primary cilium Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cilium found on many different cell types that is typically present in a single copy per cell. A primary cilium may have a variable array of axonemal microtubules and may or may not contain molecular motors. (Gene Ontology, GO_0072372)
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Genes

138 proteins localized to the primary cilium cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SPTBN5 spectrin, beta, non-erythrocytic 5 0.663342
RPGR retinitis pigmentosa GTPase regulator 0.663342
RAB8A RAB8A, member RAS oncogene family 0.663342
ODF2 outer dense fiber of sperm tails 2 0.663342
NPHP3 nephronophthisis 3 (adolescent) 0.663342
PARD3 par-3 family cell polarity regulator 0.663342
CEP41 centrosomal protein 41kDa 0.663342
TULP3 tubby like protein 3 0.663342
MYO7A myosin VIIA 0.663342
TBCC tubulin folding cofactor C 0.663342
RAB10 RAB10, member RAS oncogene family 0.663342
UNC119B unc-119 homolog B (C. elegans) 0.663342
PKD1L1 polycystic kidney disease 1 like 1 0.663342
UMOD uromodulin 0.663342
CCSAP centriole, cilia and spindle-associated protein 0.663342
OCRL oculocerebrorenal syndrome of Lowe 0.663342
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.663342
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.663342
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 0.663342
AHI1 Abelson helper integration site 1 0.663342
PKD2L1 polycystic kidney disease 2-like 1 0.663342
TBC1D30 TBC1 domain family, member 30 0.663342
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.663342
C5ORF30 chromosome 5 open reading frame 30 0.663342
FAM161A family with sequence similarity 161, member A 0.663342
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.663342
ARL13B ADP-ribosylation factor-like 13B 0.663342
TMEM237 transmembrane protein 237 0.663342
RP1 retinitis pigmentosa 1 (autosomal dominant) 0.663342
C2ORF71 chromosome 2 open reading frame 71 0.663342
RAB15 RAB15, member RAS oncogene family 0.663342
RHO rhodopsin 0.663342
ARL3 ADP-ribosylation factor-like 3 0.663342
RAB8B RAB8B, member RAS oncogene family 0.663342
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.237908
SMO smoothened, frizzled class receptor 0.237908
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.237908
TMEM216 transmembrane protein 216 0.237908
TMEM17 transmembrane protein 17 0.237908
IFT122 intraflagellar transport 122 0.237908
IQCB1 IQ motif containing B1 0.237908
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.237908
GUCA1B guanylate cyclase activator 1B (retina) 0.237908
GRXCR1 glutaredoxin, cysteine rich 1 0.237908
GPR161 G protein-coupled receptor 161 0.237908
BBS4 Bardet-Biedl syndrome 4 0.237908
MAK male germ cell-associated kinase 0.237908
NPHP1 nephronophthisis 1 (juvenile) 0.237908
TMEM231 transmembrane protein 231 0.237908
SPA17 sperm autoantigenic protein 17 0.237908
PROM1 prominin 1 0.237908
GUCA1C guanylate cyclase activator 1C 0.237908
GUCA1A guanylate cyclase activator 1A (retina) 0.237908
GUCY2F guanylate cyclase 2F, retinal 0.237908
CC2D2A coiled-coil and C2 domain containing 2A 0.237908
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.237908
CEP290 centrosomal protein 290kDa 0.237908
RP1L1 retinitis pigmentosa 1-like 1 0.237908
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.237908
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.237908
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 0.237908
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.237908
PDE4C phosphodiesterase 4C, cAMP-specific 0.237908
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.237908
RILPL2 Rab interacting lysosomal protein-like 2 0.237908
NEK8 NIMA-related kinase 8 0.237908
TTBK2 tau tubulin kinase 2 0.237908
TCTN2 tectonic family member 2 0.237908
PCDH15 protocadherin-related 15 0.237908
KIF3A kinesin family member 3A 0.237908
TCTN1 tectonic family member 1 0.237908
STRCP1 stereocilin pseudogene 1 0.237908
B9D1 B9 protein domain 1 0.237908
TMEM67 transmembrane protein 67 0.237908
GRK1 G protein-coupled receptor kinase 1 0.237908
TULP1 tubby like protein 1 0.237908
RILPL1 Rab interacting lysosomal protein-like 1 0.237908
STRC stereocilin 0.237908
MKS1 Meckel syndrome, type 1 0.237908
TTC26 tetratricopeptide repeat domain 26 0.237908
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.237908
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.237908
ADCY5 adenylate cyclase 5 0.237908
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.237908
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 0.237908
WDR19 WD repeat domain 19 0.237908
B9D2 B9 protein domain 2 0.237908
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.098109
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.098109
MCHR1 melanin-concentrating hormone receptor 1 0.098109
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.098109
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.098109
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.098109
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.098109
SSTR3 somatostatin receptor 3 0.098109
GLI1 GLI family zinc finger 1 0.03318
GLI3 GLI family zinc finger 3 0.03318
GLI2 GLI family zinc finger 2 0.03318
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.03318
PRKCA protein kinase C, alpha 0.03318
IFT46 intraflagellar transport 46 0.03318
ROM1 retinal outer segment membrane protein 1 0.03318
CETN1 centrin, EF-hand protein, 1 0.03318
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.03318
CNGA1 cyclic nucleotide gated channel alpha 1 0.03318
MYRIP myosin VIIA and Rab interacting protein 0.03318
MYO5A myosin VA (heavy chain 12, myoxin) 0.03318
IFT57 intraflagellar transport 57 0.03318
IFT88 intraflagellar transport 88 0.03318
PDC phosducin 0.03318
IFT52 intraflagellar transport 52 0.03318
SAG S-antigen; retina and pineal gland (arrestin) 0.03318
TUBG1 tubulin, gamma 1 0.03318
CNGA3 cyclic nucleotide gated channel alpha 3 0.03318
NPHP4 nephronophthisis 4 0.03318
KCTD10 potassium channel tetramerization domain containing 10 0.03318
RAB27A RAB27A, member RAS oncogene family 0.03318
CETN3 centrin, EF-hand protein, 3 0.03318
MYO3B myosin IIIB 0.03318
PTCH1 patched 1 0.03318
INHA inhibin, alpha 0.03318
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.03318
SEPT2 septin 2 0.03318
MERTK MER proto-oncogene, tyrosine kinase 0.03318
CDHR1 cadherin-related family member 1 0.03318
KNCN kinocilin 0.03318
CETN2 centrin, EF-hand protein, 2 0.03318
TTC8 tetratricopeptide repeat domain 8 0.03318
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.03318
SUFU suppressor of fused homolog (Drosophila) 0.03318
IFT20 intraflagellar transport 20 0.03318
PTPRK protein tyrosine phosphatase, receptor type, K 0.03318
IFT140 intraflagellar transport 140 0.03318
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.03318
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.03318
PRPH peripherin 0.03318
CNGB3 cyclic nucleotide gated channel beta 3 0.03318
ARR3 arrestin 3, retinal (X-arrestin) 0.03318