proteasome core complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. (Gene Ontology, GO_0005839)
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221 proteins co-occuring with the proteasome core complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CTRL chymotrypsin-like 2.958
POMP proteasome maturation protein 1.83679
PSME4 proteasome (prosome, macropain) activator subunit 4 1.67143
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.62886
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.57932
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.52428
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 1.44629
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.39461
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.33142
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.30282
UBE2H ubiquitin-conjugating enzyme E2H 1.30228
PAAF1 proteasomal ATPase-associated factor 1 1.2455
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.22776
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.22568
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.22412
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.22049
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.21428
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.20705
ADRM1 adhesion regulating molecule 1 1.18389
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.16338
DCD dermcidin 1.11633
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.07613
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.06498
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 1.05791
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.05539
HLA-B major histocompatibility complex, class I, B 1.03378
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 1.00251
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.993183
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.983419
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.95305
CAPN2 calpain 2, (m/II) large subunit 0.944007
DNAH8 dynein, axonemal, heavy chain 8 0.934072
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.918579
C1ORF68 chromosome 1 open reading frame 68 0.917177
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.912045
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.887936
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.887474
CSN1S1 casein alpha s1 0.849287
THRB thyroid hormone receptor, beta 0.825877
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.817158
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 0.813946
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11 0.79927
HYKK hydroxylysine kinase 0.782326
FBXO32 F-box protein 32 0.779126
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.772732
ZPBP2 zona pellucida binding protein 2 0.767715
HSPA4 heat shock 70kDa protein 4 0.742769
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.738263
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.728389
MRPL19 mitochondrial ribosomal protein L19 0.718125
ASB10 ankyrin repeat and SOCS box containing 10 0.710136
TP53 tumor protein p53 0.695587
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.69427
UBL3 ubiquitin-like 3 0.679849
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 0.648291
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.634159
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.62393
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.617982
BLMH bleomycin hydrolase 0.614165
CTSB cathepsin B 0.605284
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.594753
GSDMA gasdermin A 0.590553
PUS10 pseudouridylate synthase 10 0.590133
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.573828
LAP3 leucine aminopeptidase 3 0.573411
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 0.572578
ODC1 ornithine decarboxylase 1 0.561358
UBAC1 UBA domain containing 1 0.556387
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.548947
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 0.545236
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.541529
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.538238
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.537416
LYZ lysozyme 0.535361
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.532898
WBSCR22 Williams Beuren syndrome chromosome region 22 0.532078
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.529208
TRIM13 tripartite motif containing 13 0.525931
T T, brachyury homolog (mouse) 0.524704
HSPA8 heat shock 70kDa protein 8 0.520615
MOCOS molybdenum cofactor sulfurase 0.504724
GSDMB gasdermin B 0.491348
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.488519
USP2 ubiquitin specific peptidase 2 0.4865
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.484886
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.484079
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.479647
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.476027
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.470807
UBQLN4 ubiquilin 4 0.469203
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.463598
YIPF1 Yip1 domain family, member 1 0.461599
FBXO25 F-box protein 25 0.458404
MSRA methionine sulfoxide reductase A 0.454019
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.448848
UBB ubiquitin B 0.4425
CSN2 casein beta 0.427104
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.421212
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.414946
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.414555
CAST calpastatin 0.41221
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.409869
UBA1 ubiquitin-like modifier activating enzyme 1 0.408309
NQO1 NAD(P)H dehydrogenase, quinone 1 0.407919
USP47 ubiquitin specific peptidase 47 0.402859
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.401693
PUM1 pumilio RNA-binding family member 1 0.399751
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.395485
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.393936
UBE2A ubiquitin-conjugating enzyme E2A 0.392775
MRAP melanocortin 2 receptor accessory protein 0.392775
PTMS parathymosin 0.392001
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 0.390841
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.386979
RAD23A RAD23 homolog A (S. cerevisiae) 0.385436
CTSL cathepsin L 0.383509
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.375434
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.373899
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.372749
CASS4 Cas scaffolding protein family member 4 0.368919
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.364331
USP8 ubiquitin specific peptidase 8 0.361277
CDYL chromodomain protein, Y-like 0.360133
VCP valosin containing protein 0.356705
YBX1 Y box binding protein 1 0.345314
SNIP1 Smad nuclear interacting protein 1 0.344935
BAG6 BCL2-associated athanogene 6 0.342285
UBC ubiquitin C 0.341529
PARP1 poly (ADP-ribose) polymerase 1 0.338506
ELANE elastase, neutrophil expressed 0.335487
PPME1 protein phosphatase methylesterase 1 0.333225
CAPN3 calpain 3, (p94) 0.333225
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 0.330589
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.330589
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.319702
TPP2 tripeptidyl peptidase II 0.319328
RPS27A ribosomal protein S27a 0.318579
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.316334
IGKV1-17 immunoglobulin kappa variable 1-17 0.314465
OAZ1 ornithine decarboxylase antizyme 1 0.312597
ADRBK2 adrenergic, beta, receptor kinase 2 0.304399
DUSP12 dual specificity phosphatase 12 0.29623
UBE2I ubiquitin-conjugating enzyme E2I 0.294748
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.292527
GYLTL1B glycosyltransferase-like 1B 0.291047
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 0.290308
CRBN cereblon 0.282558
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 0.280349
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.279612
ATXN3 ataxin 3 0.279245
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.276304
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.276304
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.276304
POLH polymerase (DNA directed), eta 0.272267
ZNF197 zinc finger protein 197 0.269701
HIST1H3I histone cluster 1, H3i 0.262025
HIST1H3J histone cluster 1, H3j 0.262025
HIST1H3B histone cluster 1, H3b 0.262025
HIST1H3F histone cluster 1, H3f 0.262025
HIST1H3D histone cluster 1, H3d 0.262025
HIST1H3G histone cluster 1, H3g 0.262025
BAX BCL2-associated X protein 0.261296
MAPT microtubule-associated protein tau 0.260931
COPS5 COP9 signalosome subunit 5 0.260202
ATXN1 ataxin 1 0.259837
INS insulin 0.259109
FREM2 FRAS1 related extracellular matrix protein 2 0.259109
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.255834
CTSS cathepsin S 0.248578
DPP7 dipeptidyl-peptidase 7 0.245323
UBE2S ubiquitin-conjugating enzyme E2S 0.239197
DUSP8 dual specificity phosphatase 8 0.238837
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.235249
NQO2 NAD(P)H dehydrogenase, quinone 2 0.234891
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.233817
TAT tyrosine aminotransferase 0.232744
TPT1 tumor protein, translationally-controlled 1 0.230601
OAZ2 ornithine decarboxylase antizyme 2 0.227041
ORM1 orosomucoid 1 0.224558
FOXO1 forkhead box O1 0.22385
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.21681
ALAD aminolevulinate dehydratase 0.215761
RNF31 ring finger protein 31 0.207451
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.206423
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.205399
ZPBP zona pellucida binding protein 0.202684
EVC Ellis van Creveld protein 0.202346
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 0.200999
CANX calnexin 0.198991
HOXA2 homeobox A2 0.196999
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.192423
HIST1H3E histone cluster 1, H3e 0.190814
HIST1H3H histone cluster 1, H3h 0.189857
HIST1H3C histone cluster 1, H3c 0.189857
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.18796
CTSD cathepsin D 0.186708
PRELP proline/arginine-rich end leucine-rich repeat protein 0.185469
ACO2 aconitase 2, mitochondrial 0.182122
RAD18 RAD18 E3 ubiquitin protein ligase 0.180045
PROP1 PROP paired-like homeobox 1 0.179752
HDAC6 histone deacetylase 6 0.179752
UBE2B ubiquitin-conjugating enzyme E2B 0.178011
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.177439
SOD2 superoxide dismutase 2, mitochondrial 0.174635
EIF3F eukaryotic translation initiation factor 3, subunit F 0.174361
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.173814
UBE2T ubiquitin-conjugating enzyme E2T 0.17141
GLTSCR2 glioma tumor suppressor candidate region gene 2 0.171149
HIST1H3A histone cluster 1, H3a 0.170371
CCND1 cyclin D1 0.169604
NUB1 negative regulator of ubiquitin-like proteins 1 0.167856
DHFR dihydrofolate reductase 0.167366
PSG5 pregnancy specific beta-1-glycoprotein 5 0.165463
IGF1 insulin-like growth factor 1 (somatomedin C) 0.163641
CRYZ crystallin, zeta (quinone reductase) 0.162763
IREB2 iron-responsive element binding protein 2 0.159856
ATAD2 ATPase family, AAA domain containing 2 0.159074
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.157943
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.15776
BRDT bromodomain, testis-specific 0.157397
HIPK3 homeodomain interacting protein kinase 3 0.157039