propantheline bromide-4798 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the propantheline bromide-4798 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTL8 actin-like 8
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX15 arachidonate 15-lipoxygenase
ANP32A-IT1 ANP32A intronic transcript 1
APC adenomatous polyposis coli
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARPIN actin-related protein 2/3 complex inhibitor
ATM ATM serine/threonine kinase
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BGN biglycan
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF63 chromosome 11 open reading frame 63
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD14 caspase recruitment domain family, member 14
CASR calcium-sensing receptor
CBX8 chromobox homolog 8
CCR2 chemokine (C-C motif) receptor 2
CDYL chromodomain protein, Y-like
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFLAR CASP8 and FADD-like apoptosis regulator
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
COPE coatomer protein complex, subunit epsilon
CXORF21 chromosome X open reading frame 21
DBN1 drebrin 1
DLC1 DLC1 Rho GTPase activating protein
DLX2 distal-less homeobox 2
EDNRB endothelin receptor type B
EHD1 EH-domain containing 1
EPHA1 EPH receptor A1
EXOC7 exocyst complex component 7
FDPS farnesyl diphosphate synthase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLP1R glucagon-like peptide 1 receptor
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HFE hemochromatosis
HOXC5 homeobox C5
HSPA12A heat shock 70kDa protein 12A
IL11 interleukin 11
INO80B INO80 complex subunit B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LRRN3 leucine rich repeat neuronal 3
LTBP4 latent transforming growth factor beta binding protein 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MARS methionyl-tRNA synthetase
MBTD1 mbt domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MXRA5 matrix-remodelling associated 5
NAT6 N-acetyltransferase 6 (GCN5-related)
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFX1 nuclear transcription factor, X-box binding 1
NOL12 nucleolar protein 12
NPR2 natriuretic peptide receptor 2
OASL 2'-5'-oligoadenylate synthetase-like
PAX2 paired box 2
PAX5 paired box 5
PCDH1 protocadherin 1
PEAK1 pseudopodium-enriched atypical kinase 1
PIDD1 p53-induced death domain protein 1
PLLP plasmolipin
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POMT2 protein-O-mannosyltransferase 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PUM1 pumilio RNA-binding family member 1
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SOS2 son of sevenless homolog 2 (Drosophila)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TEP1 telomerase-associated protein 1
TMPRSS4 transmembrane protease, serine 4
TONSL tonsoku-like, DNA repair protein
TP53I11 tumor protein p53 inducible protein 11
TPMT thiopurine S-methyltransferase
TPR translocated promoter region, nuclear basket protein
TSC22D2 TSC22 domain family, member 2
WSCD1 WSC domain containing 1
WWOX WW domain containing oxidoreductase

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADM adrenomedullin
ALPK1 alpha-kinase 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CAMKMT calmodulin-lysine N-methyltransferase
CASD1 CAS1 domain containing 1
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPJ centromere protein J
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CPED1 cadherin-like and PC-esterase domain containing 1
CTAGE9 CTAGE family, member 9
CUZD1 CUB and zona pellucida-like domains 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM110B family with sequence similarity 110, member B
FBXO22 F-box protein 22
FGGY FGGY carbohydrate kinase domain containing
FILIP1L filamin A interacting protein 1-like
FKBP1B FK506 binding protein 1B, 12.6 kDa
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HDAC4 histone deacetylase 4
HIST1H2AI histone cluster 1, H2ai
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIZ kizuna centrosomal protein
KLF3 Kruppel-like factor 3 (basic)
LAMP3 lysosomal-associated membrane protein 3
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LTBP2 latent transforming growth factor beta binding protein 2
MAP2 microtubule-associated protein 2
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MEFV Mediterranean fever
MMP2 matrix metallopeptidase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPS18C mitochondrial ribosomal protein S18C
MUC3B mucin 3B, cell surface associated
NEUROD1 neuronal differentiation 1
NRTN neurturin
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAIP2B poly(A) binding protein interacting protein 2B
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PRR4 proline rich 4 (lacrimal)
PRSS53 protease, serine, 53
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RPL10L ribosomal protein L10-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A2 S100 calcium binding protein A2
SIGLEC15 sialic acid binding Ig-like lectin 15
SKA1 spindle and kinetochore associated complex subunit 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC41A3 solute carrier family 41, member 3
SND1-IT1 SND1 intronic transcript 1
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
STON1 stonin 1
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
SYNC syncoilin, intermediate filament protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN2 tectonic family member 2
TRIM25 tripartite motif containing 25
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSGA10 testis specific, 10
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VSIG10 V-set and immunoglobulin domain containing 10
ZNF16 zinc finger protein 16
ZNF34 zinc finger protein 34
ZNF430 zinc finger protein 430
ZNF552 zinc finger protein 552
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747