucleotide exchange factor
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
WWC1 WW and C2 domain containing 1