pre-eclampsia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy. (Human Disease Ontology, DOID_10591)
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Genes

650 genes co-occuring with the disease pre-eclampsia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PGF placental growth factor 2.67093
FLT1 fms-related tyrosine kinase 1 2.64435
LGALS13 lectin, galactoside-binding, soluble, 13 2.10091
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.98063
F5 coagulation factor V (proaccelerin, labile factor) 1.84272
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.78038
STOX1 storkhead box 1 1.73368
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 1.63411
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.60636
NOS3 nitric oxide synthase 3 (endothelial cell) 1.59072
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.57378
HLA-G major histocompatibility complex, class I, G 1.56533
LEP leptin 1.55646
GCM1 glial cells missing homolog 1 (Drosophila) 1.54539
F2 coagulation factor II (thrombin) 1.54098
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.5304
CSH2 chorionic somatomammotropin hormone 2 1.49526
VEGFA vascular endothelial growth factor A 1.46759
PAPPA2 pappalysin 2 1.46363
FN1 fibronectin 1 1.45353
EDN1 endothelin 1 1.45001
LNPEP leucyl/cystinyl aminopeptidase 1.43815
ADAM12 ADAM metallopeptidase domain 12 1.43639
ALB albumin 1.39652
REN renin 1.39389
NOTCH1 notch 1 1.3821
PROS1 protein S (alpha) 1.33501
INS insulin 1.31668
F2R coagulation factor II (thrombin) receptor 1.2992
PLG plasminogen 1.29658
F3 coagulation factor III (thromboplastin, tissue factor) 1.28523
GLS2 glutaminase 2 (liver, mitochondrial) 1.27257
TNF tumor necrosis factor 1.2656
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.24645
IGFBP1 insulin-like growth factor binding protein 1 1.24298
NPPA natriuretic peptide A 1.23733
VCAM1 vascular cell adhesion molecule 1 1.23473
PLAC1 placenta-specific 1 1.21348
CTBS chitobiase, di-N-acetyl- 1.19316
AFP alpha-fetoprotein 1.191
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.18712
CRP C-reactive protein, pentraxin-related 1.18195
THBD thrombomodulin 1.1755
SELE selectin E 1.16221
SOD2 superoxide dismutase 2, mitochondrial 1.15453
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.14645
HLA-C major histocompatibility complex, class I, C 1.14093
IL6 interleukin 6 1.13839
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.13078
ICAM1 intercellular adhesion molecule 1 1.12909
AGTR1 angiotensin II receptor, type 1 1.12825
GPX4 glutathione peroxidase 4 1.09755
ACE angiotensin I converting enzyme 1.09293
KNG1 kininogen 1 1.08915
GPX1 glutathione peroxidase 1 1.08873
VWF von Willebrand factor 1.08789
MGAM maltase-glucoamylase 1.08747
ERVW-1 endogenous retrovirus group W, member 1 1.07488
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.0669
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.06522
GPX5 glutathione peroxidase 5 1.0648
CRH corticotropin releasing hormone 1.06186
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.05009
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.04504
MIR210 microRNA 210 1.03451
ADM adrenomedullin 1.03282
FGR FGR proto-oncogene, Src family tyrosine kinase 1.02777
HMOX1 heme oxygenase 1 1.0168
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.00372
HP haptoglobin 0.986849
HPR haptoglobin-related protein 0.98011
MMP9 matrix metallopeptidase 9 0.976323
UNK unkempt family zinc finger 0.960378
HTRA4 HtrA serine peptidase 4 0.959123
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.948269
APOH apolipoprotein H (beta-2-glycoprotein I) 0.947852
CRHBP corticotropin releasing hormone binding protein 0.919261
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.915963
IGF1 insulin-like growth factor 1 (somatomedin C) 0.915551
TFPI2 tissue factor pathway inhibitor 2 0.91061
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.908965
CAT catalase 0.906086
ACVR2A activin A receptor, type IIA 0.895
LGALS1 lectin, galactoside-binding, soluble, 1 0.890078
KISS1 KiSS-1 metastasis-suppressor 0.880243
TGFB1 transforming growth factor, beta 1 0.879014
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.865093
IL1B interleukin 1, beta 0.849945
KDR kinase insert domain receptor 0.842982
IL10 interleukin 10 0.842982
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.842573
ANGPT2 angiopoietin 2 0.832329
MMP2 matrix metallopeptidase 2 0.822488
ANGPT1 angiopoietin 1 0.819616
TGFB3 transforming growth factor, beta 3 0.815514
RHD Rh blood group, D antigen 0.812642
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.81018
PROK1 prokineticin 1 0.808949
TTLL5 tubulin tyrosine ligase-like family member 5 0.802385
CDH5 cadherin 5, type 2 (vascular endothelium) 0.797872
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.796642
APEH acylaminoacyl-peptide hydrolase 0.788852
CORIN corin, serine peptidase 0.787213
DNAH8 dynein, axonemal, heavy chain 8 0.783526
ANXA5 annexin A5 0.781479
INHA inhibin, alpha 0.77575
TSPY3 testis specific protein, Y-linked 3 0.771661
TSPY10 testis specific protein, Y-linked 10 0.771661
LEPR leptin receptor 0.770435
C19ORF33 chromosome 19 open reading frame 33 0.767576
PSG9 pregnancy specific beta-1-glycoprotein 9 0.763902
HLA-A major histocompatibility complex, class I, A 0.763494
SPTB spectrin, beta, erythrocytic 0.756564
F8 coagulation factor VIII, procoagulant component 0.75412
ALPP alkaline phosphatase, placental 0.74883
ALPPL2 alkaline phosphatase, placental-like 2 0.74883
ALPL alkaline phosphatase, liver/bone/kidney 0.74761
HLA-E major histocompatibility complex, class I, E 0.738271
STOX2 storkhead box 2 0.734217
FST follistatin 0.728952
COMT catechol-O-methyltransferase 0.726929
SHBG sex hormone-binding globulin 0.726929
PRG4 proteoglycan 4 0.72612
SRY sex determining region Y 0.722482
IDO1 indoleamine 2,3-dioxygenase 1 0.72127
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.720865
TIMP1 TIMP metallopeptidase inhibitor 1 0.716425
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 0.712796
PLAT plasminogen activator, tissue 0.709572
HSPA4 heat shock 70kDa protein 4 0.706754
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.706754
AVP arginine vasopressin 0.705949
SIGLEC6 sialic acid binding Ig-like lectin 6 0.700722
NAMPT nicotinamide phosphoribosyltransferase 0.698313
ESAM endothelial cell adhesion molecule 0.693098
CST3 cystatin C 0.692697
TLR4 toll-like receptor 4 0.691896
NCAM1 neural cell adhesion molecule 1 0.691094
PCDHB7 protocadherin beta 7 0.678302
KRT18 keratin 18, type I 0.676706
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.674713
ANKRD37 ankyrin repeat domain 37 0.673917
ZSCAN1 zinc finger and SCAN domain containing 1 0.673518
ACTB actin, beta 0.668742
NOV nephroblastoma overexpressed 0.6608
CP ceruloplasmin (ferroxidase) 0.659215
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.65565
LCN2 lipocalin 2 0.654858
PAEP progestagen-associated endometrial protein 0.650903
FASLG Fas ligand (TNF superfamily, member 6) 0.650508
TIMP2 TIMP metallopeptidase inhibitor 2 0.649323
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.648138
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.640645
ACTG1 actin gamma 1 0.637102
RHCE Rh blood group, CcEe antigens 0.635921
NOSTRIN nitric oxide synthase trafficking 0.635528
IGFBP3 insulin-like growth factor binding protein 3 0.635135
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.626888
PDCD2L programmed cell death 2-like 0.623751
UTS2 urotensin 2 0.623359
ENG endoglin 0.622183
GSTA1 glutathione S-transferase alpha 1 0.618268
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.617486
CYR61 cysteine-rich, angiogenic inducer, 61 0.616312
CD63 CD63 molecule 0.612792
EDNRA endothelin receptor type A 0.610838
CPB2 carboxypeptidase B2 (plasma) 0.607323
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 0.607323
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.605762
SELL selectin L 0.604981
CLIC3 chloride intracellular channel 3 0.60225
INSL4 insulin-like 4 (placenta) 0.60225
PRDX5 peroxiredoxin 5 0.59913
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.598351
MZF1 myeloid zinc finger 1 0.586665
HBA2 hemoglobin, alpha 2 0.57655
FGD1 FYVE, RhoGEF and PH domain containing 1 0.575772
VSIG4 V-set and immunoglobulin domain containing 4 0.57305
CD4 CD4 molecule 0.569941
CD79A CD79a molecule, immunoglobulin-associated alpha 0.565666
HBA1 hemoglobin, alpha 1 0.562558
GSTA3 glutathione S-transferase alpha 3 0.562169
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.561781
GSTA2 glutathione S-transferase alpha 2 0.561004
GSTA4 glutathione S-transferase alpha 4 0.559839
ANG angiogenin, ribonuclease, RNase A family, 5 0.558674
POMC proopiomelanocortin 0.557897
SLAMF8 SLAM family member 8 0.555956
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.551686
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.550911
ACVR1C activin A receptor, type IC 0.544705
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.541992
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.541605
ERAP2 endoplasmic reticulum aminopeptidase 2 0.541605
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.540829
ERF Ets2 repressor factor 0.536957
UCN urocortin 0.535796
LYPD6 LY6/PLAUR domain containing 6 0.533861
PON1 paraoxonase 1 0.533088
HTRA1 HtrA serine peptidase 1 0.529994
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.528835
CXCL8 chemokine (C-X-C motif) ligand 8 0.525746
TMEM207 transmembrane protein 207 0.521502
C5AR1 complement component 5a receptor 1 0.520346
RETN resistin 0.51534
SLC41A3 solute carrier family 41, member 3 0.513802
FOXP3 forkhead box P3 0.51188
IGF2 insulin-like growth factor 2 0.511112
SH3PXD2A SH3 and PX domains 2A 0.508424
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.506123
GPX3 glutathione peroxidase 3 0.503441
ZNF699 zinc finger protein 699 0.501527
PTGIS prostaglandin I2 (prostacyclin) synthase 0.499231
RBP4 retinol binding protein 4, plasma 0.498849
TBXAS1 thromboxane A synthase 1 (platelet) 0.498849
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.497703
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 0.496557
TXN thioredoxin 0.495793
TF transferrin 0.495793
APOB apolipoprotein B 0.490454
AMBP alpha-1-microglobulin/bikunin precursor 0.486646
ENKUR enkurin, TRPC channel interacting protein 0.483604
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.481705
MMP1 matrix metallopeptidase 1 0.478289
PLAU plasminogen activator, urokinase 0.476393
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.472982
CALCRL calcitonin receptor-like 0.471846
APOC3 apolipoprotein C-III 0.471468
TACR3 tachykinin receptor 3 0.46466
CUEDC1 CUE domain containing 1 0.464283
ANGPTL6 angiopoietin-like 6 0.463527
HRG histidine-rich glycoprotein 0.462394
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.462016
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.460506
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.457864
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.457109
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.453716
SPIN4 spindlin family, member 4 0.453716
TLR2 toll-like receptor 2 0.448817
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.445805
DCTD dCMP deaminase 0.445052
LGALS14 lectin, galactoside-binding, soluble, 14 0.445052
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.444676
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.439786
EDF1 endothelial differentiation-related factor 1 0.438282
MCAM melanoma cell adhesion molecule 0.438282
ARL5B ADP-ribosylation factor-like 5B 0.429266
APOA1 apolipoprotein A-I 0.426265
PTH parathyroid hormone 0.422515
NELFCD negative elongation factor complex member C/D 0.420641
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.420266
EGFL7 EGF-like-domain, multiple 7 0.418394
CMA1 chymase 1, mast cell 0.41727
INHBA inhibin, beta A 0.413527
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.413153
VEGFC vascular endothelial growth factor C 0.413153
B2M beta-2-microglobulin 0.412779
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.411283
CHURC1 churchill domain containing 1 0.407545
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.407172
BOK BCL2-related ovarian killer 0.406051
INHBB inhibin, beta B 0.404931
FTL ferritin, light polypeptide 0.404184
FTH1 ferritin, heavy polypeptide 1 0.404184
PCDH12 protocadherin 12 0.401945
CBS cystathionine-beta-synthase 0.399707
COG2 component of oligomeric golgi complex 2 0.395608
ELANE elastase, neutrophil expressed 0.395608
CALCA calcitonin-related polypeptide alpha 0.392629
CNTNAP3 contactin associated protein-like 3 0.390025
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.388909
PF4 platelet factor 4 0.388166
FBXL20 F-box and leucine-rich repeat protein 20 0.387423
TEAD3 TEA domain family member 3 0.387051
HBEGF heparin-binding EGF-like growth factor 0.385193
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.384451
GDF2 growth differentiation factor 2 0.383708
CTRL chymotrypsin-like 0.381852
TIMP3 TIMP metallopeptidase inhibitor 3 0.381481
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.379997
BAX BCL2-associated X protein 0.375179
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.374809
PARD3 par-3 family cell polarity regulator 0.372958
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.372958
TBXA2R thromboxane A2 receptor 0.372587
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 0.372217
CFI complement factor I 0.370737
CADM1 cell adhesion molecule 1 0.370737
CPVL carboxypeptidase, vitellogenic-like 0.369258
CLEC4C C-type lectin domain family 4, member C 0.368888
SRPX2 sushi-repeat containing protein, X-linked 2 0.367779
AGER advanced glycosylation end product-specific receptor 0.36704
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.366671
IL18 interleukin 18 0.366671
ADORA2B adenosine A2b receptor 0.366671
IL4 interleukin 4 0.365193
ADAM30 ADAM metallopeptidase domain 30 0.364454
COL18A1 collagen, type XVIII, alpha 1 0.362978
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 0.362978
KCMF1 potassium channel modulatory factor 1 0.362239
IL1RN interleukin 1 receptor antagonist 0.358551
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.357814
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.355235
COL4A2 collagen, type IV, alpha 2 0.354499
TTR transthyretin 0.354131
CD209 CD209 molecule 0.352659
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.350452
IGLV1-51 immunoglobulin lambda variable 1-51 0.348981
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.348614
LPA lipoprotein, Lp(a) 0.346042
PLA2G1B phospholipase A2, group IB (pancreas) 0.345675
TLR3 toll-like receptor 3 0.345308
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.343473
UFL1 UFM1-specific ligase 1 0.342372
NDRG1 N-myc downstream regulated 1 0.342006
PRCP prolylcarboxypeptidase (angiotensinase C) 0.341639
SH2B2 SH2B adaptor protein 2 0.341639
INSL3 insulin-like 3 (Leydig cell) 0.341272
EHD4 EH-domain containing 4 0.340906
NONO non-POU domain containing, octamer-binding 0.339806
GATAD1 GATA zinc finger domain containing 1 0.338341
SLITRK4 SLIT and NTRK-like family, member 4 0.337242
MFSD2A major facilitator superfamily domain containing 2A 0.33651
KLF8 Kruppel-like factor 8 0.335046
INSL6 insulin-like 6 0.334315
GNLY granulysin 0.334315
ZFPL1 zinc finger protein-like 1 0.332852
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.327375
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.325916
TPO thyroid peroxidase 0.322273
ZBTB7B zinc finger and BTB domain containing 7B 0.321909
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.320454
IL31RA interleukin 31 receptor A 0.318999
CUTA cutA divalent cation tolerance homolog (E. coli) 0.317545
GSTP1 glutathione S-transferase pi 1 0.316456
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.316456
S100B S100 calcium binding protein B 0.316092
NOS2 nitric oxide synthase 2, inducible 0.315366
ADRB3 adrenoceptor beta 3 0.31464
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.31464
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.31464
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 0.314278
CFAP74 cilia and flagella associated protein 74 0.312827
LIG3 ligase III, DNA, ATP-dependent 0.312464
IGSF3 immunoglobulin superfamily, member 3 0.311739
SIAE sialic acid acetylesterase 0.31029
APOE apolipoprotein E 0.30848
EPHB4 EPH receptor B4 0.307395
NFE2L2 nuclear factor, erythroid 2-like 2 0.304864
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 0.303781
GSR glutathione reductase 0.302337
TFRC transferrin receptor 0.300173
ACOX2 acyl-CoA oxidase 2, branched chain 0.296211
BMP10 bone morphogenetic protein 10 0.295492
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 0.295492
LPL lipoprotein lipase 0.295492
FBL fibrillarin 0.295492
EFNB2 ephrin-B2 0.289744
KISS1R KISS1 receptor 0.286877
ARR3 arrestin 3, retinal (X-arrestin) 0.286519
CD34 CD34 molecule 0.285802
PIH2 pregnancy-induced hypertension syndrome-related protein 0.285086
TPRG1L tumor protein p63 regulated 1-like 0.284728
C6ORF25 chromosome 6 open reading frame 25 0.284728
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.28294
MPO myeloperoxidase 0.281868
KRT7 keratin 7, type II 0.280082
HADH hydroxyacyl-CoA dehydrogenase 0.280082
RXFP1 relaxin/insulin-like family peptide receptor 1 0.277584
DLX4 distal-less homeobox 4 0.277584
BTNL9 butyrophilin-like 9 0.277584
SDC1 syndecan 1 0.275445
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.275089
HSF1 heat shock transcription factor 1 0.274732
FEZF1 FEZ family zinc finger 1 0.274376
PRRC2A proline-rich coiled-coil 2A 0.274021
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.272953
NPPC natriuretic peptide C 0.271886
LDHA lactate dehydrogenase A 0.27153
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 0.268687
PER1 period circadian clock 1 0.268687
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.267267
CNN3 calponin 3, acidic 0.266913
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.266203
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.265849
NAAA N-acylethanolamine acid amidase 0.265849
CCL2 chemokine (C-C motif) ligand 2 0.265849
CXCL10 chemokine (C-X-C motif) ligand 10 0.264785
DBNL drebrin-like 0.264785
FEZF2 FEZ family zinc finger 2 0.264077
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.263014
CD40LG CD40 ligand 0.26266
ADA adenosine deaminase 0.260891
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.260538
PDIA3 protein disulfide isomerase family A, member 3 0.260184
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.25877
ANXA2 annexin A2 0.258417
CFB complement factor B 0.255946
PTPRE protein tyrosine phosphatase, receptor type, E 0.254888
GADD45A growth arrest and DNA-damage-inducible, alpha 0.254536
PSG8 pregnancy specific beta-1-glycoprotein 8 0.254536
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.25207
ECE1 endothelin converting enzyme 1 0.251718
ESR1 estrogen receptor 1 0.251366
INMT indolethylamine N-methyltransferase 0.249608
IL1A interleukin 1, alpha 0.248905
PROZ protein Z, vitamin K-dependent plasma glycoprotein 0.248554
ACE2 angiotensin I converting enzyme 2 0.24715
PZP pregnancy-zone protein 0.245396
PPARG peroxisome proliferator-activated receptor gamma 0.245046
FBLL1 fibrillarin-like 1 0.243295
PROKR1 prokineticin receptor 1 0.242245
CRHR1 corticotropin releasing hormone receptor 1 0.240847
AKT1S1 AKT1 substrate 1 (proline-rich) 0.240497
CDK11A cyclin-dependent kinase 11A 0.239799
OCLN occludin 0.238752
TTC34 tetratricopeptide repeat domain 34 0.238054
ASCL2 achaete-scute family bHLH transcription factor 2 0.237706
PFAS phosphoribosylformylglycinamidine synthase 0.23666
TXNRD3 thioredoxin reductase 3 0.232836
CYBA cytochrome b-245, alpha polypeptide 0.232142
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.231448
DCN decorin 0.231102
KIF17 kinesin family member 17 0.230755
TAC3 tachykinin 3 0.230063
NPR1 natriuretic peptide receptor 1 0.229024
GUCY2C guanylate cyclase 2C 0.228333
MAOA monoamine oxidase A 0.226262
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.225573
CNN2 calponin 2 0.222822
IL15 interleukin 15 0.222822
ESR2 estrogen receptor 2 (ER beta) 0.221793
TXNRD1 thioredoxin reductase 1 0.221108
GGCT gamma-glutamylcyclotransferase 0.219398
EHD3 EH-domain containing 3 0.218715
ERAP1 endoplasmic reticulum aminopeptidase 1 0.217693
C3 complement component 3 0.217693
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 0.217352
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.216672
CHMP5 charged multivesicular body protein 5 0.216332
GTF2H5 general transcription factor IIH, polypeptide 5 0.215992
PDGFC platelet derived growth factor C 0.215653
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.215314
SEBOX SEBOX homeobox 0.215314
ISCU iron-sulfur cluster assembly enzyme 0.214975
UCN3 urocortin 3 0.214297
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.213959
BHLHE40 basic helix-loop-helix family, member e40 0.213283
IL2 interleukin 2 0.211597
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.211261
EBAG9 estrogen receptor binding site associated, antigen, 9 0.210253
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.209918
HSPA1B heat shock 70kDa protein 1B 0.208579
EPAS1 endothelial PAS domain protein 1 0.206913
ITM2A integral membrane protein 2A 0.20658
GC group-specific component (vitamin D binding protein) 0.205916
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.205916
AQP9 aquaporin 9 0.205585
SYNPO synaptopodin 0.205254
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.205254
UCN2 urocortin 2 0.203604
CCDC27 coiled-coil domain containing 27 0.202618
CD46 CD46 molecule, complement regulatory protein 0.20229
ADIPOR2 adiponectin receptor 2 0.201962
SORBS1 sorbin and SH3 domain containing 1 0.201635
ACOT7 acyl-CoA thioesterase 7 0.200656
CFH complement factor H 0.200656
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.199033
BCHE butyrylcholinesterase 0.198064
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.197099
LARS leucyl-tRNA synthetase 0.197099
MIR26B microRNA 26b 0.19582
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.19582
C7 complement component 7 0.195501
CTSD cathepsin D 0.192031
URI1 URI1, prefoldin-like chaperone 0.191097
LUZP6 leucine zipper protein 6 0.189551
LHCGR luteinizing hormone/choriogonadotropin receptor 0.187719
VIMP VCP-interacting membrane selenoprotein 0.187415
HPD 4-hydroxyphenylpyruvate dioxygenase 0.186811
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.186811
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.185612
CD19 CD19 molecule 0.185313
AGTR2 angiotensin II receptor, type 2 0.185016
CFHR2 complement factor H-related 2 0.18472
MAEA macrophage erythroblast attacher 0.183835
HSPA1A heat shock 70kDa protein 1A 0.183541
LAP3 leucine aminopeptidase 3 0.183248
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.18151
FABP4 fatty acid binding protein 4, adipocyte 0.179239
LRRTM3 leucine rich repeat transmembrane neuronal 3 0.179239
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.178682
NFE2L3 nuclear factor, erythroid 2-like 3 0.178126
ADIPOR1 adiponectin receptor 1 0.177576
NOMO1 NODAL modulator 1 0.177576
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.176757
NADSYN1 NAD synthetase 1 0.176485
ETV7 ets variant 7 0.176215
ERP44 endoplasmic reticulum protein 44 0.174881
ATF3 activating transcription factor 3 0.174881
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.174881
CHIT1 chitinase 1 (chitotriosidase) 0.174354
PMCH pro-melanin-concentrating hormone 0.173832
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.173571
NPY neuropeptide Y 0.173314
PEX10 peroxisomal biogenesis factor 10 0.173057
SELENBP1 selenium binding protein 1 0.171785
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.171785
KAT8 K(lysine) acetyltransferase 8 0.171535
PDIA2 protein disulfide isomerase family A, member 2 0.171036
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.170789
C4BPA complement component 4 binding protein, alpha 0.170299
GPR183 G protein-coupled receptor 183 0.169812
ITGA1 integrin, alpha 1 0.16933
FBXW2 F-box and WD repeat domain containing 2 0.168617
MMP26 matrix metallopeptidase 26 0.168617
TNNI3 troponin I type 3 (cardiac) 0.168148
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.167452
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 0.166319
ACVR1B activin A receptor, type IB 0.165655
MET MET proto-oncogene, receptor tyrosine kinase 0.165001
LTF lactotransferrin 0.164571
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.163111
ERCC2 excision repair cross-complementation group 2 0.162505
SIGLEC9 sialic acid binding Ig-like lectin 9 0.162306
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.162306
GRB2 growth factor receptor-bound protein 2 0.162109
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.162109
DAXX death-domain associated protein 0.161716
CALR calreticulin 0.161716
FIGLA folliculogenesis specific basic helix-loop-helix 0.161331
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.161331
FGL2 fibrinogen-like 2 0.161139
IL2RA interleukin 2 receptor, alpha 0.160761
ANXA6 annexin A6 0.159302
DEFA4 defensin, alpha 4, corticostatin 0.158778
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.158434
UMOD uromodulin 0.158434
AKR1C3 aldo-keto reductase family 1, member C3 0.157929
GPANK1 G patch domain and ankyrin repeats 1 0.157602
LHB luteinizing hormone beta polypeptide 0.144033
CTHRC1 collagen triple helix repeat containing 1 0.143693
MMP8 matrix metallopeptidase 8 0.143669
LPAR2 lysophosphatidic acid receptor 2 0.143615
IL16 interleukin 16 0.143402
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.14331
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.143157
RERE arginine-glutamic acid dipeptide (RE) repeats 0.143032
AHSP alpha hemoglobin stabilizing protein 0.142967
WWTR1 WW domain containing transcription regulator 1 0.142889
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.142759
PARVA parvin, alpha 0.142323
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.142258
BBS1 Bardet-Biedl syndrome 1 0.141977
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.141832
RAET1E retinoic acid early transcript 1E 0.141737
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.141701
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.141603
AQP11 aquaporin 11 0.141176
BEX1 brain expressed, X-linked 1 0.140244
BEX2 brain expressed X-linked 2 0.140232
NEGR1 neuronal growth regulator 1 0.13964
ARSI arylsulfatase family, member I 0.139494
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.139449
AQP4 aquaporin 4 0.13939
KLHL21 kelch-like family member 21 0.139197
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.13887
WRAP73 WD repeat containing, antisense to TP73 0.138607
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.138012
EXOSC4 exosome component 4 0.137846
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.137546
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.13744
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.137232
DUSP9 dual specificity phosphatase 9 0.136788
LOC102724852 uncharacterized LOC102724852 0.13668
SAMD11 sterile alpha motif domain containing 11 0.136561
FERMT1 fermitin family member 1 0.136409
IL1RL1 interleukin 1 receptor-like 1 0.136357
SHD Src homology 2 domain containing transforming protein D 0.136138
AQP7 aquaporin 7 0.136128
AQP8 aquaporin 8 0.135956
POU3F4 POU class 3 homeobox 4 0.135758
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.135001
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.134928
LVRN laeverin 0.134767
PNMA1 paraneoplastic Ma antigen 1 0.133911
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.133884
CGB7 chorionic gonadotropin, beta polypeptide 7 0.133631
CGB5 chorionic gonadotropin, beta polypeptide 5 0.133574
FAM155B family with sequence similarity 155, member B 0.133487
SUOX sulfite oxidase 0.133223
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.133223
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.132608
ACADVL acyl-CoA dehydrogenase, very long chain 0.132608
CGB chorionic gonadotropin, beta polypeptide 0.132608
CGB8 chorionic gonadotropin, beta polypeptide 8 0.132577
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.132545
CPT2 carnitine palmitoyltransferase 2 0.132513
LAMP3 lysosomal-associated membrane protein 3 0.132432
POSTN periostin, osteoblast specific factor 0.132318
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.132154
RGS2 regulator of G-protein signaling 2 0.131936
PRDM2 PR domain containing 2, with ZNF domain 0.131936
SPATA21 spermatogenesis associated 21 0.131747
TALDO1 transaldolase 1 0.131643
ACSL1 acyl-CoA synthetase long-chain family member 1 0.131502
MMP17 matrix metallopeptidase 17 (membrane-inserted) 0.131359
COMMD1 copper metabolism (Murr1) domain containing 1 0.131324
LY75 lymphocyte antigen 75 0.131031
DLK1 delta-like 1 homolog (Drosophila) 0.130499
FAM132A family with sequence similarity 132, member A 0.129859
CLDN16 claudin 16 0.129715
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.12959
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.129483
LIPC lipase, hepatic 0.128962
NTN1 netrin 1 0.128556
IFNGR1 interferon gamma receptor 1 0.128533
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.128136
FAS Fas cell surface death receptor 0.128113
ASPH aspartate beta-hydroxylase 0.128042
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.127727
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.127504
BIN2 bridging integrator 2 0.127479
TREM1 triggering receptor expressed on myeloid cells 1 0.126711
VAMP8 vesicle-associated membrane protein 8 0.126444
PPT2 palmitoyl-protein thioesterase 2 0.12598
MMP28 matrix metallopeptidase 28 0.125814
SENP1 SUMO1/sentrin specific peptidase 1 0.1257
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.125329
PRSS8 protease, serine, 8 0.12527
CD8B CD8b molecule 0.125152
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.124585
CPN1 carboxypeptidase N, polypeptide 1 0.123902
AQP5 aquaporin 5 0.123839
CDA cytidine deaminase 0.123776
FLT4 fms-related tyrosine kinase 4 0.123582
HES5 hes family bHLH transcription factor 5 0.123517
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.123517
AQP1 aquaporin 1 (Colton blood group) 0.123091
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.122754
GPR182 G protein-coupled receptor 182 0.122552
RER1 retention in endoplasmic reticulum sorting receptor 1 0.122203
AQP3 aquaporin 3 (Gill blood group) 0.120753
POU2F3 POU class 2 homeobox 3 0.119945
JUNB jun B proto-oncogene 0.119905
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.119309
MANBA mannosidase, beta A, lysosomal 0.119063
CDKN2A cyclin-dependent kinase inhibitor 2A 0.118734
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.118187
EGLN2 egl-9 family hypoxia-inducible factor 2 0.118145