promazine-3833 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the promazine-3833 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
ADCY2 adenylate cyclase 2 (brain)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANAPC13 anaphase promoting complex subunit 13
ARC activity-regulated cytoskeleton-associated protein
ASPH aspartate beta-hydroxylase
ATF7 activating transcription factor 7
BARX2 BARX homeobox 2
BICD1 bicaudal D homolog 1 (Drosophila)
BMP5 bone morphogenetic protein 5
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CEND1 cell cycle exit and neuronal differentiation 1
CFHR4 complement factor H-related 4
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CNTD2 cyclin N-terminal domain containing 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRH corticotropin releasing hormone
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
CUZD1 CUB and zona pellucida-like domains 1
CYLD cylindromatosis (turban tumor syndrome)
CYTH4 cytohesin 4
DGKQ diacylglycerol kinase, theta 110kDa
DMRT1 doublesex and mab-3 related transcription factor 1
EGR1 early growth response 1
EPHB2 EPH receptor B2
EPS8L3 EPS8-like 3
ERCC2 excision repair cross-complementation group 2
EZR ezrin
FGF13 fibroblast growth factor 13
GAST gastrin
GK2 glycerol kinase 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H1D histone cluster 1, H1d
HOXB5 homeobox B5
HOXC4 homeobox C4
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
JAK2 Janus kinase 2
KCNIP1 Kv channel interacting protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LRRC15 leucine rich repeat containing 15
MAP2K7 mitogen-activated protein kinase kinase 7
MCAM melanoma cell adhesion molecule
MCF2L MCF.2 cell line derived transforming sequence-like
MMP13 matrix metallopeptidase 13
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAIP2B poly(A) binding protein interacting protein 2B
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PLA2G1B phospholipase A2, group IB (pancreas)
PSCA prostate stem cell antigen
PTHLH parathyroid hormone-like hormone
RBM34 RNA binding motif protein 34
RGS20 regulator of G-protein signaling 20
RPL7 ribosomal protein L7
SCRN3 secernin 3
SDS serine dehydratase
SELL selectin L
SETD1B SET domain containing 1B
SH3D21 SH3 domain containing 21
SLC16A4 solute carrier family 16, member 4
SLC22A17 solute carrier family 22, member 17
SLC45A2 solute carrier family 45, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMYD2 SET and MYND domain containing 2
SP1 Sp1 transcription factor
SPRR2B small proline-rich protein 2B
SRCAP Snf2-related CREBBP activator protein
T T, brachyury homolog (mouse)
TBKBP1 TBK1 binding protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR5 toll-like receptor 5
TMCC2 transmembrane and coiled-coil domain family 2
TMLHE trimethyllysine hydroxylase, epsilon
TMOD2 tropomodulin 2 (neuronal)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZC3H13 zinc finger CCCH-type containing 13
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANP32A-IT1 ANP32A intronic transcript 1
ATG2A autophagy related 2A
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
C11ORF80 chromosome 11 open reading frame 80
C8ORF44 chromosome 8 open reading frame 44
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCDC132 coiled-coil domain containing 132
CCNL2 cyclin L2
CD80 CD80 molecule
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHM choroideremia (Rab escort protein 1)
CIDEB cell death-inducing DFFA-like effector b
CORT cortistatin
CXADR coxsackie virus and adenovirus receptor
DAPK3 death-associated protein kinase 3
DNAH17 dynein, axonemal, heavy chain 17
DPY19L1P1 DPY19L1 pseudogene 1
DUSP13 dual specificity phosphatase 13
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
EMID1 EMI domain containing 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FKBP10 FK506 binding protein 10, 65 kDa
FUZ fuzzy planar cell polarity protein
FXYD5 FXYD domain containing ion transport regulator 5
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HDAC4 histone deacetylase 4
HIST1H3E histone cluster 1, H3e
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL22 interleukin 22
ITPKB inositol-trisphosphate 3-kinase B
KLHL28 kelch-like family member 28
KLK5 kallikrein-related peptidase 5
LIME1 Lck interacting transmembrane adaptor 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
METTL16 methyltransferase like 16
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
OSGIN1 oxidative stress induced growth inhibitor 1
PLCD1 phospholipase C, delta 1
PLEC plectin
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMEL premelanosome protein
RAB3A RAB3A, member RAS oncogene family
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPON2 spondin 2, extracellular matrix protein
SPRY2 sprouty homolog 2 (Drosophila)
STRN striatin, calmodulin binding protein
SYTL2 synaptotagmin-like 2
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TMPRSS2 transmembrane protease, serine 2
TONSL tonsoku-like, DNA repair protein
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TUBA4B tubulin, alpha 4b
TYRP1 tyrosinase-related protein 1
UBXN6 UBX domain protein 6
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WDR4 WD repeat domain 4
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF10 zinc finger protein 10
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF665 zinc finger protein 665
ZNF76 zinc finger protein 76