precursor cell lymphoblastic leukemia-lymphoma Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cancer (Genetic Association Database)
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Genes

106 genes associated with the disease precursor cell lymphoblastic leukemia-lymphoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM33 ADAM metallopeptidase domain 33
ADRB2 adrenoceptor beta 2, surface
ARID5B AT rich interactive domain 5B (MRF1-like)
BAG6 BCL2-associated athanogene 6
CCND1 cyclin D1
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD80 CD80 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CRHR1 corticotropin releasing hormone receptor 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAXX death-domain associated protein
DDR1 discoidin domain receptor tyrosine kinase 1
DGKB diacylglycerol kinase, beta 90kDa
DHFR dihydrofolate reductase
ELMO1 engulfment and cell motility 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLT3 fms-related tyrosine kinase 3
GATA3 GATA binding protein 3
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IER3 immediate early response 3
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK1 Janus kinase 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LMBRD2 LMBR1 domain containing 2
LTA lymphotoxin alpha
MAML2 mastermind-like 2 (Drosophila)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MME membrane metallo-endopeptidase
MPO myeloperoxidase
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTAP methylthioadenosine phosphorylase
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUTYH mutY homolog
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCOA3 nuclear receptor coactivator 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OGG1 8-oxoguanine DNA glycosylase
PHF11 PHD finger protein 11
PRF1 perforin 1 (pore forming protein)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
RFC1 replication factor C (activator 1) 1, 145kDa
RUNX1 runt-related transcription factor 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUGCT succinyl-CoA:glutarate-CoA transferase
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TP53 tumor protein p53
TP63 tumor protein p63
TPMT thiopurine S-methyltransferase
TYMS thymidylate synthetase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XDH xanthine dehydrogenase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1