pronetalol-2902 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the pronetalol-2902 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARHGAP26 Rho GTPase activating protein 26
ARHGAP44 Rho GTPase activating protein 44
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARR3 arrestin 3, retinal (X-arrestin)
ATF7IP activating transcription factor 7 interacting protein
BLNK B-cell linker
BTF3P11 basic transcription factor 3 pseudogene 11
CA5B carbonic anhydrase VB, mitochondrial
CA7 carbonic anhydrase VII
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CD209 CD209 molecule
CD34 CD34 molecule
CLEC4A C-type lectin domain family 4, member A
CNTN1 contactin 1
COL17A1 collagen, type XVII, alpha 1
CRELD1 cysteine-rich with EGF-like domains 1
CYB5A cytochrome b5 type A (microsomal)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EFR3B EFR3 homolog B (S. cerevisiae)
ETV1 ets variant 1
EXOSC2 exosome component 2
FCMR Fc fragment of IgM receptor
FER fer (fps/fes related) tyrosine kinase
FGFBP1 fibroblast growth factor binding protein 1
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
GAA glucosidase, alpha; acid
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GBP1 guanylate binding protein 1, interferon-inducible
GFER growth factor, augmenter of liver regeneration
GIPC1 GIPC PDZ domain containing family, member 1
GP6 glycoprotein VI (platelet)
GPR107 G protein-coupled receptor 107
HDLBP high density lipoprotein binding protein
HOXB5 homeobox B5
HOXB6 homeobox B6
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HYI hydroxypyruvate isomerase (putative)
IDUA iduronidase, alpha-L-
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0226L KIAA0226-like
KLHL3 kelch-like family member 3
LMNA lamin A/C
LRRC15 leucine rich repeat containing 15
LRRC6 leucine rich repeat containing 6
LTBP1 latent transforming growth factor beta binding protein 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MYL10 myosin, light chain 10, regulatory
MYO5C myosin VC
NEBL nebulette
NIPAL2 NIPA-like domain containing 2
NLRP1 NLR family, pyrin domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPR3 natriuretic peptide receptor 3
PAPPA2 pappalysin 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM4 PDZ and LIM domain 4
PEX10 peroxisomal biogenesis factor 10
PHF1 PHD finger protein 1
PHF7 PHD finger protein 7
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCH1 phospholipase C, eta 1
PLK3 polo-like kinase 3
POMT2 protein-O-mannosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PRX periaxin
PTCRA pre T-cell antigen receptor alpha
REC8 REC8 meiotic recombination protein
RGS10 regulator of G-protein signaling 10
RNF17 ring finger protein 17
RNF39 ring finger protein 39
SAA4 serum amyloid A4, constitutive
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SH3D21 SH3 domain containing 21
SOCS2 suppressor of cytokine signaling 2
SP140 SP140 nuclear body protein
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STOM stomatin
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TACR1 tachykinin receptor 1
TAS2R1 taste receptor, type 2, member 1
TBX6 T-box 6
TCP11L1 t-complex 11, testis-specific-like 1
TFF2 trefoil factor 2
TPMT thiopurine S-methyltransferase
TRIM29 tripartite motif containing 29
TUBA3C tubulin, alpha 3c
VASH1 vasohibin 1
VPRBP Vpr (HIV-1) binding protein
YBX3 Y box binding protein 3
ZNF177 zinc finger protein 177
ZNF276 zinc finger protein 276
ZNF492 zinc finger protein 492

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD17B abhydrolase domain containing 17B
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKTIP AKT interacting protein
ANO10 anoctamin 10
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
C10ORF2 chromosome 10 open reading frame 2
C14ORF159 chromosome 14 open reading frame 159
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
CCDC109B coiled-coil domain containing 109B
CD82 CD82 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP7 charged multivesicular body protein 7
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSF3R colony stimulating factor 3 receptor (granulocyte)
DEAF1 DEAF1 transcription factor
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMBP dynamin binding protein
DPY19L2P2 DPY19L2 pseudogene 2
E4F1 E4F transcription factor 1
ECI1 enoyl-CoA delta isomerase 1
ELAC1 elaC ribonuclease Z 1
ELP6 elongator acetyltransferase complex subunit 6
ENAH enabled homolog (Drosophila)
ERCC3 excision repair cross-complementation group 3
FAM50B family with sequence similarity 50, member B
FIP1L1 factor interacting with PAPOLA and CPSF1
FPGS folylpolyglutamate synthase
GCH1 GTP cyclohydrolase 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPHN gephyrin
GPR63 G protein-coupled receptor 63
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HOXA1 homeobox A1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IPO8 importin 8
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIF18A kinesin family member 18A
LOC157562 uncharacterized LOC157562
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK12 mitogen-activated protein kinase 12
MCRS1 microspherule protein 1
METTL21B methyltransferase like 21B
METTL8 methyltransferase like 8
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MTERF4 mitochondrial transcription termination factor 4
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUM1 melanoma associated antigen (mutated) 1
MX1 MX dynamin-like GTPase 1
NABP2 nucleic acid binding protein 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NT5M 5',3'-nucleotidase, mitochondrial
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD7 PDZ domain containing 7
PIAS3 protein inhibitor of activated STAT, 3
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLA2G15 phospholipase A2, group XV
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP6R3 protein phosphatase 6, regulatory subunit 3
PROSER1 proline and serine rich 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RFTN1 raftlin, lipid raft linker 1
RNF123 ring finger protein 123
ROGDI rogdi homolog (Drosophila)
RUVBL1 RuvB-like AAA ATPase 1
SALL2 spalt-like transcription factor 2
SCAI suppressor of cancer cell invasion
SNHG20 small nucleolar RNA host gene 20
SPAG1 sperm associated antigen 1
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TEC tec protein tyrosine kinase
THAP10 THAP domain containing 10
TMOD3 tropomodulin 3 (ubiquitous)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM16 tripartite motif containing 16
TSPYL2 TSPY-like 2
TUBA3D tubulin, alpha 3d
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR91 WD repeat domain 91
YIPF1 Yip1 domain family, member 1
ZFP30 ZFP30 zinc finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF225 zinc finger protein 225
ZNF250 zinc finger protein 250
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF480 zinc finger protein 480
ZNF529 zinc finger protein 529