prostatic intraepithelial neoplasia cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003692)
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Genes

9 proteins co-occuring with the tissue prostatic intraepithelial neoplasia cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
RBL2 retinoblastoma-like 2 1.4057
TOP2B topoisomerase (DNA) II beta 180kDa 1.35177
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.25369
TMPRSS2 transmembrane protease, serine 2 1.06735
GSTP1 glutathione S-transferase pi 1 0.720755
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.684735
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.636785
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.382508
AR androgen receptor 0.36302