primaquine-4263 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the primaquine-4263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACRV1 acrosomal vesicle protein 1
AGXT alanine-glyoxylate aminotransferase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
BHLHE40 basic helix-loop-helix family, member e40
BTG2 BTG family, member 2
C1ORF54 chromosome 1 open reading frame 54
CAMTA1 calmodulin binding transcription activator 1
CASS4 Cas scaffolding protein family member 4
CCL23 chemokine (C-C motif) ligand 23
CDHR5 cadherin-related family member 5
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CKM creatine kinase, muscle
CLCA2 chloride channel accessory 2
CSDC2 cold shock domain containing C2, RNA binding
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DEFB4A defensin, beta 4A
DRP2 dystrophin related protein 2
DUSP1 dual specificity phosphatase 1
EDA ectodysplasin A
EDN3 endothelin 3
EDRF1 erythroid differentiation regulatory factor 1
EMILIN1 elastin microfibril interfacer 1
EPHA7 EPH receptor A7
ESR1 estrogen receptor 1
FGA fibrinogen alpha chain
FGF6 fibroblast growth factor 6
FOXP3 forkhead box P3
FRS2 fibroblast growth factor receptor substrate 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
HOXD13 homeobox D13
HRG histidine-rich glycoprotein
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IFNA6 interferon, alpha 6
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGSF1 immunoglobulin superfamily, member 1
IL1RN interleukin 1 receptor antagonist
IL21 interleukin 21
INS insulin
ITGB7 integrin, beta 7
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLF6 Kruppel-like factor 6
KRT16 keratin 16, type I
KRT17 keratin 17, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LSAMP limbic system-associated membrane protein
MAN1C1 mannosidase, alpha, class 1C, member 1
MTMR8 myotubularin related protein 8
MYCNOS MYCN opposite strand
MYO1B myosin IB
MYT1 myelin transcription factor 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NIPAL3 NIPA-like domain containing 3
NME8 NME/NM23 family member 8
NRXN2 neurexin 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OTOF otoferlin
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCSK6 proprotein convertase subtilisin/kexin type 6
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB4 proline-rich protein BstNI subfamily 4
PRDM14 PR domain containing 14
PRDM9 PR domain containing 9
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RCE1 Ras converting CAAX endopeptidase 1
REPS1 RALBP1 associated Eps domain containing 1
RFPL1 ret finger protein-like 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC17A4 solute carrier family 17, member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SNED1 sushi, nidogen and EGF-like domains 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STK3 serine/threonine kinase 3
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TK2 thymidine kinase 2, mitochondrial
TMPRSS4 transmembrane protease, serine 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM2 tropomyosin 2 (beta)
TRIM31 tripartite motif containing 31
TTLL1 tubulin tyrosine ligase-like family member 1
WIPF1 WAS/WASL interacting protein family, member 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF814 zinc finger protein 814

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADCY6 adenylate cyclase 6
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANP32A-IT1 ANP32A intronic transcript 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGAP11A Rho GTPase activating protein 11A
ARL14 ADP-ribosylation factor-like 14
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C22ORF29 chromosome 22 open reading frame 29
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CARD8 caspase recruitment domain family, member 8
CCS copper chaperone for superoxide dismutase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CISH cytokine inducible SH2-containing protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUZD1 CUB and zona pellucida-like domains 1
CXADR coxsackie virus and adenovirus receptor
DCAF4 DDB1 and CUL4 associated factor 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHODH dihydroorotate dehydrogenase (quinone)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNA2 DNA replication helicase/nuclease 2
EFNA3 ephrin-A3
EPHB3 EPH receptor B3
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM69A family with sequence similarity 69, member A
GDAP1 ganglioside induced differentiation associated protein 1
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GPALPP1 GPALPP motifs containing 1
GPR4 G protein-coupled receptor 4
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSAP gamma-secretase activating protein
HIST1H2AM histone cluster 1, H2am
HIST1H4E histone cluster 1, H4e
HMHA1 histocompatibility (minor) HA-1
HOXA5 homeobox A5
HSPA2 heat shock 70kDa protein 2
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI35 interferon-induced protein 35
INCENP inner centromere protein antigens 135/155kDa
ISL1 ISL LIM homeobox 1
ITPKB inositol-trisphosphate 3-kinase B
KATNBL1 katanin p80 subunit B-like 1
KIAA1462 KIAA1462
LIG4 ligase IV, DNA, ATP-dependent
LPAR6 lysophosphatidic acid receptor 6
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MBTPS2 membrane-bound transcription factor peptidase, site 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NDP Norrie disease (pseudoglioma)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARD6A par-6 family cell polarity regulator alpha
PCOLCE procollagen C-endopeptidase enhancer
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTCD2 pentatricopeptide repeat domain 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RIN1 Ras and Rab interactor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SGMS1 sphingomyelin synthase 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35F6 solute carrier family 35, member F6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPEG SPEG complex locus
TEX40 testis expressed 40
THBS3 thrombospondin 3
TMEM168 transmembrane protein 168
TPST1 tyrosylprotein sulfotransferase 1
TWISTNB TWIST neighbor
TXLNG taxilin gamma
USP27X ubiquitin specific peptidase 27, X-linked
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF189 zinc finger protein 189
ZNF200 zinc finger protein 200
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF33B zinc finger protein 33B
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552
ZNF606 zinc finger protein 606
ZNF696 zinc finger protein 696
ZNRD1-AS1 ZNRD1 antisense RNA 1