propantheline bromide-4214 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the propantheline bromide-4214 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADRA1A adrenoceptor alpha 1A
AREG amphiregulin
ARTN artemin
ATN1 atrophin 1
BTG2 BTG family, member 2
C6ORF10 chromosome 6 open reading frame 10
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAPN10 calpain 10
CASR calcium-sensing receptor
CCDC71 coiled-coil domain containing 71
CD28 CD28 molecule
CD40LG CD40 ligand
CD52 CD52 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
COL17A1 collagen, type XVII, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CTRC chymotrypsin C (caldecrin)
CXCR2 chemokine (C-X-C motif) receptor 2
DOK4 docking protein 4
DOK5 docking protein 5
DPF1 D4, zinc and double PHD fingers family 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA4 GATA binding protein 4
GFER growth factor, augmenter of liver regeneration
GFI1 growth factor independent 1 transcription repressor
GLRA2 glycine receptor, alpha 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPC3 glypican 3
GPR137 G protein-coupled receptor 137
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
IGSF6 immunoglobulin superfamily, member 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRT31 keratin 31, type I
LARGE like-glycosyltransferase
LINC00652 long intergenic non-protein coding RNA 652
LINC01587 long intergenic non-protein coding RNA 1587
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP1 low density lipoprotein receptor-related protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEP1B meprin A, beta
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
N4BP2L1 NEDD4 binding protein 2-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCALD neurocalcin delta
NF1 neurofibromin 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPR1 natriuretic peptide receptor 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRF1 nuclear respiratory factor 1
NUMA1 nuclear mitotic apparatus protein 1
PALM paralemmin
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX8 paired box 8
PDE4B phosphodiesterase 4B, cAMP-specific
PIP prolactin-induced protein
PRB4 proline-rich protein BstNI subfamily 4
PRKCA protein kinase C, alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRU protein tyrosine phosphatase, receptor type, U
RB1 retinoblastoma 1
REG1A regenerating islet-derived 1 alpha
REPS1 RALBP1 associated Eps domain containing 1
RHO rhodopsin
RPL35A ribosomal protein L35a
RTN2 reticulon 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC6A16 solute carrier family 6, member 16
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMAD1 SMAD family member 1
SMC1A structural maintenance of chromosomes 1A
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNED1 sushi, nidogen and EGF-like domains 1
SRCAP Snf2-related CREBBP activator protein
TAS2R10 taste receptor, type 2, member 10
TBC1D2B TBC1 domain family, member 2B
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TP63 tumor protein p63
TTLL4 tubulin tyrosine ligase-like family member 4
VAX2 ventral anterior homeobox 2
VWA5A von Willebrand factor A domain containing 5A
ZC3H13 zinc finger CCCH-type containing 13
ZNF407 zinc finger protein 407
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
AKR1C4 aldo-keto reductase family 1, member C4
ANXA10 annexin A10
BDKRB1 bradykinin receptor B1
BDNF brain-derived neurotrophic factor
BEND5 BEN domain containing 5
C1R complement component 1, r subcomponent
CDK3 cyclin-dependent kinase 3
CEMP1 cementum protein 1
CEP131 centrosomal protein 131kDa
CLDN1 claudin 1
CLTCL1 clathrin, heavy chain-like 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1R colony stimulating factor 1 receptor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF56 chromosome X open reading frame 56
DLK2 delta-like 2 homolog (Drosophila)
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM134B family with sequence similarity 134, member B
FAM184A family with sequence similarity 184, member A
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDAP1 ganglioside induced differentiation associated protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLDC glycine dehydrogenase (decarboxylating)
GRAMD1C GRAM domain containing 1C
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H2BN histone cluster 1, H2bn
HIST1H3F histone cluster 1, H3f
HIST2H2AA3 histone cluster 2, H2aa3
HOXA6 homeobox A6
ICOS inducible T-cell co-stimulator
IL17RB interleukin 17 receptor B
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM7A lysine (K)-specific demethylase 7A
KRT86 keratin 86, type II
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LY86 lymphocyte antigen 86
MAGEH1 melanoma antigen family H1
MAL mal, T-cell differentiation protein
MATN3 matrilin 3
MN1 meningioma (disrupted in balanced translocation) 1
MRPL41 mitochondrial ribosomal protein L41
MTCP1 mature T-cell proliferation 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPHN1 oligophrenin 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE8B phosphodiesterase 8B
PEX26 peroxisomal biogenesis factor 26
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD3 phospholipase D family, member 3
PMCH pro-melanin-concentrating hormone
PRDM14 PR domain containing 14
PROX1 prospero homeobox 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SCIN scinderin
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM132A transmembrane protein 132A
TMEM53 transmembrane protein 53
TMPRSS4 transmembrane protease, serine 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
ZBTB6 zinc finger and BTB domain containing 6
ZNF286A zinc finger protein 286A
ZNF391 zinc finger protein 391
ZNF492 zinc finger protein 492
ZNF506 zinc finger protein 506