primary angle-closure glaucoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

79 genes co-occuring with the disease primary angle-closure glaucoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PLEKHA7 pleckstrin homology domain containing, family A member 7 2.26797
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2.22019
ST18 suppression of tumorigenicity 18, zinc finger 2.04596
COL11A1 collagen, type XI, alpha 1 1.66645
CTSA cathepsin A 1.44298
MFRP membrane frizzled-related protein 1.42498
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.30663
CALCRL calcitonin receptor-like 1.149
PDIA5 protein disulfide isomerase family A, member 5 1.14136
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.09419
RAB22A RAB22A, member RAS oncogene family 1.09419
OPTN optineurin 1.02397
WDR36 WD repeat domain 36 1.02313
NTF4 neurotrophin 4 1.01512
PYDC1 PYD (pyrin domain) containing 1 0.999503
BIRC6 baculoviral IAP repeat containing 6 0.768801
MMP9 matrix metallopeptidase 9 0.768393
EYS eyes shut homolog (Drosophila) 0.761454
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.75412
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.752492
VAV2 vav 2 guanine nucleotide exchange factor 0.74761
LOXL1 lysyl oxidase-like 1 0.746798
MT-ATP8 ATP synthase F0 subunit 8 0.715215
VAV3 vav 3 guanine nucleotide exchange factor 0.684692
AQP7 aquaporin 7 0.67312
TGFB2 transforming growth factor, beta 2 0.666755
AXL AXL receptor tyrosine kinase 0.65763
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.654067
LTBP3 latent transforming growth factor beta binding protein 3 0.652089
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.620617
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.618268
HINT1 histidine triad nucleotide binding protein 1 0.618268
LTBP2 latent transforming growth factor beta binding protein 2 0.613965
VSX2 visual system homeobox 2 0.610838
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.608494
PEX19 peroxisomal biogenesis factor 19 0.594064
RSPO1 R-spondin 1 0.58433
SZRD1 SUZ RNA binding domain containing 1 0.562169
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.561392
SLC22A18 solute carrier family 22, member 18 0.559839
NLRP1 NLR family, pyrin domain containing 1 0.554015
ALPI alkaline phosphatase, intestinal 0.487407
TXNRD2 thioredoxin reductase 2 0.459373
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.454093
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.451831
MMP1 matrix metallopeptidase 1 0.433021
PDE5A phosphodiesterase 5A, cGMP-specific 0.431144
GPR182 G protein-coupled receptor 182 0.429642
AQP5 aquaporin 5 0.419892
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.407545
TIMP1 TIMP metallopeptidase inhibitor 1 0.402692
MMP2 matrix metallopeptidase 2 0.395235
FRZB frizzled-related protein 0.393001
AQP3 aquaporin 3 (Gill blood group) 0.386308
TIMP2 TIMP metallopeptidase inhibitor 2 0.339073
CSTB cystatin B (stefin B) 0.337608
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.280796
SFRP1 secreted frizzled-related protein 1 0.264077
TGFB3 transforming growth factor, beta 3 0.255946
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.213959
EDN1 endothelin 1 0.209583
NLRP3 NLR family, pyrin domain containing 3 0.189551
CRYAB crystallin, alpha B 0.184424
GJA1 gap junction protein, alpha 1, 43kDa 0.184424
HPGDS hematopoietic prostaglandin D synthase 0.175411
DNTT DNA nucleotidylexotransferase 0.173571
MNX1 motor neuron and pancreas homeobox 1 0.164149
TARDBP TAR DNA binding protein 0.15948
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.146107
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.145477
DNM2 dynamin 2 0.142046
ADM adrenomedullin 0.140452
AQP4 aquaporin 4 0.139537
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.139072
CARD17 caspase recruitment domain family, member 17 0.138843
PLAT plasminogen activator, tissue 0.138367
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.133389
F8 coagulation factor VIII, procoagulant component 0.130329
TLR4 toll-like receptor 4 0.130003