protein activation cascade Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events. (Gene Ontology, GO_0072376)
External Link http://amigo.geneontology.org/amigo/term/GO:0072376
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Genes

63 genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
APOH apolipoprotein H (beta-2-glycoprotein I)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR5 complement factor H-related 5
CFI complement factor I
CFP complement factor properdin
CLU clusterin
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
F10 coagulation factor X
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGA fibrinogen alpha chain
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP9 glycoprotein IX (platelet)
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KNG1 kininogen 1
KRT1 keratin 1, type II
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MVP major vault protein
PRCP prolylcarboxypeptidase (angiotensinase C)
RGCC regulator of cell cycle
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SUSD4 sushi domain containing 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor