prilocaine-2314 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the prilocaine-2314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AKAP7 A kinase (PRKA) anchor protein 7
ALPK1 alpha-kinase 1
B9D2 B9 protein domain 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAN brevican
BGN biglycan
BMP6 bone morphogenetic protein 6
BTF3P11 basic transcription factor 3 pseudogene 11
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF59 chromosome 17 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
CADM3 cell adhesion molecule 3
CARTPT CART prepropeptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCKBR cholecystokinin B receptor
CCRL2 chemokine (C-C motif) receptor-like 2
CD58 CD58 molecule
CD82 CD82 molecule
CD8A CD8a molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHD5 chromodomain helicase DNA binding protein 5
CNTFR ciliary neurotrophic factor receptor
CREM cAMP responsive element modulator
CRYGD crystallin, gamma D
DLK1 delta-like 1 homolog (Drosophila)
EFNB3 ephrin-B3
EPHB2 EPH receptor B2
FADS2 fatty acid desaturase 2
FLJ21369 uncharacterized protein FLJ21369
GAB1 GRB2-associated binding protein 1
GRM2 glutamate receptor, metabotropic 2
GSTA3 glutathione S-transferase alpha 3
GYG2 glycogenin 2
HIST1H2BL histone cluster 1, H2bl
HOXA10 homeobox A10
HSPG2 heparan sulfate proteoglycan 2
IL1B interleukin 1, beta
JAM3 junctional adhesion molecule 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD12 potassium channel tetramerization domain containing 12
KRAS Kirsten rat sarcoma viral oncogene homolog
KREMEN2 kringle containing transmembrane protein 2
KRT6B keratin 6B, type II
LAPTM5 lysosomal protein transmembrane 5
MAG myelin associated glycoprotein
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED25 mediator complex subunit 25
MEG3 maternally expressed 3 (non-protein coding)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP25 matrix metallopeptidase 25
MST1L macrophage stimulating 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR2 natriuretic peptide receptor 2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PARD3 par-3 family cell polarity regulator
PCNX pecanex homolog (Drosophila)
PDGFB platelet-derived growth factor beta polypeptide
PDLIM3 PDZ and LIM domain 3
PHF8 PHD finger protein 8
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXND1 plexin D1
POMT2 protein-O-mannosyltransferase 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PTHLH parathyroid hormone-like hormone
PTRF polymerase I and transcript release factor
RASL11B RAS-like, family 11, member B
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RTN2 reticulon 2
S100A13 S100 calcium binding protein A13
SCRN3 secernin 3
SLC17A2 solute carrier family 17, member 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STAC SH3 and cysteine rich domain
TCHH trichohyalin
TGFB2 transforming growth factor, beta 2
THY1 Thy-1 cell surface antigen
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53I11 tumor protein p53 inducible protein 11
TRIM29 tripartite motif containing 29
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSC22D2 TSC22 domain family, member 2
VIPR1 vasoactive intestinal peptide receptor 1
YIPF2 Yip1 domain family, member 2
ZBTB17 zinc finger and BTB domain containing 17
ZC3H7B zinc finger CCCH-type containing 7B
ZNF155 zinc finger protein 155
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGBL2 ATP/GTP binding protein-like 2
AMPD1 adenosine monophosphate deaminase 1
ATP13A2 ATPase type 13A2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL9 B-cell CLL/lymphoma 9
C11ORF21 chromosome 11 open reading frame 21
C3 complement component 3
C3ORF18 chromosome 3 open reading frame 18
C9ORF9 chromosome 9 open reading frame 9
CAPN15 calpain 15
CCDC25 coiled-coil domain containing 25
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK18 cyclin-dependent kinase 18
CENPT centromere protein T
CGA glycoprotein hormones, alpha polypeptide
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRMP1 collapsin response mediator protein 1
DEFA4 defensin, alpha 4, corticostatin
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP13 dual specificity phosphatase 13
EGFL7 EGF-like-domain, multiple 7
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM63A family with sequence similarity 63, member A
FBXO2 F-box protein 2
FKBP5 FK506 binding protein 5
FOXI1 forkhead box I1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLI3 GLI family zinc finger 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4A histone cluster 1, H4a
HIST1H4F histone cluster 1, H4f
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC10 homeobox C10
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT140 intraflagellar transport 140
IGSF1 immunoglobulin superfamily, member 1
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAGEB2 melanoma antigen family B2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFSD11 major facilitator superfamily domain containing 11
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA6 protocadherin alpha 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCH pro-melanin-concentrating hormone
PMEL premelanosome protein
QSER1 glutamine and serine rich 1
RAB3D RAB3D, member RAS oncogene family
RLN1 relaxin 1
RNF122 ring finger protein 122
ROM1 retinal outer segment membrane protein 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNTA1 syntrophin, alpha 1
STIM1 stromal interaction molecule 1
SYNC syncoilin, intermediate filament protein
TFF2 trefoil factor 2
TLR5 toll-like receptor 5
TMEM242 transmembrane protein 242
USP27X ubiquitin specific peptidase 27, X-linked
ZBTB6 zinc finger and BTB domain containing 6
ZFP37 ZFP37 zinc finger protein
ZNF282 zinc finger protein 282
ZNF350 zinc finger protein 350
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26