primary bacterial infectious disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread. (Human Disease Ontology, DOID_0050338)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:0050338
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Genes

121 genes associated with the disease primary bacterial infectious disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.95157
CCDC122 coiled-coil domain containing 122 1.59537
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.30255
RIPK2 receptor-interacting serine-threonine kinase 2 1.05823
FILIP1 filamin A interacting protein 1 0.998812
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.677449
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.465051
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.461977
HLA-C major histocompatibility complex, class I, C 0.458853
HLA-DRA major histocompatibility complex, class II, DR alpha 0.457561
C2CD2 C2 calcium-dependent domain containing 2 0.456271
IL2RB interleukin 2 receptor, beta 0.456271
HLA-DOB major histocompatibility complex, class II, DO beta 0.454924
STXBP5 syntaxin binding protein 5 (tomosyn) 0.438494
MATN4 matrilin 4 0.430604
CDH13 cadherin 13 0.430311
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 0.430311
DSCAM Down syndrome cell adhesion molecule 0.430311
PARD3B par-3 family cell polarity regulator beta 0.430311
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.427916
ALS2CL ALS2 C-terminal like 0.427592
DUSP14 dual specificity phosphatase 14 0.425585
ZFPM2 zinc finger protein, FOG family member 2 0.425585
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 0.425585
SEPHS1 selenophosphate synthetase 1 0.424562
ZNF229 zinc finger protein 229 0.422054
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.422054
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.420323
DHDDS dehydrodolichyl diphosphate synthase 0.419457
VWA8 von Willebrand factor A domain containing 8 0.419335
SH3GL2 SH3-domain GRB2-like 2 0.419023
MYO1D myosin ID 0.418223
C6ORF15 chromosome 6 open reading frame 15 0.417246
ASTN2 astrotactin 2 0.417062
CHN1 chimerin 1 0.415589
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.414949
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.414832
UPP2 uridine phosphorylase 2 0.414736
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.41363
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.411862
IL23R interleukin 23 receptor 0.411816
AHCYL2 adenosylhomocysteinase-like 2 0.411526
SPON1 spondin 1, extracellular matrix protein 0.411526
FHIT fragile histidine triad 0.410581
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.409312
CD226 CD226 molecule 0.407981
MECOM MDS1 and EVI1 complex locus 0.406711
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.405762
TRDN triadin 0.405087
AKNAD1 AKNA domain containing 1 0.404654
ACBD6 acyl-CoA binding domain containing 6 0.404548
DNAH11 dynein, axonemal, heavy chain 11 0.404442
NTNG1 netrin G1 0.404027
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.402472
OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.402472
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.401404
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.400981
C6ORF10 chromosome 6 open reading frame 10 0.399857
PTPRD protein tyrosine phosphatase, receptor type, D 0.397768
XYLT1 xylosyltransferase I 0.397371
NCKAP5 NCK-associated protein 5 0.397048
UBXN11 UBX domain protein 11 0.396908
ANO2 anoctamin 2, calcium activated chloride channel 0.39654
SAMD4A sterile alpha motif domain containing 4A 0.395757
BMPER BMP binding endothelial regulator 0.39555
UBASH3B ubiquitin associated and SH3 domain containing B 0.395481
ACTG1 actin gamma 1 0.394484
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.393913
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.39324
PLS1 plastin 1 0.393061
RBL2 retinoblastoma-like 2 0.391968
LOC100129620 uncharacterized LOC100129620 0.391913
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.391367
COL12A1 collagen, type XII, alpha 1 0.3911
SDK1 sidekick cell adhesion molecule 1 0.391047
AKR1C3 aldo-keto reductase family 1, member C3 0.390994
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.390528
FBLN1 fibulin 1 0.390528
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.390426
LRRC7 leucine rich repeat containing 7 0.389827
UBA6 ubiquitin-like modifier activating enzyme 6 0.389583
ERBB4 erb-b2 receptor tyrosine kinase 4 0.389487
KLF12 Kruppel-like factor 12 0.389295
HUNK hormonally up-regulated Neu-associated kinase 0.389106
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.389059
PARD3 par-3 family cell polarity regulator 0.389013
NPAS3 neuronal PAS domain protein 3 0.388103
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.388103
LEKR1 leucine, glutamate and lysine rich 1 0.387926
CSMD1 CUB and Sushi multiple domains 1 0.387883
REPS2 RALBP1 associated Eps domain containing 2 0.385408
VSTM2A V-set and transmembrane domain containing 2A 0.385146
SGMS1 sphingomyelin synthase 1 0.385035
SOX6 SRY (sex determining region Y)-box 6 0.384779
TMEM51 transmembrane protein 51 0.384562
ZNF318 zinc finger protein 318 0.383409
C17ORF78 chromosome 17 open reading frame 78 0.383334
RAI14 retinoic acid induced 14 0.382459
NOD2 nucleotide-binding oligomerization domain containing 2 0.382001
IGSF21 immunoglobin superfamily, member 21 0.380726
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.378529
LRP1B low density lipoprotein receptor-related protein 1B 0.377522
GEMIN7 gem (nuclear organelle) associated protein 7 0.376491
SCD5 stearoyl-CoA desaturase 5 0.37616
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.375662
FGD6 FYVE, RhoGEF and PH domain containing 6 0.375345
MRRF mitochondrial ribosome recycling factor 0.374916
EYA2 EYA transcriptional coactivator and phosphatase 2 0.373952
SLIT3 slit homolog 3 (Drosophila) 0.37362
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.372846
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.3727
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.372575
DNAH8 dynein, axonemal, heavy chain 8 0.372472
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.371924
LGMN legumain 0.371028
CCDC148 coiled-coil domain containing 148 0.36942
LHFP lipoma HMGIC fusion partner 0.368523
LRP2 low density lipoprotein receptor-related protein 2 0.349147
RANBP3L RAN binding protein 3-like 0.343689
ERP44 endoplasmic reticulum protein 44 0.339636
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.336889