pre-malignant neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer. (Human Disease Ontology, DOID_0060071)
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Genes

573 genes co-occuring with the disease pre-malignant neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ERBB2 erb-b2 receptor tyrosine kinase 2 2.33188
ESR1 estrogen receptor 1 2.13516
PGR progesterone receptor 2.01157
TP53 tumor protein p53 1.84136
KRT5 keratin 5, type II 1.65834
EGFR epidermal growth factor receptor 1.47374
CDKN2A cyclin-dependent kinase inhibitor 2A 1.46363
S100A7 S100 calcium binding protein A7 1.41753
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.38166
BRCA1 breast cancer 1, early onset 1.31668
KRT14 keratin 14, type I 1.29309
PDPN podoplanin 1.25471
CCND1 cyclin D1 1.25341
BRCA2 breast cancer 2, early onset 1.22172
KRT8 keratin 8, type II 1.1588
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.05976
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.0168
KRT80 keratin 80, type II 1.01469
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.980952
GP5 glycoprotein V (platelet) 0.956196
PCNA proliferating cell nuclear antigen 0.93497
PIP prolactin-induced protein 0.906498
ESR2 estrogen receptor 2 (ER beta) 0.891718
TRAF4 TNF receptor-associated factor 4 0.847898
CD44 CD44 molecule (Indian blood group) 0.843392
MKI67 marker of proliferation Ki-67 0.811001
GP6 glycoprotein VI (platelet) 0.81059
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) 0.792541
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.782298
MYH11 myosin, heavy chain 11, smooth muscle 0.775341
HRAS Harvey rat sarcoma viral oncogene homolog 0.774523
KRT7 keratin 7, type II 0.77207
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.740299
SYP synaptophysin 0.735838
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.732596
MUC1 mucin 1, cell surface associated 0.730976
CDH13 cadherin 13 0.72127
CD68 CD68 molecule 0.720058
TLR7 toll-like receptor 7 0.717232
AR androgen receptor 0.71078
ANAPC13 anaphase promoting complex subunit 13 0.705144
S100A9 S100 calcium binding protein A9 0.699517
CST6 cystatin E/M 0.691896
AAMP angio-associated, migratory cell protein 0.688692
SCGB3A1 secretoglobin, family 3A, member 1 0.669936
MORF4L2 mortality factor 4 like 2 0.66755
HBA2 hemoglobin, alpha 2 0.66596
CA9 carbonic anhydrase IX 0.662784
SFN stratifin 0.658026
MMP2 matrix metallopeptidase 2 0.654067
C11ORF30 chromosome 11 open reading frame 30 0.650113
NYNRIN NYN domain and retroviral integrase containing 0.647743
KLK10 kallikrein-related peptidase 10 0.647348
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 0.641433
HBA1 hemoglobin, alpha 1 0.641039
KRT20 keratin 20, type I 0.639463
PRDM14 PR domain containing 14 0.633169
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.622575
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.621008
FHIT fragile histidine triad 0.619834
SNX24 sorting nexin 24 0.617877
BCL2 B-cell CLL/lymphoma 2 0.612792
KIAA1671 KIAA1671 0.609666
SULF2 sulfatase 2 0.609666
UPP2 uridine phosphorylase 2 0.609666
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 0.607714
MTDH metadherin 0.60264
CD34 CD34 molecule 0.59874
MMP11 matrix metallopeptidase 11 0.593285
ADH6 alcohol dehydrogenase 6 (class V) 0.592506
LGTN ligatin 0.591337
TNC tenascin C 0.587444
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.580828
PLAUR plasminogen activator, urokinase receptor 0.580439
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.579272
CTSD cathepsin D 0.57655
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.566831
ZNF79 zinc finger protein 79 0.563335
MMP9 matrix metallopeptidase 9 0.549359
ARL5A ADP-ribosylation factor-like 5A 0.547032
SYTL5 synaptotagmin-like 5 0.546256
CHMP3 charged multivesicular body protein 3 0.545868
CD24 CD24 molecule 0.543542
COX7C cytochrome c oxidase subunit VIIc 0.542767
DYNLRB2 dynein, light chain, roadblock-type 2 0.541605
ZNF217 zinc finger protein 217 0.540442
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.538893
RUVBL1 RuvB-like AAA ATPase 1 0.526518
GATA3 GATA binding protein 3 0.52536
MUC6 mucin 6, oligomeric mucus/gel-forming 0.520346
CIRBP cold inducible RNA binding protein 0.514186
PAPL iron/zinc purple acid phosphatase-like protein 0.509192
MMP13 matrix metallopeptidase 13 0.504973
LRRC15 leucine rich repeat containing 15 0.502675
PTEN phosphatase and tensin homolog 0.502292
GTF3A general transcription factor IIIA 0.500761
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.499614
IVL involucrin 0.498467
S100Z S100 calcium binding protein Z 0.493503
KRT17 keratin 17, type I 0.490072
CALML3 calmodulin-like 3 0.489691
VEGFA vascular endothelial growth factor A 0.484364
BIRC5 baculoviral IAP repeat containing 5 0.483985
MLANA melan-A 0.481325
KRT10 keratin 10, type I 0.480945
CRLF3 cytokine receptor-like factor 3 0.480566
MET MET proto-oncogene, receptor tyrosine kinase 0.480186
ERBB3 erb-b2 receptor tyrosine kinase 3 0.479427
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.472604
PLAU plasminogen activator, urokinase 0.470711
KRT1 keratin 1, type II 0.469576
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.465038
MUC2 mucin 2, oligomeric mucus/gel-forming 0.462772
LARS leucyl-tRNA synthetase 0.462394
TRIM27 tripartite motif containing 27 0.461639
MRFAP1 Morf4 family associated protein 1 0.456732
NOTCH1 notch 1 0.453716
ANAPC4 anaphase promoting complex subunit 4 0.453339
BLID BH3-like motif containing, cell death inducer 0.450701
MAST2 microtubule associated serine/threonine kinase 2 0.445805
KDM2A lysine (K)-specific demethylase 2A 0.442795
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.440538
DLEC1 deleted in lung and esophageal cancer 1 0.435651
PELP1 proline, glutamate and leucine rich protein 1 0.433772
CLTCL1 clathrin, heavy chain-like 1 0.43227
KIAA0226L KIAA0226-like 0.431894
TYMP thymidine phosphorylase 0.431144
ANXA1 annexin A1 0.430768
VASH1 vasohibin 1 0.429266
PLXNA3 plexin A3 0.42739
RUNX3 runt-related transcription factor 3 0.427015
TGFB1 transforming growth factor, beta 1 0.425514
CDC6 cell division cycle 6 0.42364
IGFBP7 insulin-like growth factor binding protein 7 0.419892
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.418394
CHGA chromogranin A 0.415773
LGALS7B lectin, galactoside-binding, soluble, 7B 0.412405
HOXA1 homeobox A1 0.410909
DOK4 docking protein 4 0.410161
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.40904
MED10 mediator complex subunit 10 0.40904
CNN2 calponin 2 0.40008
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.397843
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.397098
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.39598
MT1G metallothionein 1G 0.394863
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.391513
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.390397
CDK4 cyclin-dependent kinase 4 0.388909
CD4 CD4 molecule 0.384451
MMP26 matrix metallopeptidase 26 0.383708
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.380739
KRAS Kirsten rat sarcoma viral oncogene homolog 0.378885
TRIM16 tripartite motif containing 16 0.378143
AADACL3 arylacetamide deacetylase-like 3 0.374068
MTMR12 myotubularin related protein 12 0.368149
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.364824
CRIP1 cysteine-rich protein 1 (intestinal) 0.364085
CADM4 cell adhesion molecule 4 0.362239
MIR21 microRNA 21 0.361502
ADGRE2 adhesion G protein-coupled receptor E2 0.357077
TMEM45A transmembrane protein 45A 0.356709
COX5B cytochrome c oxidase subunit Vb 0.356341
SPRR1A small proline-rich protein 1A 0.354868
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.354499
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.351187
APOD apolipoprotein D 0.349717
MMP1 matrix metallopeptidase 1 0.346409
NMT2 N-myristoyltransferase 2 0.346409
RPL15 ribosomal protein L15 0.342372
CINP cyclin-dependent kinase 2 interacting protein 0.342006
STS steroid sulfatase (microsomal), isozyme S 0.338707
PDYN prodynorphin 0.335046
MT1B metallothionein 1B 0.334681
EFTUD1 elongation factor Tu GTP binding domain containing 1 0.333583
HEATR6 HEAT repeat containing 6 0.330295
SFRP1 secreted frizzled-related protein 1 0.32774
CTNND1 catenin (cadherin-associated protein), delta 1 0.327375
NCAM1 neural cell adhesion molecule 1 0.32701
NEK2 NIMA-related kinase 2 0.32701
SMNDC1 survival motor neuron domain containing 1 0.32701
S100A6 S100 calcium binding protein A6 0.32373
HMGN1 high mobility group nucleosome binding domain 1 0.32373
CCND2 cyclin D2 0.322637
ERBB4 erb-b2 receptor tyrosine kinase 4 0.320817
DAP death-associated protein 0.320454
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.315729
GSTP1 glutathione S-transferase pi 1 0.311739
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.310652
SULF1 sulfatase 1 0.309204
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.309204
WDR77 WD repeat domain 77 0.307757
LGALS3 lectin, galactoside-binding, soluble, 3 0.30342
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.301254
DSG2 desmoglein 2 0.300173
TIMP3 TIMP metallopeptidase inhibitor 3 0.295132
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.29118
PGRMC2 progesterone receptor membrane component 2 0.290821
AKAP4 A kinase (PRKA) anchor protein 4 0.290462
NUSAP1 nucleolar and spindle associated protein 1 0.290462
DEPDC1 DEP domain containing 1 0.286519
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.28616
MMP7 matrix metallopeptidase 7 0.285444
CXCR4 chemokine (C-X-C motif) receptor 4 0.284728
BAX BCL2-associated X protein 0.283297
RBBP7 retinoblastoma binding protein 7 0.28294
MIA3 melanoma inhibitory activity family, member 3 0.281153
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.280439
IFNG interferon, gamma 0.280082
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.280082
FGFR1 fibroblast growth factor receptor 1 0.278654
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.276158
S100P S100 calcium binding protein P 0.274732
NMU neuromedin U 0.274021
ENO2 enolase 2 (gamma, neuronal) 0.272597
SDC1 syndecan 1 0.271886
MIR183 microRNA 183 0.271886
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.270464
RARB retinoic acid receptor, beta 0.270108
TTL tubulin tyrosine ligase 0.270108
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.270108
TOP2A topoisomerase (DNA) II alpha 170kDa 0.266913
S100A8 S100 calcium binding protein A8 0.266558
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.26514
CDX2 caudal type homeobox 2 0.264785
NRD1 nardilysin (N-arginine dibasic convertase) 0.264785
CSTA cystatin A (stefin A) 0.263368
HOXC4 homeobox C4 0.263014
ANOS1 anosmin 1 0.258064
MSH2 mutS homolog 2 0.256652
SFRP5 secreted frizzled-related protein 5 0.254536
NPTX1 neuronal pentraxin I 0.253831
RBPMS RNA binding protein with multiple splicing 0.253831
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.253479
CCNK cyclin K 0.253127
SPRR1B small proline-rich protein 1B 0.251015
CCNI cyclin I 0.246448
CCDC88A coiled-coil domain containing 88A 0.245747
KRT19 keratin 19, type I 0.245046
BCL9L B-cell CLL/lymphoma 9-like 0.243995
KIN Kin17 DNA and RNA binding protein 0.243645
LHX6 LIM homeobox 6 0.241895
DCD dermcidin 0.241895
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.241895
KRT15 keratin 15, type I 0.23945
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.239101
S100A2 S100 calcium binding protein A2 0.238403
NOTCH4 notch 4 0.235268
NEUROD2 neuronal differentiation 2 0.231795
TIMP1 TIMP metallopeptidase inhibitor 1 0.231795
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.231102
MIR145 microRNA 145 0.230755
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.230409
MICB MHC class I polypeptide-related sequence B 0.230409
F8 coagulation factor VIII, procoagulant component 0.226952
CCNE1 cyclin E1 0.225917
CDK11A cyclin-dependent kinase 11A 0.225573
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.22454
CAV1 caveolin 1, caveolae protein, 22kDa 0.221793
ECI1 enoyl-CoA delta isomerase 1 0.22145
ACVR1C activin A receptor, type IC 0.220424
RNASE7 ribonuclease, RNase A family, 7 0.220081
PRKCI protein kinase C, iota 0.219057
WT1 Wilms tumor 1 0.218034
MCM7 minichromosome maintenance complex component 7 0.218034
ASPH aspartate beta-hydroxylase 0.216332
IGF2 insulin-like growth factor 2 0.212608
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.212271
RB1 retinoblastoma 1 0.212271
KRT18 keratin 18, type I 0.211934
TP63 tumor protein p63 0.211261
RAB27B RAB27B, member RAS oncogene family 0.209918
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.208579
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.203933
COL11A1 collagen, type XI, alpha 1 0.198709
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.198709
ADAM9 ADAM metallopeptidase domain 9 0.198386
ASPN asporin 0.198064
PSRC1 proline/serine-rich coiled-coil 1 0.195183
CA2 carbonic anhydrase II 0.194865
ANXA8 annexin A8 0.194232
UPK1A uroplakin 1A 0.1936
AKTIP AKT interacting protein 0.1936
KIAA0196 KIAA0196 0.192971
NKD1 naked cuticle homolog 1 (Drosophila) 0.190786
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.190476
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.188632
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.187113
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.186811
RAB11A RAB11A, member RAS oncogene family 0.18621
SFRP4 secreted frizzled-related protein 4 0.18591
RHOB ras homolog family member B 0.185016
GLS2 glutaminase 2 (liver, mitochondrial) 0.183835
MRC2 mannose receptor, C type 2 0.182086
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.182086
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.181222
HOXA10 homeobox A10 0.180937
GLS glutaminase 0.180652
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.180084
CBX7 chromobox homolog 7 0.180084
DLL4 delta-like 4 (Drosophila) 0.175411
CA12 carbonic anhydrase XII 0.174354
VMP1 vacuole membrane protein 1 0.173571
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.173057
ANO7P1 anoctamin 7 pseudogene 1 0.172799
MIR98 microRNA 98 0.172544
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.172544
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.169091
TRIP10 thyroid hormone receptor interactor 10 0.165874
AKR1C3 aldo-keto reductase family 1, member C3 0.164359
KLHL21 kelch-like family member 21 0.163729
MIR31 microRNA 31 0.163317
STK25 serine/threonine kinase 25 0.162306
NKX2-1 NK2 homeobox 1 0.162306
JAG2 jagged 2 0.162306
TERT telomerase reverse transcriptase 0.160948
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.160761
FASLG Fas ligand (TNF superfamily, member 6) 0.160574
HPSE heparanase 0.159838
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.15948
VEGFC vascular endothelial growth factor C 0.159302
EPS8 epidermal growth factor receptor pathway substrate 8 0.158266
TIMP4 TIMP metallopeptidase inhibitor 4 0.157602
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.135956
UPK2 uroplakin 2 0.12943
CRLF1 cytokine receptor-like factor 1 0.125346
ITGA1 integrin, alpha 1 0.122493
EIF3A eukaryotic translation initiation factor 3, subunit A 0.122097
NRF1 nuclear respiratory factor 1 0.122019
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.119841
LINS lines homolog (Drosophila) 0.117388
POMP proteasome maturation protein 0.117206
SLURP1 secreted LY6/PLAUR domain containing 1 0.116606
ICAM2 intercellular adhesion molecule 2 0.116059
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.115812
IFI44 interferon-induced protein 44 0.11567
EYA4 EYA transcriptional coactivator and phosphatase 4 0.115541
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.1149
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.11474
TBX1 T-box 1 0.114618
TFAM transcription factor A, mitochondrial 0.114522
CLDN2 claudin 2 0.114439
MIR210 microRNA 210 0.114067
TMPRSS3 transmembrane protease, serine 3 0.11372
MIR185 microRNA 185 0.113635
PLXNA1 plexin A1 0.113422
CCAR2 cell cycle and apoptosis regulator 2 0.113294
RAB5A RAB5A, member RAS oncogene family 0.113251
CES1 carboxylesterase 1 0.113109
TMPRSS15 transmembrane protease, serine 15 0.112047
ICAM3 intercellular adhesion molecule 3 0.111762
VWF von Willebrand factor 0.110666
NBPF10 neuroblastoma breakpoint family, member 10 0.110589
SELPLG selectin P ligand 0.110496
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.110434
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.109742
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.109327
LXN latexin 0.107886
CD99 CD99 molecule 0.107768
FUS FUS RNA binding protein 0.107144
IFNA2 interferon, alpha 2 0.106074
MIR221 microRNA 221 0.105901
YBX1 Y box binding protein 1 0.105581
AMD1 adenosylmethionine decarboxylase 1 0.105065
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.104325
HNMT histamine N-methyltransferase 0.103538
PABPC1 poly(A) binding protein, cytoplasmic 1 0.103538
OXA1L oxidase (cytochrome c) assembly 1-like 0.103538
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.103519
CTSB cathepsin B 0.102921
TGM1 transglutaminase 1 0.10266
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.09961
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.09949
CCND3 cyclin D3 0.098869
GH1 growth hormone 1 0.098665
AMY1B amylase, alpha 1B (salivary) 0.097764
AMY1A amylase, alpha 1A (salivary) 0.097764
AMY1C amylase, alpha 1C (salivary) 0.097764
ANGPTL6 angiopoietin-like 6 0.097016
PRMT5 protein arginine methyltransferase 5 0.096305
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.095773
PLIN3 perilipin 3 0.095581
WWOX WW domain containing oxidoreductase 0.095325
MT1A metallothionein 1A 0.095303
FAM131C family with sequence similarity 131, member C 0.09526
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.095132
ARRB1 arrestin, beta 1 0.095111
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.095068
ANGPTL2 angiopoietin-like 2 0.094983
FOXA1 forkhead box A1 0.094898
NCOR2 nuclear receptor corepressor 2 0.094768
OPCML opioid binding protein/cell adhesion molecule-like 0.094506
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.094506
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.094332
ALK anaplastic lymphoma receptor tyrosine kinase 0.094267
OPA1 optic atrophy 1 (autosomal dominant) 0.094245
OLFM4 olfactomedin 4 0.094006
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.093984
GHR growth hormone receptor 0.093701
HOXA11 homeobox A11 0.093217
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.093039
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.092973
SIAH2 siah E3 ubiquitin protein ligase 2 0.092795
ANXA11 annexin A11 0.092707
CCL19 chemokine (C-C motif) ligand 19 0.092463
IGF2R insulin-like growth factor 2 receptor 0.092086
FOXM1 forkhead box M1 0.091995
POLB polymerase (DNA directed), beta 0.091995
NTM neurotrimin 0.091995
MUC4 mucin 4, cell surface associated 0.091973
PDCD5 programmed cell death 5 0.091973
BIN2 bridging integrator 2 0.09186
CLEC2A C-type lectin domain family 2, member A 0.091453
ECT2 epithelial cell transforming 2 0.091317
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.091205
HECA headcase homolog (Drosophila) 0.091159
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.091069
LUM lumican 0.091069
ALOX15B arachidonate 15-lipoxygenase, type B 0.090934
PRLR prolactin receptor 0.090844
LTBP1 latent transforming growth factor beta binding protein 1 0.090776
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.090731
AKR1C4 aldo-keto reductase family 1, member C4 0.09064
FOXO4 forkhead box O4 0.090617
EML4 echinoderm microtubule associated protein like 4 0.090571
VANGL1 VANGL planar cell polarity protein 1 0.090226
MIRLET7D microRNA let-7d 0.090042
HHIP hedgehog interacting protein 0.090019
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.089859
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.089859
NBPF8 neuroblastoma breakpoint family, member 8 0.089721
ANXA7 annexin A7 0.089192
NT5C2 5'-nucleotidase, cytosolic II 0.089192
MPG N-methylpurine-DNA glycosylase 0.088819
CCNG1 cyclin G1 0.088795
KIAA1524 KIAA1524 0.088235
GSTA3 glutathione S-transferase alpha 3 0.088165
CD207 CD207 molecule, langerin 0.088095
GSTA2 glutathione S-transferase alpha 2 0.088072
GSTA4 glutathione S-transferase alpha 4 0.088002
POLK polymerase (DNA directed) kappa 0.087979
PAX8 paired box 8 0.087721
HLA-C major histocompatibility complex, class I, C 0.087698
GSTA1 glutathione S-transferase alpha 1 0.08765
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.087484
KRT13 keratin 13, type I 0.087034
IRF9 interferon regulatory factor 9 0.086371
STAT5A signal transducer and activator of transcription 5A 0.08618
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.085867
SLC45A2 solute carrier family 45, member 2 0.085602
HLA-G major histocompatibility complex, class I, G 0.085578
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.08517
AKAP12 A kinase (PRKA) anchor protein 12 0.085026
CD40LG CD40 ligand 0.084882
GIF gastric intrinsic factor (vitamin B synthesis) 0.084713
SOX17 SRY (sex determining region Y)-box 17 0.084688
CD1B CD1b molecule 0.084274
LAMB3 laminin, beta 3 0.084103
CD200R1 CD200 receptor 1 0.084055
ODC1 ornithine decarboxylase 1 0.083933
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.083641
OSCAR osteoclast associated, immunoglobulin-like receptor 0.083446
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.083398
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.083325
KRT4 keratin 4, type II 0.083079
PF4 platelet factor 4 0.082215
STMN1 stathmin 1 0.082191
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.082043
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.081099
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.080974
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.080949
PAX2 paired box 2 0.0807
MAGEA4 melanoma antigen family A4 0.0805
PPARG peroxisome proliferator-activated receptor gamma 0.080152
PLA2G1B phospholipase A2, group IB (pancreas) 0.079899
CCL27 chemokine (C-C motif) ligand 27 0.079798
BARD1 BRCA1 associated RING domain 1 0.079697
DAXX death-domain associated protein 0.079571
CCNA1 cyclin A1 0.079118
TYR tyrosinase 0.079042
HHAT hedgehog acyltransferase 0.078866
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.078589
NCOR1 nuclear receptor corepressor 1 0.07836
MITF microphthalmia-associated transcription factor 0.07836
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.078284
EZR ezrin 0.078233
BAK1 BCL2-antagonist/killer 1 0.078105
RBMS1 RNA binding motif, single stranded interacting protein 1 0.077622
DKC1 dyskeratosis congenita 1, dyskerin 0.077317
WIF1 WNT inhibitory factor 1 0.076729
SFRP2 secreted frizzled-related protein 2 0.076704
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.076267
TFPI2 tissue factor pathway inhibitor 2 0.076242
EBAG9 estrogen receptor binding site associated, antigen, 9 0.076139
PHB prohibitin 0.075908
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.075652
CFLAR CASP8 and FADD-like apoptosis regulator 0.0756
ZNF135 zinc finger protein 135 0.075395
CST4 cystatin S 0.075163
CD22 CD22 molecule 0.074904
ALAS1 5'-aminolevulinate synthase 1 0.074852
FOS FBJ murine osteosarcoma viral oncogene homolog 0.074826
SETD2 SET domain containing 2 0.074645
FSCN3 fascin actin-bundling protein 3, testicular 0.074516
AXIN2 axin 2 0.074154
OCA2 oculocutaneous albinism II 0.074025
FLG filaggrin 0.073792
COL17A1 collagen, type XVII, alpha 1 0.073689
PBX1 pre-B-cell leukemia homeobox 1 0.073636
CD247 CD247 molecule 0.073506
MMP3 matrix metallopeptidase 3 0.073428
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.072959
SSTR1 somatostatin receptor 1 0.072855
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.072725
FSCN2 fascin actin-bundling protein 2, retinal 0.072673
CD200 CD200 molecule 0.072491
KLK7 kallikrein-related peptidase 7 0.072335
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.072231
SETD1A SET domain containing 1A 0.072127
HLA-B major histocompatibility complex, class I, B 0.07176
PENK proenkephalin 0.071289
TLR8 toll-like receptor 8 0.071132
CARD17 caspase recruitment domain family, member 17 0.07108
H2AFX H2A histone family, member X 0.071053
IFNGR1 interferon gamma receptor 1 0.071027
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.070897
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.070294
MCM2 minichromosome maintenance complex component 2 0.070189
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.069689
SFTPD surfactant protein D 0.06919
LMNB1 lamin B1 0.068874
TCHH trichohyalin 0.06832
CXCR3 chemokine (C-X-C motif) receptor 3 0.068003
ICAM1 intercellular adhesion molecule 1 0.067951
IHH indian hedgehog 0.067951
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.067924
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.067713
LOR loricrin 0.067687
WNT5A wingless-type MMTV integration site family, member 5A 0.067634
SMAD4 SMAD family member 4 0.067502
KLK3 kallikrein-related peptidase 3 0.067502
TCF3 transcription factor 3 0.067476
MIR223 microRNA 223 0.067133
IL10 interleukin 10 0.067054
YY1 YY1 transcription factor 0.067001
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.066895
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.066815
HLA-A major histocompatibility complex, class I, A 0.066524
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.06626
SMO smoothened, frizzled class receptor 0.06618
TWIST1 twist family bHLH transcription factor 1 0.066127
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.066022
NDRG1 N-myc downstream regulated 1 0.065995
FSCN1 fascin actin-bundling protein 1 0.065942
SMAD2 SMAD family member 2 0.065863
PEBP1 phosphatidylethanolamine binding protein 1 0.06581
DAPK1 death-associated protein kinase 1 0.065757
ATM ATM serine/threonine kinase 0.065625
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.065546
CDC25C cell division cycle 25C 0.065175
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.065095
LGALS7 lectin, galactoside-binding, soluble, 7 0.065042
MSLN mesothelin 0.064989
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.064963
IFNA1 interferon, alpha 1 0.064883
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.064857
IL2 interleukin 2 0.064698
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.064618
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.064592
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.064539
WISP2 WNT1 inducible signaling pathway protein 2 0.064539
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.064512
NRIP1 nuclear receptor interacting protein 1 0.064459