primary lysosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A lysosome before it has fused with a vesicle or vacuole. (Gene Ontology, GO_0005766)
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Genes

95 proteins co-occuring with the primary lysosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MPO myeloperoxidase 2.46654
CTSG cathepsin G 2.13986
LTF lactotransferrin 2.00048
PRTN3 proteinase 3 1.98906
ELANE elastase, neutrophil expressed 1.70445
BPI bactericidal/permeability-increasing protein 1.55084
GUSB glucuronidase, beta 1.51807
ACPP acid phosphatase, prostate 1.47627
AZU1 azurocidin 1 1.46382
LYZ lysozyme 1.33359
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.15672
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.11939
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.992204
CLC Charcot-Leyden crystal galectin 0.97953
DEFA3 defensin, alpha 3, neutrophil-specific 0.949713
CD63 CD63 molecule 0.934544
KLK8 kallikrein-related peptidase 8 0.913909
C5AR1 complement component 5a receptor 1 0.830925
ALPPL2 alkaline phosphatase, placental-like 2 0.757707
ALPL alkaline phosphatase, liver/bone/kidney 0.757253
ALPP alkaline phosphatase, placental 0.756799
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.734217
PNN pinin, desmosome associated protein 0.681591
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.646145
IRF2BP1 interferon regulatory factor 2 binding protein 1 0.604017
LMX1B LIM homeobox transcription factor 1, beta 0.572162
DEFA4 defensin, alpha 4, corticostatin 0.542764
CLEC3B C-type lectin domain family 3, member B 0.523067
EPX eosinophil peroxidase 0.51694
LAMP2 lysosomal-associated membrane protein 2 0.5149
ANXA11 annexin A11 0.513677
HCK HCK proto-oncogene, Src family tyrosine kinase 0.50879
CTRL chymotrypsin-like 0.503506
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.488519
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.480453
SRGN serglycin 0.414946
CTSD cathepsin D 0.408699
FTL ferritin, light polypeptide 0.398587
FTH1 ferritin, heavy polypeptide 1 0.396648
STX3 syntaxin 3 0.381584
CD177 CD177 molecule 0.378122
LBP lipopolysaccharide binding protein 0.35899
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.358228
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.341151
RAB27B RAB27B, member RAS oncogene family 0.338128
CD34 CD34 molecule 0.334356
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.332472
IL5 interleukin 5 0.321575
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.307004
CAMP cathelicidin antimicrobial peptide 0.303655
SLPI secretory leukocyte peptidase inhibitor 0.302912
CSF3 colony stimulating factor 3 (granulocyte) 0.299197
IL11 interleukin 11 0.295119
C5ORF38 chromosome 5 open reading frame 38 0.289199
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.286614
ARSH arylsulfatase family, member H 0.281821
DNASE2 deoxyribonuclease II, lysosomal 0.281453
STX4 syntaxin 4 0.272633
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.254017
FGR FGR proto-oncogene, Src family tyrosine kinase 0.247854
CELA1 chymotrypsin-like elastase family, member 1 0.246769
MALL mal, T-cell differentiation protein-like 0.241716
VAMP8 vesicle-associated membrane protein 8 0.237401
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.236683
STXBP2 syntaxin binding protein 2 0.226686
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.226686
NCF2 neutrophil cytosolic factor 2 0.22385
CXCR1 chemokine (C-X-C motif) receptor 1 0.221025
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.220321
RBP3 retinol binding protein 3, interstitial 0.210549
ANXA1 annexin A1 0.210203
SNAP23 synaptosomal-associated protein, 23kDa 0.208481
MMP9 matrix metallopeptidase 9 0.208481
LAMP1 lysosomal-associated membrane protein 1 0.204718
CFD complement factor D (adipsin) 0.193719
PHB2 prohibitin 2 0.192423
TNF tumor necrosis factor 0.191777
FPR1 formyl peptide receptor 1 0.189857
CTSC cathepsin C 0.183935
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.183328
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.180339
CD69 CD69 molecule 0.179167
CYLD cylindromatosis (turban tumor syndrome) 0.174635
ACP2 acid phosphatase 2, lysosomal 0.174361
HLA-A major histocompatibility complex, class I, A 0.173814
STX2 syntaxin 2 0.171673
TG thyroglobulin 0.166167
ALB albumin 0.163865
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.16233
IL3 interleukin 3 0.161275
CAT catalase 0.158315
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.136863
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.136611
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.136536
CXCL8 chemokine (C-X-C motif) ligand 8 0.136056