positive transcription elongation factor complex b Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains cyclin T and a cyclin-dependent protein kinase catalytic subunit. (Gene Ontology, GO_0008024)
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145 proteins co-occuring with the positive transcription elongation factor complex b cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDK9 cyclin-dependent kinase 9 3.58408
CCNT1 cyclin T1 3.35582
HEXIM1 hexamethylene bis-acetamide inducible 1 2.81522
BRD4 bromodomain containing 4 2.10129
TAT tyrosine aminotransferase 1.94181
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.79707
AFF4 AF4/FMR2 family, member 4 1.76561
CCNT2 cyclin T2 1.76303
LARP7 La ribonucleoprotein domain family, member 7 1.73561
HEXIM2 hexamethylene bis-acetamide inducible 2 1.68665
CCNK cyclin K 1.67629
JAG2 jagged 2 1.64852
CDK7 cyclin-dependent kinase 7 1.51525
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 1.36857
MEPCE methylphosphate capping enzyme 1.36362
ELL2 elongation factor, RNA polymerase II, 2 1.30981
ELL elongation factor RNA polymerase II 1.28196
AFF1 AF4/FMR2 family, member 1 1.24341
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.22724
AFF3 AF4/FMR2 family, member 3 0.938795
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.927483
ZNF512 zinc finger protein 512 0.918111
CDK8 cyclin-dependent kinase 8 0.871346
BRD2 bromodomain containing 2 0.811652
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.807524
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.75317
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.752263
DOT1L DOT1-like histone H3K79 methyltransferase 0.750452
CDK12 cyclin-dependent kinase 12 0.738713
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.736014
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.721242
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.682027
CIITA class II, major histocompatibility complex, transactivator 0.668992
H3F3A H3 histone, family 3A 0.666394
H3F3B H3 histone, family 3B (H3.3B) 0.666394
KAT2B K(lysine) acetyltransferase 2B 0.6638
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.662072
HMGA1 high mobility group AT-hook 1 0.643572
PPP1R10P1 protein phosphatase 1, regulatory subunit 10 pseudogene 1 0.630745
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.610778
MED26 mediator complex subunit 26 0.60655
AFF2 AF4/FMR2 family, member 2 0.593492
CD4 CD4 molecule 0.588456
ELL3 elongation factor RNA polymerase II-like 3 0.578416
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.552251
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.492966
BRDT bromodomain, testis-specific 0.492157
HSPA4 heat shock 70kDa protein 4 0.485289
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.472412
SNW1 SNW domain containing 1 0.465198
TOX3 TOX high mobility group box family member 3 0.447259
IWS1 IWS1 homolog (S. cerevisiae) 0.439333
HIST2H2BF histone cluster 2, H2bf 0.431435
HIST3H2BB histone cluster 3, H2bb 0.431435
HIST1H2BH histone cluster 1, H2bh 0.431435
HIST1H2BD histone cluster 1, H2bd 0.431041
HIST1H2BC histone cluster 1, H2bc 0.429859
HIST1H2BF histone cluster 1, H2bf 0.429859
HIST1H2BA histone cluster 1, H2ba 0.428678
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.420428
MDFI MyoD family inhibitor 0.419644
HIST2H4A histone cluster 2, H4a 0.416511
HIST1H4K histone cluster 1, H4k 0.416511
HIST2H4B histone cluster 2, H4b 0.416511
HIST1H4J histone cluster 1, H4j 0.416511
HIST1H4B histone cluster 1, H4b 0.416511
HIST1H4D histone cluster 1, H4d 0.416511
HIST1H4A histone cluster 1, H4a 0.416511
HIST1H4F histone cluster 1, H4f 0.416511
HIST1H4H histone cluster 1, H4h 0.416511
HIST1H4I histone cluster 1, H4i 0.416511
HIST1H4E histone cluster 1, H4e 0.416511
HIST1H4C histone cluster 1, H4c 0.416511
HIST1H4L histone cluster 1, H4l 0.41612
HIST4H4 histone cluster 4, H4 0.41612
AIRE autoimmune regulator 0.390455
HIC2 hypermethylated in cancer 2 0.390068
CDC37 cell division cycle 37 0.390068
BRD3 bromodomain containing 3 0.389682
PRDM14 PR domain containing 14 0.383509
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.380429
SETD2 SET domain containing 2 0.378507
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.37505
GRN granulin 0.372749
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.365095
DEFA1B defensin, alpha 1B 0.349105
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.341907
TEF thyrotrophic embryonic factor 0.338506
DEFA1 defensin, alpha 1 0.334356
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.333225
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.331342
SP3 Sp3 transcription factor 0.330966
RUNX1 runt-related transcription factor 1 0.322325
LMO2 LIM domain only 2 (rhombotin-like 1) 0.32195
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.318953
CDK4 cyclin-dependent kinase 4 0.311851
NELFA negative elongation factor complex member A 0.311851
GTF2B general transcription factor IIB 0.30626
SKI SKI proto-oncogene 0.305143
CDK2 cyclin-dependent kinase 2 0.298826
FBXO11 F-box protein 11 0.292527
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.289938
CDK13 cyclin-dependent kinase 13 0.285876
RBM23 RNA binding motif protein 23 0.281821
ILF3 interleukin enhancer binding factor 3, 90kDa 0.281085
EEF1G eukaryotic translation elongation factor 1 gamma 0.279612
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.278509
JMJD6 jumonji domain containing 6 0.275936
TBP TATA box binding protein 0.264215
SMYD3 SET and MYND domain containing 3 0.258745
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.256197
MC5R melanocortin 5 receptor 0.252202
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.238837
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.238478
MYOD1 myogenic differentiation 1 0.232029
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.228819
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.228464
WDR82 WD repeat domain 82 0.225622
CBX8 chromobox homolog 8 0.224204
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.217511
HIPK3 homeodomain interacting protein kinase 3 0.217511
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.211587
HSF1 heat shock transcription factor 1 0.209513
FOS FBJ murine osteosarcoma viral oncogene homolog 0.209169
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.202009
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 0.198658
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.196669
BCOR BCL6 corepressor 0.195025
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.194045
TP53 tumor protein p53 0.193719
KMT2A lysine (K)-specific methyltransferase 2A 0.186708
MED23 mediator complex subunit 23 0.185777
NUTM1 NUT midline carcinoma, family member 1 0.182723
KIAA0101 KIAA0101 0.178877
SETD1A SET domain containing 1A 0.158882
WRNIP1 Werner helicase interacting protein 1 0.157039
FOXC2 forkhead box C2 0.156513
ELP3 elongator acetyltransferase complex subunit 3 0.145704
NUP133 nucleoporin 133kDa 0.142805
CCNC cyclin C 0.142592
PYCR1 pyrroline-5-carboxylate reductase 1 0.140548
SLK STE20-like kinase 0.139552
MATK megakaryocyte-associated tyrosine kinase 0.136945
POLI polymerase (DNA directed) iota 0.135906
BRCA1 breast cancer 1, early onset 0.129365