procainamide-2618 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the procainamide-2618 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRB2 adhesion G protein-coupled receptor B2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
ANKLE2 ankyrin repeat and LEM domain containing 2
AR androgen receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BAAT bile acid CoA:amino acid N-acyltransferase
BMP1 bone morphogenetic protein 1
BPIFA1 BPI fold containing family A, member 1
BTG2 BTG family, member 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA9 carbonic anhydrase IX
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CCDC57 coiled-coil domain containing 57
CCDC87 coiled-coil domain containing 87
CERS4 ceramide synthase 4
CHD5 chromodomain helicase DNA binding protein 5
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLPS colipase, pancreatic
COL19A1 collagen, type XIX, alpha 1
DAPK2 death-associated protein kinase 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
FBLN1 fibulin 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FKBP8 FK506 binding protein 8, 38kDa
FOXN2 forkhead box N2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GGTLC2 gamma-glutamyltransferase light chain 2
HABP4 hyaluronan binding protein 4
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H3E histone cluster 1, H3e
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXC5 homeobox C5
HR hair growth associated
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
INS insulin
INSR insulin receptor
KIAA1109 KIAA1109
KIF25-AS1 KIF25 antisense RNA 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MED31 mediator complex subunit 31
MTERF4 mitochondrial transcription termination factor 4
MYH4 myosin, heavy chain 4, skeletal muscle
MYL10 myosin, light chain 10, regulatory
MYOF myoferlin
MYRIP myosin VIIA and Rab interacting protein
NCF2 neutrophil cytosolic factor 2
NCOA2 nuclear receptor coactivator 2
NEUROG2 neurogenin 2
NF1 neurofibromin 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAPPA2 pappalysin 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PEX5 peroxisomal biogenesis factor 5
PLAC4 placenta-specific 4
PLCL2 phospholipase C-like 2
POMT2 protein-O-mannosyltransferase 2
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PRKG1 protein kinase, cGMP-dependent, type I
PVR poliovirus receptor
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAMD9 sterile alpha motif domain containing 9
SCARF1 scavenger receptor class F, member 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC22A17 solute carrier family 22, member 17
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLURP1 secreted LY6/PLAUR domain containing 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAS2R4 taste receptor, type 2, member 4
TIGD6 tigger transposable element derived 6
TMEM47 transmembrane protein 47
TNC tenascin C
TUBB7P tubulin, beta 7, pseudogene
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VASH2 vasohibin 2
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
WNT16 wingless-type MMTV integration site family, member 16

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA1 annexin A1
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP5 Rho GTPase activating protein 5
ARRB1 arrestin, beta 1
ASB9 ankyrin repeat and SOCS box containing 9
ATAD3A ATPase family, AAA domain containing 3A
ATP11B ATPase, class VI, type 11B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
C19ORF40 chromosome 19 open reading frame 40
CBR1 carbonyl reductase 1
CCDC25 coiled-coil domain containing 25
CLDN15 claudin 15
COL9A2 collagen, type IX, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CUL9 cullin 9
DCAF16 DDB1 and CUL4 associated factor 16
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FBXO31 F-box protein 31
FKBP5 FK506 binding protein 5
GATA6 GATA binding protein 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIRA histone cell cycle regulator
HOXC10 homeobox C10
IGFBP6 insulin-like growth factor binding protein 6
IGFLR1 IGF-like family receptor 1
IL15RA interleukin 15 receptor, alpha
KIAA0355 KIAA0355
KLHL26 kelch-like family member 26
LAMB2 laminin, beta 2 (laminin S)
LIN7A lin-7 homolog A (C. elegans)
LINS lines homolog (Drosophila)
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTFL1 leucine zipper transcription factor-like 1
MANEA mannosidase, endo-alpha
MAP9 microtubule-associated protein 9
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
MFSD11 major facilitator superfamily domain containing 11
MUM1 melanoma associated antigen (mutated) 1
NABP2 nucleic acid binding protein 2
NDE1 nudE neurodevelopment protein 1
NEK4 NIMA-related kinase 4
NHLRC2 NHL repeat containing 2
NOTCH1 notch 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDIA3 protein disulfide isomerase family A, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLEK2 pleckstrin 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC46A3 solute carrier family 46, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STBD1 starch binding domain 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
TXLNG taxilin gamma
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF219 zinc finger protein 219
ZNF226 zinc finger protein 226
ZNF510 zinc finger protein 510
ZNF586 zinc finger protein 586
ZNF74 zinc finger protein 74