practolol-4603 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


198 genes differentially expressed following the practolol-4603 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACVR1B activin A receptor, type IB
ADGRB1 adhesion G protein-coupled receptor B1
ADRB3 adrenoceptor beta 3
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
APOA2 apolipoprotein A-II
AQP4 aquaporin 4
ARHGAP15 Rho GTPase activating protein 15
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
C6ORF10 chromosome 6 open reading frame 10
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCL22 chemokine (C-C motif) ligand 22
CD101 CD101 molecule
CD58 CD58 molecule
CD6 CD6 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLEC1A C-type lectin domain family 1, member A
CLTC clathrin, heavy chain (Hc)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DICER1 dicer 1, ribonuclease type III
DRD2 dopamine receptor D2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDNRB endothelin receptor type B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FES FES proto-oncogene, tyrosine kinase
FGF18 fibroblast growth factor 18
FLT1 fms-related tyrosine kinase 1
FUS FUS RNA binding protein
GIPR gastric inhibitory polypeptide receptor
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPR143 G protein-coupled receptor 143
GUCY2C guanylate cyclase 2C
HEPH hephaestin
HEXIM1 hexamethylene bis-acetamide inducible 1
HFE hemochromatosis
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXD3 homeobox D3
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGKC immunoglobulin kappa constant
IHH indian hedgehog
KANSL3 KAT8 regulatory NSL complex subunit 3
KLHL25 kelch-like family member 25
KNG1 kininogen 1
KRT12 keratin 12, type I
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00652 long intergenic non-protein coding RNA 652
LOC390998 ribosomal protein L10 pseudogene
LRRN2 leucine rich repeat neuronal 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NF1 neurofibromin 1
NME8 NME/NM23 family member 8
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPFF neuropeptide FF-amide peptide precursor
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OSGIN2 oxidative stress induced growth inhibitor family member 2
OVOL1 ovo-like zinc finger 1
PADI4 peptidyl arginine deiminase, type IV
PAX3 paired box 3
PDLIM3 PDZ and LIM domain 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLN phospholamban
PRSS50 protease, serine, 50
PSG9 pregnancy specific beta-1-glycoprotein 9
PYHIN1 pyrin and HIN domain family, member 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RIMS3 regulating synaptic membrane exocytosis 3
RNF126P1 ring finger protein 126 pseudogene 1
RS1 retinoschisin 1
SAPCD1 suppressor APC domain containing 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SH2D1A SH2 domain containing 1A
SLAMF7 SLAM family member 7
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
STXBP5L syntaxin binding protein 5-like
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TACR1 tachykinin receptor 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOX3 TOX high mobility group box family member 3
TP53I11 tumor protein p53 inducible protein 11
TPM1 tropomyosin 1 (alpha)
UST uronyl-2-sulfotransferase
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP5 vesicle-associated membrane protein 5
VIPR2 vasoactive intestinal peptide receptor 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WIPF1 WAS/WASL interacting protein family, member 1
WNT2B wingless-type MMTV integration site family, member 2B
ZHX3 zinc fingers and homeoboxes 3
ZNF3 zinc finger protein 3
ZNF549 zinc finger protein 549
ZNF814 zinc finger protein 814

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABHD17B abhydrolase domain containing 17B
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKHD1 ankyrin repeat and KH domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
BAHCC1 BAH domain and coiled-coil containing 1
BCAS3 breast carcinoma amplified sequence 3
C9ORF40 chromosome 9 open reading frame 40
CDADC1 cytidine and dCMP deaminase domain containing 1
CFAP44 cilia and flagella associated protein 44
CLDN4 claudin 4
CTSO cathepsin O
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
EGF epidermal growth factor
EXOC2 exocyst complex component 2
FBXO3 F-box protein 3
FGF13 fibroblast growth factor 13
FOXC1 forkhead box C1
FZD8 frizzled class receptor 8
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAREM GRB2 associated, regulator of MAPK1
GCHFR GTP cyclohydrolase I feedback regulator
GPHN gephyrin
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HOXA4 homeobox A4
IGSF3 immunoglobulin superfamily, member 3
KATNBL1 katanin p80 subunit B-like 1
KIAA1456 KIAA1456
KIAA1462 KIAA1462
KIF16B kinesin family member 16B
KLHL3 kelch-like family member 3
KRT34 keratin 34, type I
LRRC42 leucine rich repeat containing 42
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MB myoglobin
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTERF4 mitochondrial transcription termination factor 4
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NDP Norrie disease (pseudoglioma)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARP3 poly (ADP-ribose) polymerase family, member 3
PCOLCE procollagen C-endopeptidase enhancer
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRR15L proline rich 15-like
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RIN1 Ras and Rab interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF25 ring finger protein 25
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GL2 SH3-domain GRB2-like 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLIT2 slit homolog 2 (Drosophila)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPIDR scaffolding protein involved in DNA repair
STAC SH3 and cysteine rich domain
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SYTL2 synaptotagmin-like 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM120B transmembrane protein 120B
TMEM242 transmembrane protein 242
TRIP10 thyroid hormone receptor interactor 10
TSPAN1 tetraspanin 1
TTBK2 tau tubulin kinase 2
UBAC1 UBA domain containing 1
ZFHX3 zinc finger homeobox 3
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF767P zinc finger family member 767, pseudogene
ZNF770 zinc finger protein 770