promazine-6028 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the promazine-6028 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACRV1 acrosomal vesicle protein 1
ADAM22 ADAM metallopeptidase domain 22
ADRA1A adrenoceptor alpha 1A
ANAPC13 anaphase promoting complex subunit 13
ARTN artemin
ATF7 activating transcription factor 7
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN2L ataxin 2-like
BCL6 B-cell CLL/lymphoma 6
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP8A bone morphogenetic protein 8a
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF105 chromosome 14 open reading frame 105
C19ORF26 chromosome 19 open reading frame 26
CAMKV CaM kinase-like vesicle-associated
CNOT2 CCR4-NOT transcription complex, subunit 2
COL4A2 collagen, type IV, alpha 2
CRHR2 corticotropin releasing hormone receptor 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DFNA5 deafness, autosomal dominant 5
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELMO1 engulfment and cell motility 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ETV5 ets variant 5
EXOSC2 exosome component 2
FAM63B family with sequence similarity 63, member B
FAXDC2 fatty acid hydroxylase domain containing 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GALR2 galanin receptor 2
GFER growth factor, augmenter of liver regeneration
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC2P3 hect domain and RLD 2 pseudogene 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA10 homeobox A10
HOXA9 homeobox A9
HYAL1 hyaluronoglucosaminidase 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL16 interleukin 16
INSIG1 insulin induced gene 1
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KLK13 kallikrein-related peptidase 13
LENEP lens epithelial protein
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MEF2D myocyte enhancer factor 2D
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MRPL41 mitochondrial ribosomal protein L41
MVD mevalonate (diphospho) decarboxylase
MYO9B myosin IXB
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NHLH2 nescient helix loop helix 2
NINJ2 ninjurin 2
NME5 NME/NM23 family member 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NSUN6 NOP2/Sun domain family, member 6
NTN1 netrin 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PML promyelocytic leukemia
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRM protein tyrosine phosphatase, receptor type, M
PVR poliovirus receptor
PYY peptide YY
RB1 retinoblastoma 1
RGS10 regulator of G-protein signaling 10
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SAP30 Sin3A-associated protein, 30kDa
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELL selectin L
SH2D3A SH2 domain containing 3A
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A3 solute carrier family 43, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNED1 sushi, nidogen and EGF-like domains 1
SNX29P2 sorting nexin 29 pseudogene 2
SPRY4 sprouty homolog 4 (Drosophila)
STATH statherin
STC1 stanniocalcin 1
STMN3 stathmin-like 3
TCF3 transcription factor 3
TJAP1 tight junction associated protein 1 (peripheral)
TRIM36 tripartite motif containing 36
TYMP thymidine phosphorylase
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
AFAP1 actin filament associated protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATG10 autophagy related 10
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CD83 CD83 molecule
CD8A CD8a molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CLDN17 claudin 17
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CPB1 carboxypeptidase B1 (tissue)
CRMP1 collapsin response mediator protein 1
CTSF cathepsin F
DCAF4 DDB1 and CUL4 associated factor 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAL4 dynein, axonemal, light chain 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EVPL envoplakin
FAM76A family with sequence similarity 76, member A
FOXI1 forkhead box I1
GPATCH2L G patch domain containing 2-like
GPATCH3 G patch domain containing 3
GPR157 G protein-coupled receptor 157
HOXA4 homeobox A4
HOXC5 homeobox C5
IL22 interleukin 22
JMJD4 jumonji domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0319L KIAA0319-like
LOC100287590 uncharacterized LOC100287590
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MSI1 musashi RNA-binding protein 1
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEC plectin
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PQLC2 PQ loop repeat containing 2
PRODH proline dehydrogenase (oxidase) 1
PRR15L proline rich 15-like
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCGB2A2 secretoglobin, family 2A, member 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SP140L SP140 nuclear body protein-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
STRA6 stimulated by retinoic acid 6
TARP TCR gamma alternate reading frame protein
TCTN2 tectonic family member 2
TRAF5 TNF receptor-associated factor 5
TRIM21 tripartite motif containing 21
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WWC2 WW and C2 domain containing 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF136 zinc finger protein 136
ZNF282 zinc finger protein 282
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF573 zinc finger protein 573
ZNF696 zinc finger protein 696