procyclidine-4817 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the procyclidine-4817 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM11 ADAM metallopeptidase domain 11
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAM basal cell adhesion molecule (Lutheran blood group)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C21ORF2 chromosome 21 open reading frame 2
CALML5 calmodulin-like 5
CCNO cyclin O
CDK18 cyclin-dependent kinase 18
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLDN11 claudin 11
CLSTN2 calsyntenin 2
CLTC clathrin, heavy chain (Hc)
CNTNAP1 contactin associated protein 1
COMMD4 COMM domain containing 4
CRY2 cryptochrome circadian clock 2
CYHR1 cysteine/histidine-rich 1
DCAF4 DDB1 and CUL4 associated factor 4
DNAL4 dynein, axonemal, light chain 4
EFNA3 ephrin-A3
ERN1 endoplasmic reticulum to nucleus signaling 1
EVPL envoplakin
FCMR Fc fragment of IgM receptor
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GJA4 gap junction protein, alpha 4, 37kDa
GOSR2 golgi SNAP receptor complex member 2
GPATCH2L G patch domain containing 2-like
GREB1 growth regulation by estrogen in breast cancer 1
GRM1 glutamate receptor, metabotropic 1
GYPB glycophorin B (MNS blood group)
ICMT isoprenylcysteine carboxyl methyltransferase
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RA interleukin 17 receptor A
IRF9 interferon regulatory factor 9
KRIT1 KRIT1, ankyrin repeat containing
KRT8P12 keratin 8 pseudogene 12
LAMB2 laminin, beta 2 (laminin S)
LAMP3 lysosomal-associated membrane protein 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MED18 mediator complex subunit 18
MFSD11 major facilitator superfamily domain containing 11
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MR1 major histocompatibility complex, class I-related
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAT6 N-acetyltransferase 6 (GCN5-related)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLE1 notchless homolog 1 (Drosophila)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBPL10 oxysterol binding protein-like 10
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHC3 polyhomeotic homolog 3 (Drosophila)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK3 polo-like kinase 3
PLLP plasmolipin
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PRDX2 peroxiredoxin 2
QKI QKI, KH domain containing, RNA binding
RABGAP1 RAB GTPase activating protein 1
RARA retinoic acid receptor, alpha
RECQL5 RecQ protein-like 5
RHBDD3 rhomboid domain containing 3
RHOBTB2 Rho-related BTB domain containing 2
RNF31 ring finger protein 31
SMAD3 SMAD family member 3
SOCS7 suppressor of cytokine signaling 7
SOGA1 suppressor of glucose, autophagy associated 1
SPEG SPEG complex locus
STIM1 stromal interaction molecule 1
SUGP1 SURP and G patch domain containing 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TM2D1 TM2 domain containing 1
TM4SF5 transmembrane 4 L six family member 5
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53I11 tumor protein p53 inducible protein 11
TRIM29 tripartite motif containing 29
UBOX5 U-box domain containing 5
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFP64 ZFP64 zinc finger protein
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ATAT1 alpha tubulin acetyltransferase 1
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF159 chromosome 1 open reading frame 159
C21ORF91 chromosome 21 open reading frame 91
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CASP8AP2 caspase 8 associated protein 2
CD82 CD82 molecule
CDKN2AIP CDKN2A interacting protein
CLDND1 claudin domain containing 1
CRYZ crystallin, zeta (quinone reductase)
CTSV cathepsin V
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DSG2 desmoglein 2
EML4 echinoderm microtubule associated protein like 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FANCE Fanconi anemia, complementation group E
FBXL2 F-box and leucine-rich repeat protein 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ21369 uncharacterized protein FLJ21369
FRK fyn-related Src family tyrosine kinase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBAS glioblastoma amplified sequence
GCA grancalcin, EF-hand calcium binding protein
GJA1 gap junction protein, alpha 1, 43kDa
GMCL1 germ cell-less, spermatogenesis associated 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIRA histone cell cycle regulator
HIST1H2BI histone cluster 1, H2bi
HSPA2 heat shock 70kDa protein 2
ICK intestinal cell (MAK-like) kinase
INSIG2 insulin induced gene 2
KDM5C lysine (K)-specific demethylase 5C
LTBP2 latent transforming growth factor beta binding protein 2
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MEX3C mex-3 RNA binding family member C
MIR22HG MIR22 host gene
MMD monocyte to macrophage differentiation-associated
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL41 mitochondrial ribosomal protein L41
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NIPAL2 NIPA-like domain containing 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARPBP PARP1 binding protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB27B RAB27B, member RAS oncogene family
RGS17 regulator of G-protein signaling 17
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RNF2 ring finger protein 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROM1 retinal outer segment membrane protein 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RUNDC3B RUN domain containing 3B
SACS sacsin molecular chaperone
SEC24B SEC24 family member B
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F5 solute carrier family 35, member F5
SLC44A1 solute carrier family 44 (choline transporter), member 1
TBC1D19 TBC1 domain family, member 19
TFF2 trefoil factor 2
TICAM1 toll-like receptor adaptor molecule 1
TMEM183A transmembrane protein 183A
TMEM230 transmembrane protein 230
TRAPPC11 trafficking protein particle complex 11
TTLL1 tubulin tyrosine ligase-like family member 1
UEVLD UEV and lactate/malate dehyrogenase domains
UPK2 uroplakin 2
VASH2 vasohibin 2
WRN Werner syndrome, RecQ helicase-like
ZNF107 zinc finger protein 107
ZNF180 zinc finger protein 180
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF43 zinc finger protein 43
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF770 zinc finger protein 770