praziquantel-7228 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the praziquantel-7228 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
AK2 adenylate kinase 2
ALDOB aldolase B, fructose-bisphosphate
ASIC1 acid sensing (proton gated) ion channel 1
ATM ATM serine/threonine kinase
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAIAP3 BAI1-associated protein 3
BCL2 B-cell CLL/lymphoma 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CD300A CD300a molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CD8A CD8a molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CLCA2 chloride channel accessory 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COPZ2 coatomer protein complex, subunit zeta 2
CPD carboxypeptidase D
CSHL1 chorionic somatomammotropin hormone-like 1
CTBS chitobiase, di-N-acetyl-
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DPYS dihydropyrimidinase
DRD2 dopamine receptor D2
ELL elongation factor RNA polymerase II
FDPS farnesyl diphosphate synthase
FGB fibrinogen beta chain
FLT4 fms-related tyrosine kinase 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALR3 galanin receptor 3
GBP2 guanylate binding protein 2, interferon-inducible
GPR63 G protein-coupled receptor 63
GPR85 G protein-coupled receptor 85
GSAP gamma-secretase activating protein
HHEX hematopoietically expressed homeobox
HLA-DMB major histocompatibility complex, class II, DM beta
HR hair growth associated
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPG2 heparan sulfate proteoglycan 2
IGFBP5 insulin-like growth factor binding protein 5
IRF8 interferon regulatory factor 8
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KHSRP KH-type splicing regulatory protein
KIAA0319L KIAA0319-like
KIF1C kinesin family member 1C
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF12 Kruppel-like factor 12
KLHL22 kelch-like family member 22
LIN7A lin-7 homolog A (C. elegans)
MIIP migration and invasion inhibitory protein
MIR622 microRNA 622
MTA1 metastasis associated 1
MTSS1 metastasis suppressor 1
N4BP2L1 NEDD4 binding protein 2-like 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEU3 sialidase 3 (membrane sialidase)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL2 NIPA-like domain containing 2
PARD6B par-6 family cell polarity regulator beta
PARVA parvin, alpha
PCM1 pericentriolar material 1
PDE4C phosphodiesterase 4C, cAMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PML promyelocytic leukemia
PRDM2 PR domain containing 2, with ZNF domain
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RALGDS ral guanine nucleotide dissociation stimulator
RIF1 replication timing regulatory factor 1
RIN3 Ras and Rab interactor 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SETD1A SET domain containing 1A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNX13 sorting nexin 13
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRI sorcin
SSPN sarcospan
ST7 suppression of tumorigenicity 7
STK3 serine/threonine kinase 3
STOML1 stomatin (EPB72)-like 1
SVIL supervillin
SYT5 synaptotagmin V
TAT tyrosine aminotransferase
TBC1D17 TBC1 domain family, member 17
TMEM63A transmembrane protein 63A
TSPAN9 tetraspanin 9
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
VN1R1 vomeronasal 1 receptor 1
VPRBP Vpr (HIV-1) binding protein
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
ADGRE5 adhesion G protein-coupled receptor E5
AKAP12 A kinase (PRKA) anchor protein 12
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC6 armadillo repeat containing 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG2A autophagy related 2A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCAS1 breast carcinoma amplified sequence 1
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
C12ORF43 chromosome 12 open reading frame 43
C1ORF159 chromosome 1 open reading frame 159
C2ORF44 chromosome 2 open reading frame 44
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CBR4 carbonyl reductase 4
CCDC25 coiled-coil domain containing 25
CCNT1 cyclin T1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP131 centrosomal protein 131kDa
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DCAF17 DDB1 and CUL4 associated factor 17
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAAH fatty acid amide hydrolase
FAM169A family with sequence similarity 169, member A
FBXO2 F-box protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
GPR87 G protein-coupled receptor 87
GSTT1 glutathione S-transferase theta 1
HAUS6 HAUS augmin-like complex, subunit 6
HDAC3 histone deacetylase 3
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H2BO histone cluster 1, H2bo
IGFBP6 insulin-like growth factor binding protein 6
INF2 inverted formin, FH2 and WH2 domain containing
IRX4 iroquois homeobox 4
KLC2 kinesin light chain 2
LRRC61 leucine rich repeat containing 61
MED15 mediator complex subunit 15
MEIS1 Meis homeobox 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NBEAL2 neurobeachin-like 2
NLK nemo-like kinase
NRSN2 neurensin 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDZRN3 PDZ domain containing ring finger 3
PLD3 phospholipase D family, member 3
POLH polymerase (DNA directed), eta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
REST RE1-silencing transcription factor
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIBC2 RIB43A domain with coiled-coils 2
RPL13P5 ribosomal protein L13 pseudogene 5
SIRT6 sirtuin 6
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A9 solute carrier family 12, member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNX15 sorting nexin 15
SSFA2 sperm specific antigen 2
STX1A syntaxin 1A (brain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TDRD1 tudor domain containing 1
TEAD3 TEA domain family member 3
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TRABD TraB domain containing
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
YBX2 Y box binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZFP69B ZFP69 zinc finger protein B
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF141 zinc finger protein 141
ZNF492 zinc finger protein 492
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF669 zinc finger protein 669
ZNF672 zinc finger protein 672