primary effusion lymphoma cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Primary effusion lymphoma (PEL) is a peculiar type of B cell non-Hodgkin lymphoma (NHL) that has been recently recognized as an individual clinico-pathologic category based on the consistent infection of the tumor clone by human herpesvirus type-8 (HHV-8) and the distinctiveness of its clinical and biologic features. Although immunogenotypic studies have confirmed that PEL belongs in all cases to the B cell lineage, the overwhelming majority of cases exhibit a non-B, non-T (ie indeterminate) phenotype, lacking expression of surface immunoglobulins and common B cell associated antigens. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002719)
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Genes

116 proteins co-occuring with the tissue primary effusion lymphoma cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
VIL1 villin 1 1.97201
CHMP2A charged multivesicular body protein 2A 1.96514
FAM120C family with sequence similarity 120C 1.62307
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.17846
SECTM1 secreted and transmembrane 1 1.05765
SRP72 signal recognition particle 72kDa 0.956859
WARS tryptophanyl-tRNA synthetase 0.952116
IL6 interleukin 6 0.932766
CORO1C coronin, actin binding protein, 1C 0.931908
RPL34 ribosomal protein L34 0.896895
IRF4 interferon regulatory factor 4 0.838252
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.822339
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.788547
MNDA myeloid cell nuclear differentiation antigen 0.77027
KCP kielin/chordin-like protein 0.721988
DHFR dihydrofolate reductase 0.707221
CDK6 cyclin-dependent kinase 6 0.702308
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.687184
POU2AF1 POU class 2 associating factor 1 0.663555
CORO1A coronin, actin binding protein, 1A 0.648127
RNF31 ring finger protein 31 0.622639
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.585625
HAX1 HCLS1 associated protein X-1 0.580017
NUP153 nucleoporin 153kDa 0.578416
JAK3 Janus kinase 3 0.524771
FLT1 fms-related tyrosine kinase 1 0.523982
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.522405
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.511778
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.502357
BRD4 bromodomain containing 4 0.501965
ANG angiogenin, ribonuclease, RNase A family, 5 0.498832
IFNA1 interferon, alpha 1 0.497657
PAX5 paired box 5 0.471539
PABPC1 poly(A) binding protein, cytoplasmic 1 0.471539
RBSN rabenosyn, RAB effector 0.466111
DGCR8 DGCR8 microprocessor complex subunit 0.459918
CCND2 cyclin D2 0.459145
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.457214
DAXX death-domain associated protein 0.455284
BAD BCL2-associated agonist of cell death 0.442962
TSG101 tumor susceptibility 101 0.430312
PRDM1 PR domain containing 1, with ZNF domain 0.429547
DROSHA drosha, ribonuclease type III 0.428783
CDK4 cyclin-dependent kinase 4 0.425726
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.424581
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.407832
VEGFA vascular endothelial growth factor A 0.404418
TRAF1 TNF receptor-associated factor 1 0.402144
CDK2 cyclin-dependent kinase 2 0.40025
CD58 CD58 molecule 0.377996
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.377245
TP53 tumor protein p53 0.375368
SPI1 Spi-1 proto-oncogene 0.368624
ICAM1 intercellular adhesion molecule 1 0.36825
CCR8 chemokine (C-C motif) receptor 8 0.366007
ATN1 atrophin 1 0.362273
CD38 CD38 molecule 0.361155
PML promyelocytic leukemia 0.358919
BAX BCL2-associated X protein 0.355942
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.34371
VEGFB vascular endothelial growth factor B 0.342602
PTEN phosphatase and tensin homolog 0.331194
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.331194
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.325335
BCL6 B-cell CLL/lymphoma 6 0.322779
TYMS thymidylate synthetase 0.307528
TAT tyrosine aminotransferase 0.307167
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.301039
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.298883
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.295655
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.291365
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.290652
IRF7 interferon regulatory factor 7 0.275794
MAP2K1 mitogen-activated protein kinase kinase 1 0.256234
CYCS cytochrome c, somatic 0.250627
MGMT O-6-methylguanine-DNA methyltransferase 0.238108
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.229839
PDLIM7 PDZ and LIM domain 7 (enigma) 0.227707
CIITA class II, major histocompatibility complex, transactivator 0.227186
GSTA3 glutathione S-transferase alpha 3 0.223419
OSM oncostatin M 0.223419
GSTA4 glutathione S-transferase alpha 4 0.222224
GSTA2 glutathione S-transferase alpha 2 0.221989
CD2 CD2 molecule 0.220831
GSTA1 glutathione S-transferase alpha 1 0.219485
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.219485
BIRC2 baculoviral IAP repeat containing 2 0.217974
ICAM2 intercellular adhesion molecule 2 0.217762
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.217762
NOTCH1 notch 1 0.214388
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.187252
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.185593
PLAU plasminogen activator, urokinase 0.183481
CYGB cytoglobin 0.182455
RPS6 ribosomal protein S6 0.181168
HIST2H2AC histone cluster 2, H2ac 0.180822
HIST2H2AA3 histone cluster 2, H2aa3 0.180798
HIST2H2AA4 histone cluster 2, H2aa4 0.180798
KRT19 keratin 19, type I 0.179823
HNF1A HNF1 homeobox A 0.178975
CDKN2A cyclin-dependent kinase inhibitor 2A 0.176527
IL18 interleukin 18 0.175471
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.16909
ACTB actin, beta 0.165539
ACTG1 actin gamma 1 0.164012
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.163618
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.163144
B2M beta-2-microglobulin 0.156422
INSR insulin receptor 0.156337
HSPA4 heat shock 70kDa protein 4 0.152925
IL10 interleukin 10 0.152208
F8 coagulation factor VIII, procoagulant component 0.14776
ALB albumin 0.145914
IL4 interleukin 4 0.145362
CD68 CD68 molecule 0.144512
TF transferrin 0.139642