promyelocytic leukemia cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A cell of a type of acute myeloid leukemia, a quickly progressing disease in which too many immature blood-forming cells are found in the blood and bone marrow. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001797)
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Genes

264 proteins co-occuring with the tissue promyelocytic leukemia cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.23628
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.11509
BPIFB2 BPI fold containing family B, member 2 1.07574
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.05369
PARP1 poly (ADP-ribose) polymerase 1 1.01943
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.00545
RARA retinoic acid receptor, alpha 0.998908
ANXA5 annexin A5 0.965928
TOP1 topoisomerase (DNA) I 0.918206
BAX BCL2-associated X protein 0.890525
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.885015
KDM3B lysine (K)-specific demethylase 3B 0.883321
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.876129
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.83448
CSF1R colony stimulating factor 1 receptor 0.818994
TFRC transferrin receptor 0.814815
THEMIS2 thymocyte selection associated family member 2 0.7711
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.735559
BRAP BRCA1 associated protein 0.722809
HINFP histone H4 transcription factor 0.717472
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.698625
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.690859
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.685551
PBK PDZ binding kinase 0.674543
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.657866
CAT catalase 0.652183
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.650154
EMC3 ER membrane protein complex subunit 3 0.64529
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.642048
STMN1 stathmin 1 0.635572
ANXA8 annexin A8 0.633549
GABARAP GABA(A) receptor-associated protein 0.62991
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.621831
BCL2L12 BCL2-like 12 (proline rich) 0.610943
CD33 CD33 molecule 0.610943
TYMS thymidylate synthetase 0.608124
LTBP4 latent transforming growth factor beta binding protein 4 0.593247
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.584422
OSTM1 osteopetrosis associated transmembrane protein 1 0.58282
FEN1 flap structure-specific endonuclease 1 0.575616
MNDA myeloid cell nuclear differentiation antigen 0.572818
EPX eosinophil peroxidase 0.555671
MPO myeloperoxidase 0.555671
CSF1 colony stimulating factor 1 (macrophage) 0.543359
ICK intestinal cell (MAK-like) kinase 0.542566
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.538604
ODC1 ornithine decarboxylase 1 0.534647
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.531484
PLSCR1 phospholipid scramblase 1 0.531089
CCND3 cyclin D3 0.530298
RARS arginyl-tRNA synthetase 0.525955
PML promyelocytic leukemia 0.523194
HRH2 histamine receptor H2 0.496874
CDK6 cyclin-dependent kinase 6 0.495701
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.493354
TOP3A topoisomerase (DNA) III alpha 0.489057
CCNC cyclin C 0.485156
FOS FBJ murine osteosarcoma viral oncogene homolog 0.484376
POLI polymerase (DNA directed) iota 0.47348
PAPD7 PAP associated domain containing 7 0.465335
JUN jun proto-oncogene 0.459145
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.456442
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.454126
CALCOCO2 calcium binding and coiled-coil domain 2 0.452198
NLE1 notchless homolog 1 (Drosophila) 0.440658
ACP5 acid phosphatase 5, tartrate resistant 0.43989
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.432608
CUL5 cullin 5 0.424581
BCL2L1 BCL2-like 1 0.420766
DUOX2 dual oxidase 2 0.419242
DUOX1 dual oxidase 1 0.417337
TNF tumor necrosis factor 0.417337
OVCA2 ovarian tumor suppressor candidate 2 0.415814
COCH cochlin 0.414293
CD1E CD1e molecule 0.41087
LTBP3 latent transforming growth factor beta binding protein 3 0.41087
SMS spermine synthase 0.410111
RBP1 retinol binding protein 1, cellular 0.399114
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.398925
LTBP2 latent transforming growth factor beta binding protein 2 0.398357
XAB2 XPA binding protein 2 0.397789
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.397222
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.396465
EXO1 exonuclease 1 0.396465
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.396465
KDM7A lysine (K)-specific demethylase 7A 0.395331
LYZ lysozyme 0.390421
SRM spermidine synthase 0.390044
FAM215A family with sequence similarity 215, member A (non-protein coding) 0.38439
HOXA4 homeobox A4 0.38439
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.383825
CDK4 cyclin-dependent kinase 4 0.380627
ING1 inhibitor of growth family, member 1 0.37687
HOXA3 homeobox A3 0.36302
LTBP1 latent transforming growth factor beta binding protein 1 0.362273
BLVRA biliverdin reductase A 0.361155
CDK2 cyclin-dependent kinase 2 0.355942
ACACB acetyl-CoA carboxylase beta 0.355942
TF transferrin 0.35334
EBNA1BP2 EBNA1 binding protein 2 0.348148
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.347408
CCND1 cyclin D1 0.346668
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.344449
SP140 SP140 nuclear body protein 0.342048
NPSR1 neuropeptide S receptor 1 0.329727
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.328628
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.327896
SYCN syncollin 0.325701
MTO1 mitochondrial tRNA translation optimization 1 0.323874
TRAF2 TNF receptor-associated factor 2 0.322779
DNASE2 deoxyribonuclease II, lysosomal 0.320227
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.319681
BCL2 B-cell CLL/lymphoma 2 0.319498
HIST1H4I histone cluster 1, H4i 0.308612
HIST1H4F histone cluster 1, H4f 0.308612
HIST1H4A histone cluster 1, H4a 0.308612
HIST2H4B histone cluster 2, H4b 0.308612
HIST1H4E histone cluster 1, H4e 0.308612
HIST1H4B histone cluster 1, H4b 0.308612
HIST1H4C histone cluster 1, H4c 0.308612
HIST1H4D histone cluster 1, H4d 0.308612
HIST1H4K histone cluster 1, H4k 0.308612
HIST1H4J histone cluster 1, H4j 0.308612
HIST1H4H histone cluster 1, H4h 0.308612
HIST2H4A histone cluster 2, H4a 0.308251
HIST1H4L histone cluster 1, H4l 0.307167
HIST4H4 histone cluster 4, H4 0.306805
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.303559
BCAR1 breast cancer anti-estrogen resistance 1 0.297806
IER2 immediate early response 2 0.295655
SP8 Sp8 transcription factor 0.292079
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.284962
ZNF24 zinc finger protein 24 0.283545
IL9 interleukin 9 0.283191
NEK1 NIMA-related kinase 1 0.28266
MTSS1 metastasis suppressor 1 0.28107
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 0.280188
CCND2 cyclin D2 0.278603
NPTN neuroplastin 0.2723
ZFY zinc finger protein, Y-linked 0.270909
CD34 CD34 molecule 0.270214
CARD17 caspase recruitment domain family, member 17 0.266413
ASB2 ankyrin repeat and SOCS box containing 2 0.265553
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.262815
PDGFB platelet-derived growth factor beta polypeptide 0.262645
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.259929
MX2 MX dynamin-like GTPase 2 0.257907
DCK deoxycytidine kinase 0.256234
RER1 retention in endoplasmic reticulum sorting receptor 1 0.2559
DPH1 diphthamide biosynthesis 1 0.255401
KLK8 kallikrein-related peptidase 8 0.255234
FPGS folylpolyglutamate synthase 0.25259
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.250627
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.247399
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.246919
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.242983
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.242672
PPP6C protein phosphatase 6, catalytic subunit 0.241132
DMPK dystrophia myotonica-protein kinase 0.24052
H3F3B H3 histone, family 3B (H3.3B) 0.239307
H3F3A H3 histone, family 3A 0.239307
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.238706
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.238406
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.238108
PPP5C protein phosphatase 5, catalytic subunit 0.237959
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.237513
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.236186
RCC1 regulator of chromosome condensation 1 0.23604
VNN2 vanin 2 0.235167
SRGN serglycin 0.23459
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.234446
LIG1 ligase I, DNA, ATP-dependent 0.234016
HSPA4 heat shock 70kDa protein 4 0.233731
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.232317
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.232039
ADAM21 ADAM metallopeptidase domain 21 0.231482
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.23011
ACACA acetyl-CoA carboxylase alpha 0.229568
SRSF2 serine/arginine-rich splicing factor 2 0.228497
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.226411
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.226283
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 0.226155
TM4SF1 transmembrane 4 L six family member 1 0.224645
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.223177
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.222342
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.221989
DAPK1 death-associated protein kinase 1 0.221061
CDC25B cell division cycle 25B 0.220831
CUL2 cullin 2 0.220378
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.219264
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.218722
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.218398
CD38 CD38 molecule 0.218398
IFNA1 interferon, alpha 1 0.217974
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.217868
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.215631
PPP4C protein phosphatase 4, catalytic subunit 0.212499
CTSA cathepsin A 0.21084
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.210447
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.206595
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.203692
TSPAN8 tetraspanin 8 0.202512
CFAP74 cilia and flagella associated protein 74 0.202185
KDM6B lysine (K)-specific demethylase 6B 0.20191
CDA cytidine deaminase 0.20191
FAS Fas cell surface death receptor 0.201585
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.200827
BORA bora, aurora kinase A activator 0.200322
PLG plasminogen 0.200251
MALL mal, T-cell differentiation protein-like 0.199939
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.199752
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.199481
TRIM24 tripartite motif containing 24 0.199248
HDAC8 histone deacetylase 8 0.198586
DHFR dihydrofolate reductase 0.198559
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.197975
CDK1 cyclin-dependent kinase 1 0.197952
LTF lactotransferrin 0.197584
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.197491
ZNF77 zinc finger protein 77 0.197012
SP100 SP100 nuclear antigen 0.196973
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.196757
CD53 CD53 molecule 0.196708
SPA17 sperm autoantigenic protein 17 0.196658
MSH3 mutS homolog 3 0.196589
PRPF4B pre-mRNA processing factor 4B 0.19648
IFNG interferon, gamma 0.19639
TLK1 tousled-like kinase 1 0.19632
FTL ferritin, light polypeptide 0.196289
HECA headcase homolog (Drosophila) 0.195865
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 0.195726
STK4 serine/threonine kinase 4 0.195704
GYPE glycophorin E (MNS blood group) 0.195574
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.195283
PRKD3 protein kinase D3 0.195168
TP53 tumor protein p53 0.19511
SELPLG selectin P ligand 0.195075
PLK4 polo-like kinase 4 0.195063
ENO2 enolase 2 (gamma, neuronal) 0.194945
IL3 interleukin 3 0.194933
NUMBL numb homolog (Drosophila)-like 0.194715
CTNNBIP1 catenin, beta interacting protein 1 0.194703
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.194679
SPN sialophorin 0.194604
CD63 CD63 molecule 0.194492
CD37 CD37 molecule 0.194479
LPO lactoperoxidase 0.194441
CHPF chondroitin polymerizing factor 0.193849
SAT1 spermidine/spermine N1-acetyltransferase 1 0.193822
SOD2 superoxide dismutase 2, mitochondrial 0.193794
KLK6 kallikrein-related peptidase 6 0.193329
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.193329
MMD monocyte to macrophage differentiation-associated 0.192591
FGF3 fibroblast growth factor 3 0.192481
ENDOG endonuclease G 0.192433
FTH1 ferritin, heavy polypeptide 1 0.192142
AHCY adenosylhomocysteinase 0.191942
KIAA0101 KIAA0101 0.191807
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.191104
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.191031
CD7 CD7 molecule 0.191013
MARK2 MAP/microtubule affinity-regulating kinase 2 0.191013
UBASH3B ubiquitin associated and SH3 domain containing B 0.190865
SRI sorcin 0.189931