practolol-3204 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the practolol-3204 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADRA1B adrenoceptor alpha 1B
AFAP1 actin filament associated protein 1
ALOXE3 arachidonate lipoxygenase 3
ANKRD53 ankyrin repeat domain 53
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB4 ankyrin repeat and SOCS box containing 4
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BST1 bone marrow stromal cell antigen 1
C2ORF27A chromosome 2 open reading frame 27A
C5AR1 complement component 5a receptor 1
CA4 carbonic anhydrase IV
CASQ2 calsequestrin 2 (cardiac muscle)
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD52 CD52 molecule
CD96 CD96 molecule
CDC42 cell division cycle 42
COL10A1 collagen, type X, alpha 1
COL6A1 collagen, type VI, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTIF CBP80/20-dependent translation initiation factor
CYB5A cytochrome b5 type A (microsomal)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DRD2 dopamine receptor D2
DVL3 dishevelled segment polarity protein 3
EPN1 epsin 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAS7 growth arrest-specific 7
GLIPR1 GLI pathogenesis-related 1
GLRX3 glutaredoxin 3
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HSPB3 heat shock 27kDa protein 3
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBSP integrin-binding sialoprotein
IDS iduronate 2-sulfatase
IFT27 intraflagellar transport 27
IGL immunoglobulin lambda locus
INADL InaD-like (Drosophila)
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LSP1 lymphocyte-specific protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTMR7 myotubularin related protein 7
NDN necdin, melanoma antigen (MAGE) family member
NEUROD1 neuronal differentiation 1
NME5 NME/NM23 family member 5
NPR3 natriuretic peptide receptor 3
OBSL1 obscurin-like 1
OSMR oncostatin M receptor
PBOV1 prostate and breast cancer overexpressed 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PPARA peroxisome proliferator-activated receptor alpha
PRM1 protamine 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTHLH parathyroid hormone-like hormone
REEP2 receptor accessory protein 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEC24D SEC24 family member D
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLMO1 slowmo homolog 1 (Drosophila)
SLN sarcolipin
SPAG6 sperm associated antigen 6
SPON1 spondin 1, extracellular matrix protein
SPRR1A small proline-rich protein 1A
TACR1 tachykinin receptor 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM53 transmembrane protein 53
TMOD1 tropomodulin 1
TNNC2 troponin C type 2 (fast)
TRAK1 trafficking protein, kinesin binding 1
TRIM49 tripartite motif containing 49
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSC22D2 TSC22 domain family, member 2
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
VASH1 vasohibin 1
WIZ widely interspaced zinc finger motifs
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF589 zinc finger protein 589
ZNF750 zinc finger protein 750
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ART1 ADP-ribosyltransferase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL9 B-cell CLL/lymphoma 9
C19ORF73 chromosome 19 open reading frame 73
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CES1 carboxylesterase 1
CGA glycoprotein hormones, alpha polypeptide
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DEAF1 DEAF1 transcription factor
DUSP13 dual specificity phosphatase 13
EGFL7 EGF-like-domain, multiple 7
FAM131A family with sequence similarity 131, member A
FILIP1L filamin A interacting protein 1-like
FKBP2 FK506 binding protein 2, 13kDa
FRS2 fibroblast growth factor receptor substrate 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIRA histone cell cycle regulator
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HIST2H2AA3 histone cluster 2, H2aa3
HOXC5 homeobox C5
ITGA10 integrin, alpha 10
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
LIN7B lin-7 homolog B (C. elegans)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MOCS3 molybdenum cofactor synthesis 3
MRPS18C mitochondrial ribosomal protein S18C
MT1H metallothionein 1H
MTA2 metastasis associated 1 family, member 2
NDE1 nudE neurodevelopment protein 1
NFE2L3 nuclear factor, erythroid 2-like 3
NLGN1 neuroligin 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDHGB5 protocadherin gamma subfamily B, 5
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PPT2 palmitoyl-protein thioesterase 2
PRR4 proline rich 4 (lacrimal)
RAB32 RAB32, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF121 ring finger protein 121
SAYSD1 SAYSVFN motif domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRY2 sprouty homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
SYNC syncoilin, intermediate filament protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TESC tescalcin
TH tyrosine hydroxylase
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMC7 transmembrane channel-like 7
TMEM110 transmembrane protein 110
TMEM180 transmembrane protein 180
TRIM25 tripartite motif containing 25
TTC26 tetratricopeptide repeat domain 26
TUBA3C tubulin, alpha 3c
VGF VGF nerve growth factor inducible
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H12A zinc finger CCCH-type containing 12A
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF586 zinc finger protein 586
ZSCAN26 zinc finger and SCAN domain containing 26