procyclidine-4233 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the procyclidine-4233 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH6 alcohol dehydrogenase 6 (class V)
AIRE autoimmune regulator
ALOXE3 arachidonate lipoxygenase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOH apolipoprotein H (beta-2-glycoprotein I)
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARID5A AT rich interactive domain 5A (MRF1-like)
AUTS2 autism susceptibility candidate 2
BGN biglycan
BTG2 BTG family, member 2
C22ORF24 chromosome 22 open reading frame 24
C8ORF4 chromosome 8 open reading frame 4
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD79B CD79b molecule, immunoglobulin-associated beta
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CLTC clathrin, heavy chain (Hc)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL14A1 collagen, type XIV, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CPN2 carboxypeptidase N, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDIT4 DNA-damage-inducible transcript 4
DDN dendrin
DLG4 discs, large homolog 4 (Drosophila)
DPF3 D4, zinc and double PHD fingers, family 3
EDN3 endothelin 3
EDNRA endothelin receptor type A
EDRF1 erythroid differentiation regulatory factor 1
EFS embryonal Fyn-associated substrate
EREG epiregulin
FABP3 fatty acid binding protein 3, muscle and heart
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GPR63 G protein-coupled receptor 63
GUCA1B guanylate cyclase activator 1B (retina)
HBS1L HBS1-like translational GTPase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMHB1 histocompatibility (minor) HB-1
HOXA7 homeobox A7
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP7 insulin-like growth factor binding protein 7
IHH indian hedgehog
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KIAA0485 uncharacterized LOC57235
KIF25-AS1 KIF25 antisense RNA 1
KLK13 kallikrein-related peptidase 13
LRRC2 leucine rich repeat containing 2
LRRC75B leucine rich repeat containing 75B
LY9 lymphocyte antigen 9
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MCF2L MCF.2 cell line derived transforming sequence-like
MRC2 mannose receptor, C type 2
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYF5 myogenic factor 5
MYOZ1 myozenin 1
NCR2 natural cytotoxicity triggering receptor 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPR1 natriuretic peptide receptor 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PBOV1 prostate and breast cancer overexpressed 1
PML promyelocytic leukemia
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PODXL2 podocalyxin-like 2
PRAF2 PRA1 domain family, member 2
PRDM14 PR domain containing 14
PRDM9 PR domain containing 9
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRR protein tyrosine phosphatase, receptor type, R
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STATH statherin
STK3 serine/threonine kinase 3
SYK spleen tyrosine kinase
THEMIS2 thymocyte selection associated family member 2
THPO thrombopoietin
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNS4 tensin 4
TRD T cell receptor delta locus
UBA7 ubiquitin-like modifier activating enzyme 7
VNN2 vanin 2
VPS9D1 VPS9 domain containing 1
WNT5B wingless-type MMTV integration site family, member 5B
ZMAT4 zinc finger, matrin-type 4
ZNF407 zinc finger protein 407
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AIM2 absent in melanoma 2
AK5 adenylate kinase 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA10 annexin A10
ARRB2 arrestin, beta 2
BEX4 brain expressed, X-linked 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
C1ORF35 chromosome 1 open reading frame 35
C22ORF46 chromosome 22 open reading frame 46
C2ORF44 chromosome 2 open reading frame 44
CARD8 caspase recruitment domain family, member 8
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CES3 carboxylesterase 3
CHRM3 cholinergic receptor, muscarinic 3
CINP cyclin-dependent kinase 2 interacting protein
CLDN1 claudin 1
CNN1 calponin 1, basic, smooth muscle
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DLK2 delta-like 2 homolog (Drosophila)
DOK5 docking protein 5
DUSP8 dual specificity phosphatase 8
ERCC4 excision repair cross-complementation group 4
ERO1LB ERO1-like beta (S. cerevisiae)
FBRS fibrosin
FGF20 fibroblast growth factor 20
FUZ fuzzy planar cell polarity protein
GALK1 galactokinase 1
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2L G patch domain containing 2-like
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HESX1 HESX homeobox 1
HIST1H1E histone cluster 1, H1e
HOXB9 homeobox B9
IDI2-AS1 IDI2 antisense RNA 1
IL12A interleukin 12A
IL36RN interleukin 36 receptor antagonist
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1549L KIAA1549-like
KIF13A kinesin family member 13A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LMCD1 LIM and cysteine-rich domains 1
LOC257152 uncharacterized LOC257152
LOC730101 uncharacterized LOC730101
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MED31 mediator complex subunit 31
MX1 MX dynamin-like GTPase 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PALM paralemmin
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHGB5 protocadherin gamma subfamily B, 5
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP prolactin-induced protein
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPL periplakin
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QPCTL glutaminyl-peptide cyclotransferase-like
RGS17 regulator of G-protein signaling 17
RNF122 ring finger protein 122
RPH3AL rabphilin 3A-like (without C2 domains)
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRN striatin, calmodulin binding protein
SUGCT succinyl-CoA:glutarate-CoA transferase
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THRAP3 thyroid hormone receptor associated protein 3
TMEM8B transmembrane protein 8B
TRAC T cell receptor alpha constant
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
WNT1 wingless-type MMTV integration site family, member 1
YY2 YY2 transcription factor
ZNF41 zinc finger protein 41
ZNF528 zinc finger protein 528
ZNF711 zinc finger protein 711
ZNF93 zinc finger protein 93