positive regulation of t cell activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of T cell activation. (Gene Ontology, GO_0050870)
External Link http://amigo.geneontology.org/amigo/term/GO:0050870
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Genes

176 genes participating in the positive regulation of t cell activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADA adenosine deaminase
ADAM8 ADAM metallopeptidase domain 8
ADK adenosine kinase
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
BAD BCL2-associated agonist of cell death
BCL10 B-cell CLL/lymphoma 10
BLM Bloom syndrome, RecQ helicase-like
BTLA B and T lymphocyte associated
CARD11 caspase recruitment domain family, member 11
CAV1 caveolin 1, caveolae protein, 22kDa
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CD1D CD1d molecule
CD24 CD24 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD5 CD5 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CORO1A coronin, actin binding protein, 1A
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DHPS deoxyhypusine synthase
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPP4 dipeptidyl-peptidase 4
EBI3 Epstein-Barr virus induced 3
EFNB1 ephrin-B1
EGR3 early growth response 3
FADD Fas (TNFRSF6)-associated via death domain
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HES1 hes family bHLH transcription factor 1
HHLA2 HERV-H LTR-associating 2
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IHH indian hedgehog
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RL2 interleukin 1 receptor-like 2
IL2 interleukin 2
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL36B interleukin 36, beta
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
JAK3 Janus kinase 3
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYB v-myb avian myeloblastosis viral oncogene homolog
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NKAP NFKB activating protein
NOD2 nucleotide-binding oligomerization domain containing 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PNP purine nucleoside phosphorylase
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARA retinoic acid receptor, alpha
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK2 receptor-interacting serine-threonine kinase 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
SART1 squamous cell carcinoma antigen recognized by T cells
SASH3 SAM and SH3 domain containing 3
SHH sonic hedgehog
SIRPG signal-regulatory protein gamma
SOCS5 suppressor of cytokine signaling 5
SPTA1 spectrin, alpha, erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TESPA1 thymocyte expressed, positive selection associated 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4