propoxycaine-7155 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the propoxycaine-7155 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD36 ankyrin repeat domain 36
ANXA2P1 annexin A2 pseudogene 1
ARMC8 armadillo repeat containing 8
ATP9B ATPase, class II, type 9B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BSPRY B-box and SPRY domain containing
BTN2A2 butyrophilin, subfamily 2, member A2
C15ORF39 chromosome 15 open reading frame 39
C7ORF43 chromosome 7 open reading frame 43
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CASKIN2 CASK interacting protein 2
CC2D1A coiled-coil and C2 domain containing 1A
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP162 centrosomal protein 162kDa
CHD3 chromodomain helicase DNA binding protein 3
CSNK1E casein kinase 1, epsilon
CTTN cortactin
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
EHD3 EH-domain containing 3
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
ERCC1 excision repair cross-complementation group 1
FAM131B family with sequence similarity 131, member B
FAM13A family with sequence similarity 13, member A
FBXO21 F-box protein 21
FKBPL FK506 binding protein like
FOXO1 forkhead box O1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HK2 hexokinase 2
HOXB9 homeobox B9
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JMJD6 jumonji domain containing 6
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KRT34 keratin 34, type I
LMBR1L limb development membrane protein 1-like
LOXL2 lysyl oxidase-like 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAOA monoamine oxidase A
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MINK1 misshapen-like kinase 1
MRPS12 mitochondrial ribosomal protein S12
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NOTCH3 notch 3
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
ORAI3 ORAI calcium release-activated calcium modulator 3
PAPOLA poly(A) polymerase alpha
PBX2 pre-B-cell leukemia homeobox 2
PDE12 phosphodiesterase 12
PGAP3 post-GPI attachment to proteins 3
PML promyelocytic leukemia
POM121 POM121 transmembrane nucleoporin
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTN pleiotrophin
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RANBP3 RAN binding protein 3
RNFT1 ring finger protein, transmembrane 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
RTEL1 regulator of telomere elongation helicase 1
SCARB1 scavenger receptor class B, member 1
SH3BP2 SH3-domain binding protein 2
SIAH1 siah E3 ubiquitin protein ligase 1
SIK3 SIK family kinase 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SPATA5L1 spermatogenesis associated 5-like 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TAT tyrosine aminotransferase
TBC1D17 TBC1 domain family, member 17
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM212 transmembrane protein 212
TRAPPC13 trafficking protein particle complex 13
TTC12 tetratricopeptide repeat domain 12
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP18 ubiquitin specific peptidase 18
USP48 ubiquitin specific peptidase 48
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB1 zinc finger and BTB domain containing 1
ZMYM2 zinc finger, MYM-type 2
ZNF202 zinc finger protein 202
ZNF277 zinc finger protein 277
ZNF43 zinc finger protein 43
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANXA10 annexin A10
ARHGAP32 Rho GTPase activating protein 32
ARMC7 armadillo repeat containing 7
ASB7 ankyrin repeat and SOCS box containing 7
ATXN2 ataxin 2
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C9ORF40 chromosome 9 open reading frame 40
CBX8 chromobox homolog 8
CCDC130 coiled-coil domain containing 130
CDK6 cyclin-dependent kinase 6
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CSPP1 centrosome and spindle pole associated protein 1
DCLRE1A DNA cross-link repair 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLL3 delta-like 3 (Drosophila)
DOCK1 dedicator of cytokinesis 1
EYA4 EYA transcriptional coactivator and phosphatase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FGD1 FYVE, RhoGEF and PH domain containing 1
FIG4 FIG4 phosphoinositide 5-phosphatase
GID4 GID complex subunit 4
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR3 G protein-coupled receptor 3
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HSPB8 heat shock 22kDa protein 8
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IL13RA2 interleukin 13 receptor, alpha 2
IL17RA interleukin 17 receptor A
IL33 interleukin 33
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
ISL1 ISL LIM homeobox 1
ITPKB inositol-trisphosphate 3-kinase B
KIAA0232 KIAA0232
KIF22 kinesin family member 22
KIF3A kinesin family member 3A
KLK6 kallikrein-related peptidase 6
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LRRC37A3 leucine rich repeat containing 37, member A3
MCTP1 multiple C2 domains, transmembrane 1
NID2 nidogen 2 (osteonidogen)
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NXPH4 neurexophilin 4
ODF2 outer dense fiber of sperm tails 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PALMD palmdelphin
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLL polymerase (DNA directed), lambda
PRR7 proline rich 7 (synaptic)
PTK7 protein tyrosine kinase 7 (inactive)
RAB4B RAB4B, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SENP7 SUMO1/sentrin specific peptidase 7
SETD1B SET domain containing 1B
SETD6 SET domain containing 6
SIPA1 signal-induced proliferation-associated 1
SIX1 SIX homeobox 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNHG3 small nucleolar RNA host gene 3
SNIP1 Smad nuclear interacting protein 1
SOX12 SRY (sex determining region Y)-box 12
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STK16 serine/threonine kinase 16
SUGCT succinyl-CoA:glutarate-CoA transferase
TGS1 trimethylguanosine synthase 1
THBS3 thrombospondin 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM110 transmembrane protein 110
TMEM132A transmembrane protein 132A
TNNI3 troponin I type 3 (cardiac)
TNS2 tensin 2
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRIM45 tripartite motif containing 45
TSC1 tuberous sclerosis 1
TUBA3C tubulin, alpha 3c
WDR76 WD repeat domain 76
ZFP69B ZFP69 zinc finger protein B
ZNF34 zinc finger protein 34
ZNF551 zinc finger protein 551
ZNF84 zinc finger protein 84