progesterone-3287 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the progesterone-3287 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHNAK2 AHNAK nucleoprotein 2
AIM1L absent in melanoma 1-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
APOE apolipoprotein E
ARNT aryl hydrocarbon receptor nuclear translocator
B3GAT3 beta-1,3-glucuronyltransferase 3
BDKRB2 bradykinin receptor B2
BMP1 bone morphogenetic protein 1
CARTPT CART prepropeptide
CAV2 caveolin 2
CCDC69 coiled-coil domain containing 69
CCL21 chemokine (C-C motif) ligand 21
CD58 CD58 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CPA2 carboxypeptidase A2 (pancreatic)
CPB1 carboxypeptidase B1 (tissue)
CSF1R colony stimulating factor 1 receptor
CTIF CBP80/20-dependent translation initiation factor
DNAI2 dynein, axonemal, intermediate chain 2
DSC2 desmocollin 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXTL3 exostosin-like glycosyltransferase 3
FAM63B family with sequence similarity 63, member B
FGA fibrinogen alpha chain
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXN3 forkhead box N3
FSCN1 fascin actin-bundling protein 1
GFI1 growth factor independent 1 transcription repressor
GLP1R glucagon-like peptide 1 receptor
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H3E histone cluster 1, H3e
HOXC4 homeobox C4
HYAL1 hyaluronoglucosaminidase 1
IGL immunoglobulin lambda locus
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KIF13A kinesin family member 13A
KRT17 keratin 17, type I
LAMC2 laminin, gamma 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
MFSD7 major facilitator superfamily domain containing 7
MINK1 misshapen-like kinase 1
MLXIP MLX interacting protein
MOB3B MOB kinase activator 3B
MX1 MX dynamin-like GTPase 1
N4BP3 NEDD4 binding protein 3
NCOR2 nuclear receptor corepressor 2
NEK9 NIMA-related kinase 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
PADI1 peptidyl arginine deiminase, type I
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARG poly (ADP-ribose) glycohydrolase
PCNXL2 pecanex-like 2 (Drosophila)
PER1 period circadian clock 1
PLCL2 phospholipase C-like 2
PRKCE protein kinase C, epsilon
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGDR2 prostaglandin D2 receptor 2
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM5 RNA binding motif protein 5
RGS14 regulator of G-protein signaling 14
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RND2 Rho family GTPase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SH2D3A SH2 domain containing 3A
SIPA1 signal-induced proliferation-associated 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SPRR1B small proline-rich protein 1B
STON1 stonin 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
TBX5 T-box 5
TCF20 transcription factor 20 (AR1)
TGM2 transglutaminase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAK1 trafficking protein, kinesin binding 1
TRIM2 tripartite motif containing 2
TTC9 tetratricopeptide repeat domain 9
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDTC1 WD and tetratricopeptide repeats 1
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
AFAP1 actin filament associated protein 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
C7ORF43 chromosome 7 open reading frame 43
C8ORF44 chromosome 8 open reading frame 44
CBX8 chromobox homolog 8
CCDC25 coiled-coil domain containing 25
CCDC47 coiled-coil domain containing 47
CCDC85C coiled-coil domain containing 85C
CLGN calmegin
CORT cortistatin
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DOC2A double C2-like domains, alpha
EFCAB2 EF-hand calcium binding domain 2
EGFL7 EGF-like-domain, multiple 7
EIF5A eukaryotic translation initiation factor 5A
ERN2 endoplasmic reticulum to nucleus signaling 2
FA2H fatty acid 2-hydroxylase
FAIM Fas apoptotic inhibitory molecule
FBXL7 F-box and leucine-rich repeat protein 7
FLCN folliculin
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR143 G protein-coupled receptor 143
HIST1H2AI histone cluster 1, H2ai
HIST1H2BC histone cluster 1, H2bc
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KITLG KIT ligand
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
MAGOHB mago-nashi homolog B (Drosophila)
MBNL3 muscleblind-like splicing regulator 3
MED18 mediator complex subunit 18
MMP2 matrix metallopeptidase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL44 mitochondrial ribosomal protein L44
MVP major vault protein
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPY5R neuropeptide Y receptor Y5
OGFRL1 opioid growth factor receptor-like 1
OSGIN1 oxidative stress induced growth inhibitor 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6B par-6 family cell polarity regulator beta
PDGFA platelet-derived growth factor alpha polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PGBD5 piggyBac transposable element derived 5
PIBF1 progesterone immunomodulatory binding factor 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PROS1 protein S (alpha)
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3A RAB3A, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF39 ring finger protein 39
RPS14P3 ribosomal protein S14 pseudogene 3
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SECTM1 secreted and transmembrane 1
SIX1 SIX homeobox 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SP1 Sp1 transcription factor
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBC1D19 TBC1 domain family, member 19
TMEM184C transmembrane protein 184C
TMEM209 transmembrane protein 209
UBQLN4 ubiquilin 4
WLS wntless Wnt ligand secretion mediator
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF721 zinc finger protein 721
ZNF747 zinc finger protein 747