primary thrombocytopenia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

143 genes co-occuring with the disease primary thrombocytopenia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
THPO thrombopoietin 2.07077
MPL MPL proto-oncogene, thrombopoietin receptor 1.6986
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.6791
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.47594
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 1.46144
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.28435
CD4 CD4 molecule 1.12783
CD79A CD79a molecule, immunoglobulin-associated alpha 1.12277
POU2F3 POU class 2 homeobox 3 1.06816
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.954525
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.947852
FOXG1 forkhead box G1 0.931656
VWF von Willebrand factor 0.925865
NAAA N-acylethanolamine acid amidase 0.912668
F8 coagulation factor VIII, procoagulant component 0.901156
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.894179
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.854449
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 0.848307
CD40LG CD40 ligand 0.844211
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.842573
HPSE2 heparanase 2 (inactive) 0.820437
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.804846
RHOD ras homolog family member D 0.802385
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.795002
RHD Rh blood group, D antigen 0.790902
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.789262
GATA3 GATA binding protein 3 0.754527
CD19 CD19 molecule 0.752085
IL18BP interleukin 18 binding protein 0.751271
MYH9 myosin, heavy chain 9, non-muscle 0.749644
F3 coagulation factor III (thromboplastin, tissue factor) 0.74436
TBX21 T-box 21 0.710378
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.708767
EPSTI1 epithelial stromal interaction 1 (breast) 0.695905
HP haptoglobin 0.689893
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.687891
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.687491
HPR haptoglobin-related protein 0.683493
IFNA2 interferon, alpha 2 0.667947
IFRD1 interferon-related developmental regulator 1 0.659611
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.650903
GP1BB glycoprotein Ib (platelet), beta polypeptide 0.649323
KEL Kell blood group, metallo-endopeptidase 0.639857
CD52 CD52 molecule 0.638676
PLAC8 placenta-specific 8 0.634742
FOXP3 forkhead box P3 0.62885
POMP proteasome maturation protein 0.624143
TRIM37 tripartite motif containing 37 0.622183
INTS8 integrator complex subunit 8 0.6214
IGHV4-39 immunoglobulin heavy variable 4-39 0.594843
IL11 interleukin 11 0.585108
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.574994
SIGLEC7 sialic acid binding Ig-like lectin 7 0.568386
CD40 CD40 molecule, TNF receptor superfamily member 5 0.565666
SYK spleen tyrosine kinase 0.553627
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.540442
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.538893
POMC proopiomelanocortin 0.537731
RHCE Rh blood group, CcEe antigens 0.535796
CD80 CD80 molecule 0.534635
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.532314
IFNA1 interferon, alpha 1 0.529994
HLA-A major histocompatibility complex, class I, A 0.520346
FASLG Fas ligand (TNF superfamily, member 6) 0.501527
NCAM1 neural cell adhesion molecule 1 0.493885
PROS1 protein S (alpha) 0.474877
GRB2 growth factor receptor-bound protein 2 0.472982
IL2 interleukin 2 0.459751
DEFA3 defensin, alpha 3, neutrophil-specific 0.453339
F2 coagulation factor II (thrombin) 0.449571
GIF gastric intrinsic factor (vitamin B synthesis) 0.447311
TGFB1 transforming growth factor, beta 1 0.446558
ALB albumin 0.440162
CT45A1 cancer/testis antigen family 45, member A1 0.420266
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.414276
HLA-C major histocompatibility complex, class I, C 0.412779
CD96 CD96 molecule 0.410909
PF4 platelet factor 4 0.406798
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.405305
IL18 interleukin 18 0.378885
GP9 glycoprotein IX (platelet) 0.374809
CTPS1 CTP synthase 1 0.365562
DNASE1L3 deoxyribonuclease I-like 3 0.360764
IFI27 interferon, alpha-inducible protein 27 0.350452
IL6 interleukin 6 0.350084
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.348981
CD5 CD5 molecule 0.348614
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.348246
IGLV9-49 immunoglobulin lambda variable 9-49 0.341272
SBF2 SET binding factor 2 0.335778
CD34 CD34 molecule 0.32993
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.32701
GATA2 GATA binding protein 2 0.326281
RAN RAN, member RAS oncogene family 0.321545
APOH apolipoprotein H (beta-2-glycoprotein I) 0.320454
IL2RA interleukin 2 receptor, alpha 0.32009
CD36 CD36 molecule (thrombospondin receptor) 0.316456
CCNC cyclin C 0.313915
CD86 CD86 molecule 0.308118
MBD1 methyl-CpG binding domain protein 1 0.300533
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.299092
IL3 interleukin 3 0.294772
IGKV3-20 immunoglobulin kappa variable 3-20 0.289744
IFNG interferon, gamma 0.28616
GP6 glycoprotein VI (platelet) 0.283297
KAT8 K(lysine) acetyltransferase 8 0.281868
BCAM basal cell adhesion molecule (Lutheran blood group) 0.280796
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.279724
HOXB4 homeobox B4 0.272953
THBD thrombomodulin 0.267977
IL2RB interleukin 2 receptor, beta 0.266203
INSC inscuteable homolog (Drosophila) 0.244696
UST uronyl-2-sulfotransferase 0.239101
CD72 CD72 molecule 0.239101
AIRE autoimmune regulator 0.238403
SH3BP2 SH3-domain binding protein 2 0.226262
ALPPL2 alkaline phosphatase, placental-like 2 0.220766
ALPP alkaline phosphatase, placental 0.220424
ALPL alkaline phosphatase, liver/bone/kidney 0.21974
IL1RN interleukin 1 receptor antagonist 0.218034
IL4 interleukin 4 0.200006
CYS1 cystin 1 0.196139
RNF112 ring finger protein 112 0.193285
CD69 CD69 molecule 0.192657
LCK LCK proto-oncogene, Src family tyrosine kinase 0.191719
BCO1 beta-carotene oxygenase 1 0.188632
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.184424
UBIAD1 UbiA prenyltransferase domain containing 1 0.178403
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.173571
AGO2 argonaute RISC catalytic component 2 0.173571
MT3 metallothionein 3 0.169812
FKBP5 FK506 binding protein 5 0.163523
TNF tumor necrosis factor 0.163317
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.160948
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.144412
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.144335
PDLIM7 PDZ and LIM domain 7 (enigma) 0.141607
C3 complement component 3 0.1413
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.139984
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.139774
CD59 CD59 molecule, complement regulatory protein 0.138348
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.134581
ISG20 interferon stimulated exonuclease gene 20kDa 0.134408