propofol-3386 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the propofol-3386 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AKR1C1 aldo-keto reductase family 1, member C1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARC activity-regulated cytoskeleton-associated protein
ARHGAP1 Rho GTPase activating protein 1
ATF3 activating transcription factor 3
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BTN3A1 butyrophilin, subfamily 3, member A1
C19ORF57 chromosome 19 open reading frame 57
CD47 CD47 molecule
CD48 CD48 molecule
CD83 CD83 molecule
CDRT1 CMT1A duplicated region transcript 1
CFAP69 cilia and flagella associated protein 69
CNTN5 contactin 5
DDIT3 DNA-damage-inducible transcript 3
DIO2 deiodinase, iodothyronine, type II
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP1 dual specificity phosphatase 1
E2F5 E2F transcription factor 5, p130-binding
EDN1 endothelin 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR4 early growth response 4
EMP3 epithelial membrane protein 3
ERO1LB ERO1-like beta (S. cerevisiae)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP3 fatty acid binding protein 3, muscle and heart
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GEM GTP binding protein overexpressed in skeletal muscle
GM2A GM2 ganglioside activator
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTP1 glutathione S-transferase pi 1
HBEGF heparin-binding EGF-like growth factor
HIST1H2BG histone cluster 1, H2bg
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3F histone cluster 1, H3f
HIST1H4H histone cluster 1, H4h
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXB5 homeobox B5
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL1B interleukin 1, beta
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ITGA8 integrin, alpha 8
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KIAA1462 KIAA1462
KIF21B kinesin family member 21B
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK14 mitogen-activated protein kinase 14
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MPZ myelin protein zero
MX1 MX dynamin-like GTPase 1
MXD1 MAX dimerization protein 1
MYL10 myosin, light chain 10, regulatory
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PER1 period circadian clock 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA3 paraneoplastic Ma antigen 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS2 regulator of G-protein signaling 2
RUNX1 runt-related transcription factor 1
SCLY selenocysteine lyase
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC25A30 solute carrier family 25, member 30
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STS steroid sulfatase (microsomal), isozyme S
TEX14 testis expressed 14
TMEM59L transmembrane protein 59-like
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRBC1 T cell receptor beta constant 1
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP10 Rho GTPase activating protein 10
ARPIN actin-related protein 2/3 complex inhibitor
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
C19ORF66 chromosome 19 open reading frame 66
C4ORF29 chromosome 4 open reading frame 29
CA11 carbonic anhydrase XI
CAPN5 calpain 5
CDK18 cyclin-dependent kinase 18
CHKB choline kinase beta
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DTX2 deltex 2, E3 ubiquitin ligase
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FAM86C1 family with sequence similarity 86, member C1
FKBP8 FK506 binding protein 8, 38kDa
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR143 G protein-coupled receptor 143
GRAMD1C GRAM domain containing 1C
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT22 intraflagellar transport 22
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KIF13A kinesin family member 13A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LHX6 LIM homeobox 6
LINC00597 long intergenic non-protein coding RNA 597
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MRPL52 mitochondrial ribosomal protein L52
MST1R macrophage stimulating 1 receptor
MTCP1 mature T-cell proliferation 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NLRX1 NLR family member X1
NME5 NME/NM23 family member 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMP22 peripheral myelin protein 22
POLH polymerase (DNA directed), eta
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON2 spondin 2, extracellular matrix protein
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STIM1 stromal interaction molecule 1
SUN2 Sad1 and UNC84 domain containing 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBKBP1 TBK1 binding protein 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TMEM159 transmembrane protein 159
TMEM180 transmembrane protein 180
TMPRSS4 transmembrane protease, serine 4
TUBA3C tubulin, alpha 3c
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
WDR76 WD repeat domain 76
WDR78 WD repeat domain 78
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFHX2 zinc finger homeobox 2
ZFHX4 zinc finger homeobox 4
ZNF136 zinc finger protein 136
ZNF205 zinc finger protein 205
ZNF423 zinc finger protein 423
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF804A zinc finger protein 804A