prochlorperazine-6664 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the prochlorperazine-6664 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM22 ADAM metallopeptidase domain 22
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADORA3 adenosine A3 receptor
ANGEL2 angel homolog 2 (Drosophila)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARMC4 armadillo repeat containing 4
AURKC aurora kinase C
BMPR1B bone morphogenetic protein receptor, type IB
BTBD18 BTB (POZ) domain containing 18
C8A complement component 8, alpha polypeptide
CARD8 caspase recruitment domain family, member 8
CD200 CD200 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFHR2 complement factor H-related 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNPY4 canopy FGF signaling regulator 4
COL14A1 collagen, type XIV, alpha 1
CORO7 coronin 7
CRISP2 cysteine-rich secretory protein 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DKFZP434C153 DKFZP434C153 protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DRD2 dopamine receptor D2
DST dystonin
ELSPBP1 epididymal sperm binding protein 1
EPHB2 EPH receptor B2
ERGIC3 ERGIC and golgi 3
FAM76A family with sequence similarity 76, member A
FSCN3 fascin actin-bundling protein 3, testicular
HCFC1 host cell factor C1
HEMK1 HemK methyltransferase family member 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IL5RA interleukin 5 receptor, alpha
JAG1 jagged 1
KIAA0485 uncharacterized LOC57235
KIF5C kinesin family member 5C
KLHL22 kelch-like family member 22
KLK13 kallikrein-related peptidase 13
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LINC00597 long intergenic non-protein coding RNA 597
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC48 leucine rich repeat containing 48
MAP2K7 mitogen-activated protein kinase kinase 7
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NMUR1 neuromedin U receptor 1
NRG1 neuregulin 1
OMD osteomodulin
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDGFB platelet-derived growth factor beta polypeptide
PGAP3 post-GPI attachment to proteins 3
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLCL2 phospholipase C-like 2
POFUT1 protein O-fucosyltransferase 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM2 PR domain containing 2, with ZNF domain
PRKG2 protein kinase, cGMP-dependent, type II
PRM2 protamine 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
R3HDM1 R3H domain containing 1
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RETN resistin
RGS14 regulator of G-protein signaling 14
RHO rhodopsin
RPL10L ribosomal protein L10-like
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SHOX2 short stature homeobox 2
SIRT4 sirtuin 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TADA3 transcriptional adaptor 3
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBR1 T-box, brain, 1
TNPO2 transportin 2
TPM1 tropomyosin 1 (alpha)
TRD T cell receptor delta locus
TRIM62 tripartite motif containing 62
TUBA3C tubulin, alpha 3c
VPRBP Vpr (HIV-1) binding protein
YBX2 Y box binding protein 2
ZNF287 zinc finger protein 287
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AFF4 AF4/FMR2 family, member 4
ANXA2P1 annexin A2 pseudogene 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
BTC betacellulin
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF29 chromosome 22 open reading frame 29
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC6 cell division cycle 6
CDKL3 cyclin-dependent kinase-like 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRYGC crystallin, gamma C
DENND5B DENN/MADD domain containing 5B
DLK2 delta-like 2 homolog (Drosophila)
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM118A family with sequence similarity 118, member A
FAM57A family with sequence similarity 57, member A
FBXO2 F-box protein 2
FRS3 fibroblast growth factor receptor substrate 3
GALNS galactosamine (N-acetyl)-6-sulfatase
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GMPR guanosine monophosphate reductase
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HSF2BP heat shock transcription factor 2 binding protein
IPO8 importin 8
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIRREL kin of IRRE like (Drosophila)
KRT20 keratin 20, type I
LMNB1 lamin B1
LPAR4 lysophosphatidic acid receptor 4
LRRC6 leucine rich repeat containing 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK12 mitogen-activated protein kinase 12
METTL16 methyltransferase like 16
MKS1 Meckel syndrome, type 1
MOCS3 molybdenum cofactor synthesis 3
NDP Norrie disease (pseudoglioma)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PHC1 polyhomeotic homolog 1 (Drosophila)
PID1 phosphotyrosine interaction domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS53 protease, serine, 53
PTPRE protein tyrosine phosphatase, receptor type, E
RAB33B RAB33B, member RAS oncogene family
RPH3A rabphilin 3A
SCML2 sex comb on midleg-like 2 (Drosophila)
SETBP1 SET binding protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC35F6 solute carrier family 35, member F6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN2 tectonic family member 2
TENM1 teneurin transmembrane protein 1
TEX40 testis expressed 40
TGFBI transforming growth factor, beta-induced, 68kDa
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA4B tubulin, alpha 4b
TUBB2B tubulin, beta 2B class IIb
TXLNG taxilin gamma
VGF VGF nerve growth factor inducible
WDR4 WD repeat domain 4
WFDC2 WAP four-disulfide core domain 2
ZNF286A zinc finger protein 286A
ZNF606 zinc finger protein 606
ZNF671 zinc finger protein 671