prednisolone-7424 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the prednisolone-7424 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AK1 adenylate kinase 1
AKR1C2 aldo-keto reductase family 1, member C2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP3 aquaporin 3 (Gill blood group)
C19ORF73 chromosome 19 open reading frame 73
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COMT catechol-O-methyltransferase
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CORT cortistatin
CPD carboxypeptidase D
CREBZF CREB/ATF bZIP transcription factor
CYLD cylindromatosis (turban tumor syndrome)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DESI2 desumoylating isopeptidase 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOK4 docking protein 4
DUSP13 dual specificity phosphatase 13
EGR3 early growth response 3
EPS8L1 EPS8-like 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FAAH fatty acid amide hydrolase
FADS3 fatty acid desaturase 3
FBXO38 F-box protein 38
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLOT1 flotillin 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GLE1 GLE1 RNA export mediator
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
IFIH1 interferon induced with helicase C domain 1
JMJD4 jumonji domain containing 4
JUN jun proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
KHSRP KH-type splicing regulatory protein
KIAA0930 KIAA0930
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMO4 LIM domain only 4
LRRC14 leucine rich repeat containing 14
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP7D3 MAP7 domain containing 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MBD1 methyl-CpG binding domain protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
N4BP3 NEDD4 binding protein 3
NAAA N-acylethanolamine acid amidase
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NPFFR1 neuropeptide FF receptor 1
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDE4C phosphodiesterase 4C, cAMP-specific
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPT2 palmitoyl-protein thioesterase 2
PRLR prolactin receptor
PTRF polymerase I and transcript release factor
RAD51B RAD51 paralog B
RANBP3 RAN binding protein 3
RGS12 regulator of G-protein signaling 12
RGS2 regulator of G-protein signaling 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIRT3 sirtuin 3
SMIM14 small integral membrane protein 14
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTA1 syntrophin, alpha 1
SPDEF SAM pointed domain containing ETS transcription factor
SSPN sarcospan
STK17B serine/threonine kinase 17b
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D22A TBC1 domain family, member 22A
TBX5 T-box 5
TGFB3 transforming growth factor, beta 3
THBD thrombomodulin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA4B tubulin, alpha 4b
UBOX5 U-box domain containing 5
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB1 zinc finger and BTB domain containing 1
ZNF444 zinc finger protein 444
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
AKR1C3 aldo-keto reductase family 1, member C3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP11A Rho GTPase activating protein 11A
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG4A autophagy related 4A, cysteine peptidase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCL7B B-cell CLL/lymphoma 7B
BRPF1 bromodomain and PHD finger containing, 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CAPN5 calpain 5
CCDC9 coiled-coil domain containing 9
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIC capicua transcriptional repressor
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSC cathepsin C
DEAF1 DEAF1 transcription factor
DSCAM Down syndrome cell adhesion molecule
DTX4 deltex 4, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM131A family with sequence similarity 131, member A
FAM193B family with sequence similarity 193, member B
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FZD4 frizzled class receptor 4
GAB2 GRB2-associated binding protein 2
GAREM GRB2 associated, regulator of MAPK1
GLI3 GLI family zinc finger 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRB7 growth factor receptor-bound protein 7
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
IRF7 interferon regulatory factor 7
KRT86 keratin 86, type II
LAMA3 laminin, alpha 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00115 long intergenic non-protein coding RNA 115
LMCD1 LIM and cysteine-rich domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC37A2 leucine rich repeat containing 37, member A2
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD11 major facilitator superfamily domain containing 11
MMD monocyte to macrophage differentiation-associated
MTCL1 microtubule crosslinking factor 1
MUM1 melanoma associated antigen (mutated) 1
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NINL ninein-like
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PEX26 peroxisomal biogenesis factor 26
PKN1 protein kinase N1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PRKX protein kinase, X-linked
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB20 RAB20, member RAS oncogene family
RBM23 RNA binding motif protein 23
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SHPK sedoheptulokinase
SIK1 salt-inducible kinase 1
SLC22A18 solute carrier family 22, member 18
SNHG3 small nucleolar RNA host gene 3
SP140L SP140 nuclear body protein-like
SPAG7 sperm associated antigen 7
STBD1 starch binding domain 1
TCTN2 tectonic family member 2
TESK2 testis-specific kinase 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM39B transmembrane protein 39B
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC13 trafficking protein particle complex 13
TSC22D4 TSC22 domain family, member 4
TTC17 tetratricopeptide repeat domain 17
TUBA4A tubulin, alpha 4a
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
YEATS2 YEATS domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT5 zinc finger, matrin-type 5
ZNF365 zinc finger protein 365